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Journal of Autism and Developmental Disorders

Gepubliceerd in:

01-09-2008 | Original Paper

Obstetric and Parental Psychiatric Variables as Potential Predictors of Autism Severity

Auteurs: Anna E. Wallace, George M. Anderson, Robert Dubrow

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 8/2008

Abstract

Associations between obstetric and parental psychiatric variables and subjects’ Autism Diagnostic Interview-Revised (ADI-R) and Autism Diagnostic Observation Schedule (ADOS) domain scores were examined using linear mixed effects models. Data for the 228 families studied were provided by the Autism Genetic Resource Exchange. Hypertension (P = 0.002), preeclampsia (P = 0.021) and generalized edema (P = 0.011) were associated with higher ADI-R communication scores. Hypertension (P = 0.011), albuminuria (P = 0.039) and generalized edema (P = 0.009) were associated with higher ADI-R repetitive behaviors scores. Parent depression was associated with higher ADI-R repetitive behaviors scores (P = 0.005), and parent anxiety with lower ADOS social/communication composite scores (P = 0.025). The associations between hypertension-related obstetric conditions and autistic severity warrant further investigation and raise intriguing questions regarding potential causal and modifying factors in autism.

vorige artikel The ‘Reading the Mind in Films’ Task [Child Version]: Complex Emotion and Mental State Recognition in Children with and without Autism Spectrum Conditions

volgende artikel Factor Structure, Reliability and Criterion Validity of the Autism-Spectrum Quotient (AQ): A Study in Dutch Population and Patient Groups

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Titel: Obstetric and Parental Psychiatric Variables as Potential Predictors of Autism Severity
Auteurs: Anna E. Wallace
George M. Anderson
Robert Dubrow
Publicatiedatum: 01-09-2008
Uitgeverij: Springer US
Gepubliceerd in: Journal of Autism and Developmental Disorders / Uitgave 8/2008
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI: https://doi.org/10.1007/s10803-007-0536-4

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