Top

Journal of Autism and Developmental Disorders

Tip

Swipe om te navigeren naar een ander artikel

Gepubliceerd in:

01-10-2007 | Original Paper

The Broad Autism Phenotype Questionnaire

Auteurs: Robert S. E. Hurley, Molly Losh, Morgan Parlier, J. Steven Reznick, Joseph Piven

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 9/2007

Abstract

The broad autism phenotype (BAP) is a set of personality and language characteristics that reflect the phenotypic expression of the genetic liability to autism, in non-autistic relatives of autistic individuals. These characteristics are milder but qualitatively similar to the defining features of autism. A new instrument designed to measure the BAP in adults, the Broad Autism Phenotype Questionnaire (BAPQ), was administered to 86 parents of autistic individuals and 64 community control parents. Sensitivity and specificity of the BAPQ for detecting the BAP were high (>70%). Parents of children with autism had significantly higher scores on all three subscales: aloof personality, rigid personality, and pragmatic language. This instrument provides a valid and efficient measure for characterizing the BAP.

vorige artikel Imitation of Intentional and Accidental Actions by Children with Autism

volgende artikel A Parent-Report Instrument for Identifying One-Year-Olds at Risk for an Eventual Diagnosis of Autism: The First Year Inventory

Alleen toegankelijk voor geautoriseerde gebruikers

American Psychiatric Association (1994). Diagnostic and statistical manual of mental disorders (DSM-IV) (4th ed). Washington, DC: American Psychiatric Association.

Bailey, A., Le Couteur, A., Gottesman, I., Bolton, P., Simonoff, E., Yuzda, E., et al. (1995). Autism as a strongly genetic disorder: Evidence from a British Twin Study. Psychological Medicine, 25, 63–77. PubMedCrossRef

Baron-Cohen, S., Wheelwright, S., Skinner, R., Martin, J., & Clubley, E. (2001). The Autism-Spectrum quotient (AQ): Evidence from Asperger syndrome/high-functioning autism, males and females, scientists and mathematicians. Journal of Autism and Developmental Disorders, 31, 5–17. PubMedCrossRef

Bishop, D. V. M., Mayberry, M., Maley, A., Wong, D., Hill, W., & Hallmayer, J. (2004). Using self-report to identify the broad phenotype in parents of children with autistic spectrum disorders: A study using the Autism-Spectrum quotient. Journal of Child Psychology and Psychiatry, 45, 1431–1436. PubMedCrossRef

Bolton, P., Macdonald, H., Pickles, A., Rios, P., Goode, S., Crowson, M., Bailey, A., & Rutter, M. (1994). A case–control family history study of autism. Journal of Child Psychology and Psychiatry, 35, 877–900. PubMedCrossRef

Bradford, Y., Haines, J., Hutcheson, H., Gardiner, M., Braun, T., Sheffield, V., Cassavant, T., Huang, W., Wang, K., Vieland, V., Folstein, S., Santangelo, S., & Piven, J. (2001). Incorporating language phenotypes strengthens evidence of linkage to autism. American Journal of Medical Genetics-Neuropsychiatric Genetics, 105, 539–547. PubMedCrossRef

Constantino, J. N. (2002). The social responsiveness scale. Los Angeles, CA: Western Psychological Services.

Constantino, J. N., Lajonchere, C., Lutz, M., Gray, T., Abbachi, A., McKenna, K., Singh, D., & Todd, R. D. (2006). Autistic social impairment in the siblings of children with pervasive developmental disorders. American Journal of Psychiatry, 163, 294–296. PubMedCrossRef

Constantino, J. N., & Todd, R. D. (2005). Intergenerational transmission of subthreshold autistic traits in the general population. Biological Psychiatry, 57, 655–660. PubMedCrossRef

Folstein, S., & Rutter, M. (1977). Infantile autism: A genetic study of 21 twin pairs. Journal of Child Psychology and Psychiatry, 18, 297–321. PubMedCrossRef

Hyler, S. E., Rieder, R. O., Williams, J. B., Spitzer, R. L., Lyons, M., & Hendler, J. (1989). A comparison of clinical and self-report diagnoses of DSM-III personality disorders in 552 patients. Comprehensive Psychiatry, 30, 170–178. PubMedCrossRef

Kanner, L. (1943). Autistic disturbances of affective content. Nervous Child, 2, 217–250.

