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Although the conception of autism as a disorder of abnormal resting-state physiology has a long history, the evidence remains mixed. Using state-of-the-art eye-tracking pupillometry, resting-state (tonic) pupil size was measured in children with and without autism. No group differences in tonic pupil size were found, and tonic pupil size was not related to age or cognitive ability in either group, and nor was it related to autistic symptoms. We suggest that previous findings of hyper-arousal in autism at baseline may be a product of different recording methods, in particular different movement-artifact removal techniques. These results question the notion that autism is associated with a fundamental dysregulation in resting-state physiology. Further research, employing such techniques is needed to confirm these findings.
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American Psychiatric Association. (2000). Diagnostic and statistical manual of mental disorders, fourth edition (text revision): DSM-IV-TR. Washington, DC: American Psychiatric Publishing Inc. CrossRef
American Psychiatric Association. (2013). Diagnostic and statistical manual of mental disorders, fifth edition: DSM-5. Washington, DC: American Psychiatric Publishing.
Blair, R. (1999). Psychophysiological responsiveness to the distress of others in children with autism. Personality and Individual Differences, 26, 477–485. CrossRef
Chau, M., & Betke, M. (2005). Real time eye tracking and blink detection with USB cameras (Technical Report). Boston University Computer Science Department. Retrieved from http://dcommon.bu.edu/xmlui/handle/2144/1839.
Daluwatte, C., Miles, J., Christ, S., Beversdorf, D., Takahashi, T., & Yao, G. (2012). Atypical pupillary light reflex and heart-rate variability in children with autism spectrum disorder. Journal of Autism and Developmental Disorders. doi: 10.1007/s10803-012-1741-3.
Dykens, E., & Lense, M. (2011). Intellectual disabilities and autism spectrum disorder: A cautionary note. In D. Amaral, G. Dawson, & D. Geschwind (Eds.), Autism spectrum disorders. Oxford: Oxford University Press.
Goodwin, M. S., Groden, J., Velicer, W. F., Lipsitt, L. P., Baron, M. G., Hofmann, S. G., et al. (2006). Cardiovascular arousal in individuals with autism. Focus on Autism and Other Developmental Disabilities, 21(2), 100–123. CrossRef
Loewenfeld, I. E., & Lowenstein, O. (1993). The pupil: Anatomy, physiology, and clinical applications. Iowa State University Press Iowa. Retrieved from http://www.getcited.org/pub/102864797.
Lord, C., Rutter, M., DiLavore, P., & Risi, S. (1999). Autism diagnostic observation schedule-WPS. Los Angeles, CA: Western Psychological Services.
Mullen, E. (1995). Mullen scales of early learning. Circle Pines, MN: American Guidance Service.
Porges, S., Macellaio, M., Stanfill, S., McCue, K., Lewis, G., Harden, E., et al. (2012). Respiratory sinus arrhythmia and auditory processing in autism: Modifiable deficits of an integrated social engagement system? International Journal of Psychophysiology. doi: 10.1016/j.ijpsycho.2012.11.009. PubMedCentralPubMed
Stern, R., Ray, W., & Quigley, K. (2001). Psychophysiological recording (2nd ed.). New York: Oxford University Press.
Tabachnick, B. G., & Fidell, L. S. (1996). Using multiple statistics. New York: Harper Collins Publishers.
Van Hecke, A., Lebow, J., Bal, E., Lamb, D., Harden, E., Kramer, A., et al. (2009). Electroencephalogram and heart-rate regulation to familiar and unfamiliar people in children with autism spectrum disorders. Child Development, 80(4), 1118–1133. CrossRef
Waterhouse, L. (2012). Rethinking autism: Variation and complexity. London: Academic Press.
- Brief Report: Evidence for Normative Resting-State Physiology in Autism
Heather J. Nuske
- Springer US