Skip to main content
main-content
Top

Tip

Swipe om te navigeren naar een ander artikel

13-05-2016 | Original Paper | Uitgave 8/2016 Open Access

Journal of Autism and Developmental Disorders 8/2016

Gray Matter Characteristics in Mid and Old Aged Adults with ASD

Tijdschrift:
Journal of Autism and Developmental Disorders > Uitgave 8/2016
Auteurs:
P. Cédric M. P. Koolschijn, Hilde M. Geurts
Belangrijke opmerkingen

Electronic supplementary material

The online version of this article (doi:10.​1007/​s10803-016-2810-9) contains supplementary material, which is available to authorized users.

Abstract

It is widely acknowledged that the brain anatomy of children and adolescents with autism spectrum disorder (ASD) shows a different developmental pattern then typical age-matched peers. There is however, a paucity of studies examining gray matter in mid and late adulthood in ASD. In this cross-sectional neuroimaging study, we, performed vertex-wise whole-brain and region-of-interest analyses of cortical volume, thickness, surface area, and gyrification index in 51 adults with and 49 without ASD, between 30 and 75 years. There was significant age-related volume loss and cortical thinning, but there were no group differences. The lack of significant anatomical differences between intellectual able individuals with and without ASD, suggests that ASD is not (strongly) related to gray matter morphology in mid and late adulthood.

Onze productaanbevelingen

BSL Psychologie Totaal

Met BSL Psychologie Totaal blijft u als professional steeds op de hoogte van de nieuwste ontwikkelingen binnen uw vak. Met het online abonnement heeft u toegang tot een groot aantal boeken, protocollen, vaktijdschriften en e-learnings op het gebied van psychologie en psychiatrie. Zo kunt u op uw gemak en wanneer het u het beste uitkomt verdiepen in uw vakgebied.

Extra materiaal
Fig. S1 Supplementary material 1 (TIFF 9108 kb)
10803_2016_2810_MOESM1_ESM.tif
Table S1 Demographic variables ABIDE data set (DOCX 86 kb)
10803_2016_2810_MOESM2_ESM.docx
Table S2 Lobar regression analyses for all morphometric measures ADOS-only (DOCX 98 kb)
10803_2016_2810_MOESM3_ESM.docx
Table S3 Lobar regression analyses for all morphometric measures including ABIDE sample (total N=177) (DOCX 103 kb)
10803_2016_2810_MOESM4_ESM.docx
Table S4 Volumes of cortical and subcortical brain structures ADOS-only (DOCX 65 kb)
10803_2016_2810_MOESM5_ESM.docx
Table S5 Volumes of cortical and subcortical brain structures including ABIDE sample (total N=177) (DOCX 99 kb)
10803_2016_2810_MOESM6_ESM.docx
Doc S Supplemental Material ABIDE. Description, Methods and Results (DOCX 94 kb)
10803_2016_2810_MOESM7_ESM.docx
Literatuur
Over dit artikel

Andere artikelen Uitgave 8/2016

Journal of Autism and Developmental Disorders 8/2016 Naar de uitgave