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27-07-2016 | Original Paper | Uitgave 10/2016

Dual Cognitive and Biological Correlates of Anxiety in Autism Spectrum Disorders

Tijdschrift:: Journal of Autism and Developmental Disorders > Uitgave 10/2016

Auteurs:: Matthew J. Hollocks, Andrew Pickles, Patricia Howlin, Emily Simonoff

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Abstract

Young people with autism spectrum disorder (ASD) have a high prevalence (~40 %) of anxiety disorders compared to their non-ASD peers. It is unclear whether cognitive and biological processes associated with anxiety in ASD are analogous to anxiety in typically developing (TD) populations. In this study 55 boys with ASD (34 with a co-occurring anxiety disorder, 21 without) and 28 male controls, aged 10–16 years and with a full-scale IQ ≥ 70, completed a series of clinical, cognitive (attention bias/interpretation bias) and biological measures (salivary cortisol/HR response to social stress) associated with anxiety in TD populations. Structural equation modelling was used to reveal that that both attentional biases and physiological responsiveness were significant, but unrelated, predictors of anxiety in ASD.

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Titel: Dual Cognitive and Biological Correlates of Anxiety in Autism Spectrum Disorders
Auteurs:: Matthew J. Hollocks
Andrew Pickles
Patricia Howlin
Emily Simonoff
Publicatiedatum: 27-07-2016
DOI: https://doi.org/10.1007/s10803-016-2878-2
Uitgeverij: Springer US
Tijdschrift: Journal of Autism and Developmental Disorders
Uitgave 10/2016
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432

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