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Journal of Autism and Developmental Disorders

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01-10-2007 | Original paper

Autistic Spectrum Disorders in Velo-cardio Facial Syndrome (22q11.2 Deletion)

Auteurs: Kevin M. Antshel, Alka Aneja, Leslie Strunge, Jena Peebles, Wanda P. Fremont, Kimberly Stallone, Nuria AbdulSabur, Anne Marie Higgins, Robert J. Shprintzen, Wendy R. Kates

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 9/2007

Abstract

The extent to which the phenotype of children comorbid for velocardiofacial syndrome (VCFS) and autism spectrum disorders (ASD) differs from that of VCFS-only has not been studied. The sample consisted of 41 children (20 females) with VCFS, ranging in age from 6.5 years to 15.8 years. Eight children with VCFS met formal DSM-IV diagnostic criteria for autism based upon the ADI-R. These eight plus an additional nine participants met diagnostic criteria for an autistic spectrum disorder (VCFS + ASD). Ninety-four percent of the children with VCFS + ASD had a co-occurring psychiatric disorder while 60% of children with VCFS had a psychiatric disorder. Children with VCFS + ASD had larger right amygdala volumes. All other neuroanatomic regions of interest were statistically similar between the two groups.

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Titel: Autistic Spectrum Disorders in Velo-cardio Facial Syndrome (22q11.2 Deletion)
Auteurs: Kevin M. Antshel
Alka Aneja
Leslie Strunge
Jena Peebles
Wanda P. Fremont
Kimberly Stallone
Nuria AbdulSabur
Anne Marie Higgins
Robert J. Shprintzen
Wendy R. Kates
Publicatiedatum: 01-10-2007
Uitgeverij: Springer US
Gepubliceerd in: Journal of Autism and Developmental Disorders / Uitgave 9/2007
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI: https://doi.org/10.1007/s10803-006-0308-6

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