Swipe om te navigeren naar een ander artikel
This study examined the differential contribution of pre- and perinatal risks in narrowly versus broadly defined autism spectrum disorder (ASD) and across core symptom domains, IQ and co-morbid problems. Children with a DSM-IV diagnosis of autistic disorder (AD) (n = 121) or pervasive developmental disorder not otherwise specified (PDD-NOS) (n = 75) were compared to a typical control sample (n = 311). Diagnoses were based on extensive assessments between 12 and 49 months of age (M = 33.3, SD = 6.4) and re-evaluated at 43–98 months (M = 68.1, SD = 10.7) in 70 % of the cases. Compared with controls, cases with ASD were more likely to be firstborn and show a suboptimal condition after birth. Case mothers reported more infections and more stress during pregnancy. Although the ASD subgroups showed mostly overlapping risks, cases with PDD-NOS differed from those with AD by higher exposure to smoking during pregnancy (SDP) and by a negative association of smoking with IQ, regardless of confounders. SDP appears to contribute more to broadly defined (PDD-NOS) than to narrowly defined ASD (AD). Findings suggest differences in etiological contributors between ASD phenotypes.
Log in om toegang te krijgen
Met onderstaand(e) abonnement(en) heeft u direct toegang:
Achenbach, T. M., & Rescorla, L. A. (2000). Manual for ASEBA preschool forms & profiles. Burlington, VT: University of Vermont, Research Center for Children, Youth, & Families.
American Psychiatric Association. (2000). Diagnostic and statistical manual of mental disorders, Fourth Edition, Text Revision. Washington, DC: American Psychiatric Association. CrossRef
Bill, B. R., & Geschwind, D. H. (2009). Genetic advances in autism: Heterogeneity and convergence on shared pathways. Current Opinion in Genetics & Development, 19(3), 271–278. CrossRef
Constantino, J. N., & Todd, R. D. (2008). Genetic epidemiology of pervasive developmental disorders. In: J. J. Hudziac (Ed.), Developmental psychopatholgy and wellness: Genetic and environmental influences. American Psychiatric Publishing, Inc: Arlington.
Deb, S., Prasad, K. B., Seth, H., & Eagles, J. M. (1997). A comparison of obstetric and neonatal complications between children with autistic disorder and their siblings. Journal of Intellectual Disability Research, 41(Pt 1), 81–86. PubMed
Georgiades, S., Szatmari, P., Duku, E., Zwaigenbaum, L., Bryson, S., Roberts, W., et al. (2011). Phenotypic overlap between core diagnostic features and emotional/behavioral problems in preschool children with autism spectrum disorder. Journal of Autism and Developmental Disorders, 41(10), 1321–1329. PubMedCrossRef
Gibbs, V., Aldridge, F., Chandler, F., Witzlsperger, E., & Smith, K. (2012). Brief report: An exploratory study comparing diagnostic outcomes for autism spectrum disorders under DSM-IV-TR with the proposed DSM-5 revision. Journal of Autism and Developmental Disorders, 42(8), 1750–1756. PubMedCrossRef
Heath, A. C., Knopik, V. S., Madden, P. A., Neuman, R. J., Lynskey, M. J., Slutske, W. S., et al. (2003). Accuracy of mothers’ retrospective reports of smoking during pregnancy: Comparison with twin sister informant ratings. Twin Research, 6(4), 297–301. PubMed
Hoekstra, R. A., Happe, F., Baron-Cohen, S., & Ronald, A. (2010). Limited genetic covariance between autistic traits and intelligence: Findings from a longitudinal twin study. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics, 153B(5), 994–1007.
Holm, S. (1979). A simple sequentially rejective multiple test procedure. Scandinavian Journal of Statistics, 6, 65–70.
Kalkbrenner, A. E., Braun, J. M., Durkin, M. S., Maenner, M. J., Cunniff, C., Lee, L. C., et al. (2012). Maternal smoking during pregnancy and the prevalence of autism spectrum disorders using data from the autism and developmental disabilities monitoring network. Environmental Health Perspectives, 120(7), 1042–1048. PubMedCrossRef
Lee, B. K., Gardner, R. M., Dal, H., Svensson, A., Galanti, M. R., Rai, D., et al. (2011). Brief report: Maternal smoking during pregnancy and autism spectrum disorders. Journal of Autism and Developmental Disorders, 42(9), 2000–2005. CrossRef
Lord, C., Rutter, M., DiLavore, P., & Risi, S. (2001). Autism diagnostic observation schedule (ADOS) manual. Los Angeles, CA: Western Psychological Services.
