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Gepubliceerd in: Journal of Autism and Developmental Disorders 7/2013

01-07-2013 | Original Paper

The Relationship Between Grey-Matter and ASD and ADHD Traits in Typical Adults

Auteurs: Hilde M. Geurts, K. Richard Ridderinkhof, H. Steven Scholte

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 7/2013

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Abstract

We tested whether in 85 healthy adults (18–29 years) there is a relationship between grey-matter (GM) volume and autism and ADHD symptom severity. The structural MRI findings and autism and ADHD self-reports revealed that autism and ADHD symptom severity was correlated with GM volume in the left inferior frontal gyrus. Autism symptom-severity was correlated with the left posterior cingulate, ADHD with the right parietal lobe, right temporal frontal cortex, bilateral thalamus, and left hippocampus/amygdala complex. Symptom severity of both disorders form a continuum extending into the general population, but it seems to be an oversimplification to typify psychiatric disorders such as autism and ADHD solely as extremes of brain structure abnormalities.
Voetnoten
1
The results of these three ASD meta-analyses largely converged, but there were differences with respect to whether the left, right or bilateral sections of specific brain areas were deviant. If there were differences between the meta-analyses with respect to the location in either of the hemispheres we did mention a specific hemisphere.
 
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Metagegevens
Titel
The Relationship Between Grey-Matter and ASD and ADHD Traits in Typical Adults
Auteurs
Hilde M. Geurts
K. Richard Ridderinkhof
H. Steven Scholte
Publicatiedatum
01-07-2013
Uitgeverij
Springer US
Gepubliceerd in
Journal of Autism and Developmental Disorders / Uitgave 7/2013
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI
https://doi.org/10.1007/s10803-012-1708-4