Swipe om te navigeren naar een ander artikel
Portions of this data has been presented at the International Meeting For Autism Research 2017 (San Francisco, CA) and 2018 (Rotterdam, Netherlands), the NIH Future Research Leaders Conference (Bethesda, MD) and the Triangle Neuroscience Conference (Raleigh, NC).
Recent studies suggest that circumscribed interests (CI) in females with Autism Spectrum Disorder (ASD) may align more closely with interests reported in typical female development than those typically reported for ASD males. We used eye-tracking to quantify attention to arrays containing combinations of male, female and neutral images in elementary-aged males and females with and without ASD. A number of condition × sex effects emerged, with both groups attending to images that corresponded with interests typically associated with their biological sex. Diagnostic effects reported in similar studies were not replicated in our modified design. Our findings of more typical attention patterns to gender-typical images in ASD females is consistent with evidence of sex differences in CI and inconsistent with the “Extreme Male Brain” theory of ASD.
Log in om toegang te krijgen
Met onderstaand(e) abonnement(en) heeft u direct toegang:
Bargiela, S., Steward, R., & Mandy, W. (2016). The experiences of late-diagnosed women with autism spectrum conditions: An investigation of the female autism phenotype. Journal of Autism and Developmental Disorders, 46, 3281–3291. CrossRef
Baron-Cohen, S. (2002). The extreme male brain theory of autism. Trends in Cognitive Sciences, 6, 248–254. https://doi.org/10.1016/s1364-6613(02)01904-6. CrossRefPubMed
Baron-Cohen, S. (2009). Autism: The empathizing-systemizing (E-S) theory. Annals of the New York Academy of Sciences, 1156, 68–80. https://doi.org/10.1111/j.1749-6632.2009.04467.x. CrossRef
Bishop, S. L., Guthrie, W., Coffing, M., & Lord, C. (2011). Convergent validity of the Mullen Scales of Early Learning and the differential ability scales in children with autism spectrum disorders. American Journal on Intellectual and Developmental Disabilities, 116, 331–343. https://doi.org/10.1352/1944-7558-116.5.331. CrossRefPubMed
Bodfish, J. W. (2003). Interests Scale. Chapel Hill, NC.
Bodfish, J., Symons, F., & Lewis, M. (1999). The Repetitive Behavior Scale-Revised. Morganton: Western Carolina Center Research Reports.
Caldera, Y. M., Huston, A. C., & O’Brien, M. (1989). Social interactions and play patterns of parents and toddlers with feminine, masculine, and neutral toys. Child Development, 60(1), 70–76. CrossRef
Cherney, I. D., & London, K. (2006). Gender-linked differences in the toys, television shows, computer games, and outdoor activities of 5-to 13-year-old children. Sex Roles, 54(9–10), 717. CrossRef
Chevallier, C., Parish-Morris, J., McVey, A., Rump, K. M., Sasson, N. J., Herrington, J. D., et al. (2015). Measuring social attention and motivation in autism spectrum disorder using eye-tracking: Stimulus type matters. Autism Research, 8, 620–628. https://doi.org/10.1002/aur.1479. CrossRefPubMedPubMedCentral
Christensen, D. L., Baio, J., Van Naarden Braun, K., Bilder, D., Charles, J., Constantino, J. N., et al. (2016). Prevalence and characteristics of autism spectrum disorder among children aged 8 years–autism and developmental disabilities monitoring network, 11 sites, United States, 2012. MMWR Surveillance Summaries, 65, 1–23. https://doi.org/10.15585/mmwr.ss6503a1. CrossRef
DeLoache, J. S., Simcock, G., & Macari, S. (2007). Planes, trains, automobiles–and tea sets: Extremely intense interests in very young children. Developmental Psychology, 43, 1579–1586. https://doi.org/10.1037/0012-16220.127.116.119. CrossRefPubMed
Dworzynski, K., Ronald, A., Bolton, P., & Happe, F. (2012). How different are girls and boys above and below the diagnostic threshold for autism spectrum disorders? Journal of the American Academy of Child & Adolescent Psychiatry, 51, 788–797. https://doi.org/10.1016/j.jaac.2012.05.018. CrossRef
Elliot, C. D. (2007). Differential Ability Scales–second edition (DAS-II). San Antonio, TX: Pearson.