Matson, J. L., Hattier, M. A., & Williams, L. W., (2012a). How does relaxing the algorithm for autism affect DSM-V prevalence rates? Journal of Autism and Developmental Disorders, 42(8), 1549–1556.
Matson, J. L., Kozlowski, A. M., Hattier, M. A., Horovitz, M., & Sipes, M., (2012b). DSM-IV vs DSM-5 diagnostic criteria for toddlers with autism. Developmental Neurorehabilitation, 15(3), 185–190.
Matson, J. L., Mahan, S., Fodstad, J. C., Worley, J. A., Neal, D., & Sipes, M. (2011). Effects of symptoms of co-morbid psychopathology on challenging behaviours among infants and toddlers with autistic disorder and PDD-NOS as assessed with the Baby and Infant Screen for Children with aUtIsm Traits (BISCUIT). Developmental neurorehabilitation, 14(3), 129–139. PubMedCrossRef
Mullen, E. (1995). Mullen scales of early learning (AGS Edition ed). Circle Pines, MN: American Guidance Service.
Oosterling, I. J., Wensing, M., Swinkels, S. H., van der Gaag, R. J., Visser, J. C., Woudenberg, T., et al. (2010). Advancing early detection of autism spectrum disorder by applying an integrated two-stage screening approach. Journal of Child Psychology and Psychiatry, 51(3), 250–258.
Reiersen, A. M., & Todorov, A. A. (2011). Association between DRD4 genotype and autistic symptoms in DSM-IV ADHD. Journal of the Canadian Academy of Child and Adolescent Psychiatry, 20(1), 15–21. PubMed
Robinson, E. B., Koenen, K. C., McCormick, M. C., Munir, K., Hallett, V., Happe, F., et al. (2011a). Evidence that autistic traits show the same etiology in the general population and at the quantitative extremes (5 %, 2.5 %, and 1 %). Archives of General Psychiatry, 68(11), 1113–1121. PubMedCrossRef
Ronald, A., Pennell, C. E., & Whitehouse, A. J. (2010c). Prenatal maternal stress associated with ADHD and autistic traits in early childhood. Frontiers in Psychology, 1, 223. PubMed
Rutter, M., Le Couteur, A., & Lord, C. (2003). ADI-R: Autism diagnostic interview-revised. Los Angeles, CA: Western Psychological Services.
Schopler, E., Reichler, R. J., Bashford, A., Lansing, M. D., & Marcus, L. M. (1990). The psychoeducational profile revised (PEP-R). Austin: Pro-Ed.
Simonoff, E., Pickles, A., Charman, T., Chandler, S., Loucas, T., & Baird, G. (2008). Psychiatric disorders in children with autism spectrum disorders: Prevalence, comorbidity, and associated factors in a population-derived sample. Journal of the American Academy of Child and Adolescent Psychiatry, 47(8), 921–929. PubMedCrossRef
Swinkels, S. H., Dietz, C., van Daalen, E., Kerkhof, I. H., van Engeland, H., & Buitelaar, J. K. (2006). Screening for autistic spectrum in children aged 14 to 15 months. I: The development of the Early Screening of Autistic Traits Questionnaire (ESAT). Journal of Autism and Developmental Disorders, 36(6), 723–732. PubMedCrossRef
Todd, R. D., & Neuman, R. J. (2007). Gene-environment interactions in the development of combined type ADHD: Evidence for a synapse-based model. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics, 144B(8), 971–975. CrossRef
van Daalen, E., Kemner, C., Dietz, C., Swinkels, S. H., Buitelaar, J. K., & van Engeland, H. (2009). Inter-rater reliability and stability of diagnoses of autism spectrum disorder in children identified through screening at a very young age. European Child and Adolescent Psychiatry, 18(11), 663–674. PubMedCrossRef
Yerys, B. E., Wallace, G. L., Sokoloff, J. L., Shook, D. A., James, J. D., & Kenworthy, L. (2009). Attention deficit/hyperactivity disorder symptoms moderate cognition and behavior in children with autism spectrum disorders. Autism Research, 2(6), 322–333. PubMed
- Narrowly Versus Broadly Defined Autism Spectrum Disorders: Differences in Pre- and Perinatal Risk Factors
Janne C. Visser
Iris J. Oosterling
Rutger J. van der Gaag
Jan K. Buitelaar
- Springer US