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30-07-2018 | Original Paper | Uitgave 5/2020 Open Access

Journal of Autism and Developmental Disorders 5/2020

Longitudinal Epidemiological Study of Autism Subgroups Using Autism Treatment Evaluation Checklist (ATEC) Score

Tijdschrift:
Journal of Autism and Developmental Disorders > Uitgave 5/2020
Auteurs:
Shreyas Mahapatra, Edward Khokhlovich, Samantha Martinez, Benjamin Kannel, Stephen M. Edelson, Andrey Vyshedskiy
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Electronic supplementary material

The online version of this article (https://​doi.​org/​10.​1007/​s10803-018-3699-2) contains supplementary material, which is available to authorized users.

Abstract

Here we report the results of the subgroup analyses of an observational cohort of children whose parents completed the Autism Treatment Evaluation Checklist (ATEC) over the period of several years. A linear mixed effects model was used to evaluate longitudinal changes in ATEC scores within different patient subgroups. All groups decreased their mean ATEC score over time indicating improvement of symptoms, however there were significant differences between the groups. Younger children improved more than the older children. Children with milder ASD improved more than children with more severe ASD in the Communication subscale. There was no difference in improvement between females vs. males. One surprising finding was that children from developed English-speaking countries improved less than children from non-English-speaking countries.

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