Journal of the American Academy of Child & Adolescent Psychiatry
New researchClinical Predictors of Response to Cognitive-Behavioral Therapy in Pediatric Anxiety Disorders: The Genes for Treatment (GxT) Study
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This article was reviewed under and accepted by deputy editor John Piacentini, PhD.
Combined study supported by UK MRC grant G0901874/1 (T.C.E.). Individual trials support by Australian Research Council grant DP0878609 (J.L.H., Jenny Donald, PhD, R.M.R., T.C.E.); Australian National Health and Medical Research Council grants (1027556: R.M.R., J.L.H., H.J.L., Cathy Mihalopolous, BSc[Hons], PhD), (488505: H.J.L., J.L.H., R.M.R.), and (382008: J.L.H. and R.M.R.); TrygFonden grant (7-10-1391: M.T. and Esben Hougaard, PhD); Edith og Godtfred Kirk Christiansens Fond grant (21-5675: M.T.); Swiss National Science Foundation grant (105314-116517: S.S.); Western Norway Regional Health Authority grants (911253: Odd E. Havik, PhD) and (911366: E.H.); UK MRC Clinical Fellowship (G0802821: R.M.-S.); National Institute of Mental Health R01MH079943 (W.K.S.); UK National Institute for Health Research (NIHR) grants (PB-PG-0110-21190: C.C.) and (PB-PG-0107-12042: P.C.); UK MRC grants (09-800-17: P.C. and C.C.; G0802326: K.T., P.C., and C.C.; G1002011: P.W., C.C., and P.C.; and G0601874; C.C.). Grant 09-800-17 was managed by NIHR on behalf of the MRC-NIHR partnership. Dr. Lester is supported by an MRC research grant (MR/J011762/1) and Jacobs Foundation Young Scholar Award. Dr. Keers is supported by an MRC Population Health Scientist Award (MR/K021281/1). This study presents independent research partly funded by the NIHR Biomedical Research Centre at South London and Maudsley, NHS Foundation Trust, and King’s College London. The views expressed are those of the author(s) and not necessarily those of the NHS, the NIHR, or the Department of Health.
Drs. Hudson and Keers contributed equally to the work. Drs. Lester and Eley also contributed equally to the work.
Dr. Keers served as the statistical expert for this research.
Disclosure: Dr. Hudson is an author of the Cool Kids program but receives no direct payment from it. Dr. Creswell is joint author of a book used in treatment within the Overcoming trial and receives royalties from sales of the book. Dr. Lyneham is an author of the Cool Kids program but receives no direct payment from it. Dr. Rapee is an author of the Cool Kids program but receives no direct payment from it. Dr. Schneider is an author of the Diagnostisches Interview bei psychischen Störungen im Kindes- und Jugendalter, from which she receives royalties. Dr. Silverman is an author of the Anxiety Disorders Interview Schedule for Children, from which she receives royalties. Drs. Keers, Breen, Arendt, Bogels, Cooper, Hartman, Heiervang, Hötzel, In-Albon, Lavallee, Marin, McKinnon, Meiser-Stedman, Nauta, Thastum, Thirlwall, Waite, Wergeland, Lester, Eley, Ms. Roberts, Mr. Coleman, Ms. Morris, and Ms. Schneider report no biomedical financial interests or potential conflicts of interest.