Fletcher-Watson, S., Leekam, S. R., Benson, V., Frank, M. C., & Findlay, J. M. (2009). Eye-movements reveal attention to social information in autism spectrum disorder. Neuropsychologia, 47, 248–257. https://doi.org/10.1016/j.neuropsychologia.2008.07.016. CrossRefPubMed
Foss-Feig, J. H., McGugin, R. W., Gauthier, I., Mash, L. E., Ventola, P., & Cascio, C. J. (2016). A functional neuroimaging study of fusiform response to restricted interests in children and adolescents with autism spectrum disorder. Journal of Neurodevelopmental Disorders, 8(1), 15. CrossRef
Frazier, T. W., Georgiades, S., Bishop, S. L., & Hardan, A. Y. (2014). Behavioral and cognitive characteristics of females and males with autism in the Simons Simplex Collection. Journal of the American Academy of Child & Adolescent Psychiatry, 53, 329–340. https://doi.org/10.1016/j.jaac.2013.12.004 ( e321–e323). CrossRef
Grelotti, D. J., Klin, A. J., Gauthier, I., Skudlarski, P., Cohen, D. J., Gore, J. C., et al. (2005). fMRI activation of the fusiform gyrus and amygdala to cartoon characters but not to faces in a boy with autism. Neuropsychologia, 43(3), 373–385. CrossRef
Klin, A., Danovitch, J. H., Merz, A. B., & Volkmar, F. R. (2007). Circumscribed interests in higher functioning individuals with autism spectrum disorders: An exploratory study. Research and Practice for Persons with Severe Disabilities, 32, 89–100. CrossRef
Koegel, R. L., Fredeen, R., Kim, S., Danial, J., Rubinstein, D., & Koegel, L. (2012). Using perseverative interests to improve interactions between adolescents with autism and their typical peers in school settings. Journal of Positive Behavior Interventions, 14, 133–141. https://doi.org/10.1177/1098300712437043. CrossRefPubMedPubMedCentral
Koenig, K. P., & Hough, L. W. (2017). Characterization and utilization of preferred interests: A survey of adults on the autism spectrum. Occupational Therapy in Mental Health, 33(2), 1–12. https://doi.org/10.1080/0164212x.2016.1248877. CrossRef
Lai, M. C., Lombardo, M. V., Auyeung, B., Chakrabarti, B., & Baron-Cohen, S. (2015). Sex/gender differences and autism: Setting the scene for future research. Journal of the American Academy of Child & Adolescent Psychiatry, 54, 11–24. https://doi.org/10.1016/j.jaac.2014.10.003. CrossRef
Lai, M. C., Lombardo, M. V., Pasco, G., Ruigrok, A. N., Wheelwright, S. J., Sadek, S. A., et al. (2011). A behavioral comparison of male and female adults with high functioning autism spectrum conditions. PLoS ONE, 6, e20835. https://doi.org/10.1371/journal.pone.0020835. CrossRefPubMedPubMedCentral
Lord, C., Risi, S., Lambrecht, L., Cook, J. E. H., Leventhal, B. L., DiLavore, P. C., et al. (2000). The autism diagnostic observation schedule—generic: A standard measure of social and communication deficits associated with the spectrum of autism. Journal of Autism and Developmental Disorders, 30, 205–223. https://doi.org/10.1023/a:1005592401947. CrossRef
Pierce, K., & Courchesne, E. (2001). Evidence for a cerebellar role in reduced exploration and stereotyped behavior in autism. Biological Psychiatry, 49, 655–664. https://doi.org/10.1016/s0006-3223(00)01008-8. CrossRefPubMed
Robinson, C. C., & Morris, J. T. (1986). The gender-stereotyped nature of christmas toys received by 36-, 48-, and 60-month-old children: A comparison between nonrequested vs requested toys. Sex Roles, 15(1–2), 21–32. CrossRef
Rutter, M., Bailey, A., & Lord, C. (2003a). The Social Communication Questionnaire. Los Angeles: Western Psychological Services.
Rutter, M., Le Couteur, A., & Lord, C. (2003b). ADI-R. Autism diagnostic interview revised. Los Angeles: Western Psychological Services.
Sasson, N. J., Dichter, G. S., & Bodfish, J. W. (2012). Affective responses by adults with autism are reduced to social images but elevated to images related to circumscribed interests. PLoS ONE, 7, e42457. https://doi.org/10.1371/journal.pone.0042457. CrossRefPubMedPubMedCentral
Schopler, E., Van Bourgondien, M. E., Wellman, G. J., & Love, S. R. (2010). Childhood Autism Rating Scale-(2nd edition). Los Angeles: Western Psychological Services.
Sedgewick, F., Hill, V., Yates, R., Pickering, L., & Pellicano, E. (2016). Gender differences in the social motivation and friendship experiences of autistic and non-autistic adolescents. Journal of Autism and Developmental Disorders, 46, 1297–1306. https://doi.org/10.1007/s10803-015-2669-1. CrossRefPubMed
Unruh, K. E., Sasson, N. J., Shafer, R. L., Whitten, A., Miller, S. J., Turner-Brown, L., et al. (2016). Social orienting and attention is influenced by the presence of competing nonsocial information in adolescents with autism. Frontiers in Neuroscience, 10, 586. https://doi.org/10.3389/fnins.2016.00586. CrossRefPubMedPubMedCentral
Van Wijngaarden-Cremers, P. J., van Eeten, E., Groen, W. B., Van Deurzen, P. A., Oosterling, I. J., & Van der Gaag, R. J. (2014). Gender and age differences in the core triad of impairments in autism spectrum disorders: A systematic review and meta-analysis. Journal of Autism and Developmental Disorders, 44, 627–635. https://doi.org/10.1007/s10803-013-1913-9. CrossRefPubMed
Vismara, L. A., & Lyons, G. L. (2016). Using perseverative interests to elicit joint attention behaviors in young children with autism. Journal of Positive Behavior Interventions, 9, 214–228. https://doi.org/10.1177/10983007070090040401. CrossRef
- Circumscribed Interests and Attention in Autism: The Role of Biological Sex
Brian A. Boyd
- Springer US