Landa, R., Piven, J., Wzorek, M. M., Gayle, J. O., Chase, G. A., Folstein, S. E. (1992). Social language usage in parents of autistic individuals. Psychological Medicine, 46, 245–254.

Le Couteur, A., Rutter, M., Lord, C., Rios, P., Robertson, P., Holdgrafer, M., & McLennan, J. (1989). Autism Diagnostic Interview: A standard investigator-based instrument. Journal of Autism and Developmental Disorders, 19, 363–387. PubMedCrossRef

Lord, C., Rutter, M., DiLavore, P., & Risi, S. (2006). Autism diagnostic observation schedule. San Antonio, TX: Western Psychological Services.

Lord, C., Rutter, M., Goode, S., Heemsbergen, J., Jordan, H., Mawhood, L., & Schopler, E. (1989). Autism diagnostic observation schedule: A standardized observation of communicative and social behavior. Journal of Autism and Developmental Disorders, 19, 185–212. PubMedCrossRef

Lord, C., Rutter, M., & Le Couteur, A. (1994). Autism diagnostic interview-revised: A revised version of a diagnostic interview for caregivers of individuals with possible pervasive developmental disorders. Journal of Autism and Developmental Disorders, 24, 659–685. PubMedCrossRef

Losh, M., & Piven, J. (2006). Social cognition and the broad autism phenotype: Identifying genetically meaningful phenotypes. Journal of Child Psychology and Psychiatry. In press.

Perry, J. C. (1992). Problems and considerations in the valid assessment of personality disorders. American Journal of Psychiatry, 149, 1645–1653. PubMed

Piven, J., Palmer, P., Jacobi, D., Childress, D., & Arndt, S. (1997). Broader autism phenotype: Evidence from a family history study of multiple-incidence autism families. American Journal of Psychiatry, 154, 185–190. PubMed

Piven, J., Palmer, P., Landa, R., Santangelo, S., Jacobi, D., & Childress, C. (1997). Personality and language characteristics in parents from multiple-incidence autism families. American Journal of Medical Genetics, 74, 398–411. PubMedCrossRef

Piven, J., Wzorek, M., Landa, R., Lainhart, J., Bolton, P., Chase, G. A., & Folstein, S. (1994). P`ersonality characteristics of the parents of autistic individuals. Psychological Medicine, 24, 783–795. PubMed

Sung, Y. J., Dawson, G., Munson, J., Estes, A., Schellenberg, G. D., & Wijsman, E. M. (2005). Genetic investigation of quantitative traits related to autism: Use of multivariate polygenic models with ascertainment adjustment. American Journal of Human Genetics, 76, 68–81. PubMedCrossRef

Tyrer, P., & Alexander, J. (1979). Classification of personality disorder. British Journal of Psychiatry, 135, 163–167. PubMedCrossRef

Titel: The Broad Autism Phenotype Questionnaire
Auteurs: Robert S. E. Hurley
Molly Losh
Morgan Parlier
J. Steven Reznick
Joseph Piven
Publicatiedatum: 01-10-2007
Uitgeverij: Springer US
Gepubliceerd in: Journal of Autism and Developmental Disorders / Uitgave 9/2007
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI: https://doi.org/10.1007/s10803-006-0299-3

Mijn bibliotheek

Shop

Tips voor Mijn BSL

Bohn Stafleu van Loghum

Tip

Swipe om te navigeren naar een ander artikel

The Broad Autism Phenotype Questionnaire

Abstract

Mijn bibliotheek

Shop

Tips voor Mijn BSL

Bohn Stafleu van Loghum

Tip

Swipe om te navigeren naar een ander artikel

Deel dit onderdeel of sectie (kopieer de link)

Abstract

Log in om toegang te krijgen

Andere artikelen Uitgave 9/2007

Disparities in Diagnoses Received Prior to a Diagnosis of Autism Spectrum Disorder

Factor Structure Evaluation of the Childhood Autism Rating Scale

A Parent-Report Instrument for Identifying One-Year-Olds at Risk for an Eventual Diagnosis of Autism: The First Year Inventory

Brief Report: Relative Effectiveness of Different Home-based Behavioral Approaches to Early Teaching Intervention

The Problem with Using Eye-Gaze to Infer Desire: A Deficit of Cue Inference in Children with Autism Spectrum Disorder?

Change in Autism Symptoms and Maladaptive Behaviors in Adolescents and Adults with an Autism Spectrum Disorder