Tip

Swipe om te navigeren naar een ander artikel

01-02-2007 | Original Paper | Uitgave 2/2007

MMR-Vaccine and Regression in Autism Spectrum Disorders: Negative Results Presented from Japan

Tijdschrift:: Journal of Autism and Developmental Disorders > Uitgave 2/2007

Auteurs:: Tokio Uchiyama, Michiko Kurosawa, Yutaka Inaba

» Toegang tot de volledige tekst krijgen

Abstract

It has been suggested that the measles, mumps, and rubella vaccine (MMR) is a cause of regressive autism. As MMR was used in Japan only between 1989 and 1993, this time period affords a natural experiment to examine this hypothesis. Data on 904 patients with autism spectrum disorders (ASD) were analyzed. During the period of MMR usage no significant difference was found in the incidence of regression between MMR-vaccinated children and non-vaccinated children. Among the proportion and incidence of regression across the three MMR-program-related periods (before, during and after MMR usage), no significant difference was found between those who had received MMR and those who had not. Moreover, the incidence of regression did not change significantly across the three periods.

Log in om toegang te krijgen

Hier inloggen

Met onderstaand(e) abonnement(en) heeft u direct toegang:

BSL Psychologie Totaal

Met BSL Psychologie Totaal blijft u als professional steeds op de hoogte van de nieuwste ontwikkelingen binnen uw vak. Met het online abonnement heeft u toegang tot een groot aantal boeken, protocollen, vaktijdschriften en e-learnings op het gebied van psychologie en psychiatrie. Zo kunt u op uw gemak en wanneer het u het beste uitkomt verdiepen in uw vakgebied.

Meer informatie

American Psychiatric Association (1994). Diagnostic and statistical manual of mental disorders. (4th ed.). Washington, D. C.: Author.

Azuma, H., Ueno, K., Fujita, K., Maekawa, H., Ishikuma, T., & Sano, H. (1998). Nihonban WISC-III Tinou-Kensaho. Nihonbunkakagakusha (Japanese version of WISC-III: Translated and standardized to Japanese children by the ad hoc committee).

Fombonne, E., & Chakrabarti, S. (2001). No evidence for a new variant of measles–mumps–rubella-induced autism. Pediatrics, 108, E58. PubMedCrossRef

Hoshino, Y., Kaneko, M., Yashima, Y., Kumashiro, H., Volkmar, F. R., & Cohen, D. J. (1987). Clinical features of autistic children with setback course in their infancy. Japanese Journal of Psychiatry and Neurology, 41, 237–245. PubMed

Kaye, J. A., del Mar Melero-Montes, M., & Jick, H. (2001). Mumps, measles, and rubella vaccine and the incidence of autism recorded by general practitioners: a time trend analysis. BMJ, 322, 460–463. PubMedCrossRef

Kurita, H. (1996). Specificity and developmental consequences of speech loss in children with pervasive developmental disorders. Psychiatry and Clinical Neurosciences, 50, 363–387.

Madsen, K. M., Hviid, A., Vestergaard, M., Schendel, D., Wohlfahrt, J., Thorsen, P., Olsen, J., & Melbye, M. (2002) A population-based study of measles, mumps, and rubella vaccination and autism. New England Journal of Medicine, 347, 1477–1482. PubMedCrossRef

Makela, A., Nuorti, J. P., & Peltola, H. (2002). Neurologic disorders after measles–mumps–rubella vaccination. Pediatrics, 110, 957–963. PubMedCrossRef

Shopler, E., Reichler, R., Bashford, A., Lansing, M. D., & Marcus, L. M. (1990). Psycoeducational profile-revised (PEP-R) . Austin, TC-Pro-Ed. (Translated to Japanese by Ibaraki T, 1995, Kawashima-syoten, Tokyo.).

Sugiura, A., & Yamada, A. (1991). Aseptic meningitis as a complication of mumps vaccination. The Pediatric Infectious Disease Journal, 10, 209–213. PubMedCrossRef

Takahashi, H., Arai, S., Tanaka-Taya, K., & Okabe, N. (2001). Autism and infection/immunization episodes in Japan. Japanese Journal of Infectious Diseases, 54, 78–79. PubMed

Takahashi, H., Suzumura, S., Shirakisawa, F., Wada, N., Tanaka-Taya, K., Arai, S., Okabe, N., Ichikawa, H., & Sato, T. (2003). An epidemiological study on Japanese autism concerning routine childhood immunization history. Japanese Journal of Infectious Diseases, 56, 114–117. PubMed

Tanaka, K-K. (1987). Tanaka-Binet tinou kensaho. Tokyo: Taken shuppan publisher (in Japanese).

Taylor, B., Miller, E., Farrington, C. P., Petropoulos, M. C., Favot-Mayaud, I., Jun, L., & Waight, P. A. (1999). Autism and measles, mumps, and rubella vaccine: no epidemiological evidence for a causal association. Lancet, 353, 2026–2029. PubMedCrossRef

Taylor, B., Miller, E., Lingram, L., Andrews, N., Simmons, A., & Stowe, J. (2002). Measles, mumps, and rubella vaccination and bowel problems or developmental regression in children with autism: population study. BMJ, 324, 393–396. PubMedCrossRef

Tuchman, R. F., & Rapin, I. (1997). Regression in pervasive developmental disorders: seizures and epileptiform electroencephalogram correlates. Pediatrics, 99, 560–566. PubMedCrossRef

Wakefield, A. J., Murch, S. H., Anthony, A., Linnell, J., Casson, D. M., Malik, M., Berelowitz, M., Dhillon, A. P., Thomson, M. A., Harvey, P., Valentine, A., Davies, S. E., & Walker-Smith, J. A. (1998). Ileal-lymphoid-nodular hyperplasia, non-specific colitis, and pervasive developmental disorder in children. Lancet, 351, 637–641. PubMedCrossRef

Titel: MMR-Vaccine and Regression in Autism Spectrum Disorders: Negative Results Presented from Japan
Auteurs:: Tokio Uchiyama
Michiko Kurosawa
Yutaka Inaba
Publicatiedatum: 01-02-2007
DOI: https://doi.org/10.1007/s10803-006-0157-3
Uitgeverij: Kluwer Academic Publishers-Plenum Publishers
Tijdschrift: Journal of Autism and Developmental Disorders
Uitgave 2/2007
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432

Bohn Stafleu van Loghum

Deel dit onderdeel of sectie (kopieer de link)

Tip

Swipe om te navigeren naar een ander artikel

Abstract

Log in om toegang te krijgen

Met onderstaand(e) abonnement(en) heeft u direct toegang:

BSL Psychologie Totaal

Andere artikelen Uitgave 2/2007

Brief Report: Application of the TEACCH Program on Chinese Pre-School Children with Autism––Does Culture Make a Difference?

Division TEACCH Offers Classroom Training Program for Summer 2007 in Chapel Hill

Risperidone Improves Behavioral Symptoms in Children with Autism in a Randomized, Double-Blind, Placebo-Controlled Trial

Priming the Meaning of Homographs in Typically Developing Children and Children with Autism

Cognitive and Verbal Abilities of 24- to 36-month-old Siblings of Children with Autism

Autobiographical Memory and Social Problem-solving in Asperger Syndrome