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Gepubliceerd in: Journal of Autism and Developmental Disorders 2/2022

07-04-2021 | Original Paper

Moderators of Response to Personalized and Standard Care Cognitive-Behavioral Therapy for Youth with Autism Spectrum Disorder and Comorbid Anxiety

Auteurs: Eric A. Storch, Jeffrey J. Wood, Andrew G. Guzick, Brent J. Small, Connor M. Kerns, D. Luis Ordaz, Sophie C. Schneider, Philip C. Kendall

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 2/2022

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Abstract

Anxiety/obsessive-compulsive disorders are common among youth with autism spectrum disorder (ASD). Two versions of cognitive behavior therapy (CBT) are effective, with some advantage for a personalized, adapted version. This study evaluated predictors and moderators of standard CBT and adapted CBT. Youth (N = 167) ages 7–13 were randomized to standard or adapted CBT, or treatment-as-usual. Age, IQ, ASD severity, and emotional-behavioral symptom severity were examined. More severe internalizing and emotional-behavioral problems predicted poorer treatment outcomes especially in standard versus personalized CBT. Elevated repetitive behaviors and restricted interests predicted poorer treatment outcomes across treatments, though youth with “moderate” repetitive behaviors and restricted interested experienced poorer outcomes only in standard but not personalized CBT. Externalizing symptoms directly predicted treatment outcomes. Older age predicted improved outcomes in adapted but not standard CBT. Findings highlight the need for further treatment refinements and the value in adapting treatment for youth with more complex presentations. Trial Registration Clinicialtrials.gov: NCT02028247; https://​clinicaltrials.​gov/​ct2/​show/​NCT02028247.
Voetnoten
1
To ensure that this age*condition interaction was not a by-product of increased symptom severity that is sometimes associated with older age, correlations were conducted between CBCL-Internalizing, Externalizing, and Total Problems and age, failing to find significant relationships (rs < .03). Analyses also controlled for baseline anxiety severity.
 
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Metagegevens
Titel
Moderators of Response to Personalized and Standard Care Cognitive-Behavioral Therapy for Youth with Autism Spectrum Disorder and Comorbid Anxiety
Auteurs
Eric A. Storch
Jeffrey J. Wood
Andrew G. Guzick
Brent J. Small
Connor M. Kerns
D. Luis Ordaz
Sophie C. Schneider
Philip C. Kendall
Publicatiedatum
07-04-2021
Uitgeverij
Springer US
Gepubliceerd in
Journal of Autism and Developmental Disorders / Uitgave 2/2022
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI
https://doi.org/10.1007/s10803-021-05000-0

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