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This study explored the interrelationship between intolerance of uncertainty, sensory hyper-sensitivity and anxiety in Williams syndrome (WS). Thirty-two parents or guardians of individuals with WS (Mage = 24.76 years, SD = 7.55) were included. Associations between anxiety, intolerance of uncertainty, sensory hyper-sensitivity, and ASD symptoms were assessed. Linear regression analysis revealed that intolerance of uncertainty and sensory hyper-sensitivity were unique independent predictors of anxiety, while social communication score was not. There was evidence of a mediating effect of sensory hyper-sensitivity on the relationship between intolerance of uncertainty and anxiety. These findings bear strong resemblance to the pattern seen in ASD and emphasize the need for development of anxiety interventions that attempt to reduce negative beliefs about unpredictable situations in WS.
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Aron, E. N., Aron, A., & Jagiellowicz, J. (2012). Sensory processing sensitivity: A review in the light of the evolution of biological responsivity. Personality and Social Psychology Review, 16(3), 262–282. PubMed
Attwood, T. (1998). Asperger’s syndrome: A guide for parents and professionals. London: Jessica Kingsley Publishers.
Bellini, S. (2004). Social skill deficits and anxiety in high-functioning adolescents with autism spectrum disorders. Focus on Autism and Other Developmental Disabilities, 19(2), 78–86.
Bellini, S. (2006). The development of social anxiety in adolescents with autism spectrum disorders. Focus on Autism and Other Developmental Disabilities, 21(3), 138–145.
Boulter, C., Freeston, M., South, M., & Rodgers, J. (2014). Intolerance of uncertainty as a framework for understanding anxiety in children and adolescents with autism spectrum disorders. Journal of Autism and Developmental Disorders, 44(6), 1391–1402. PubMed
Brown, C., & Dunn, W. (2002). Adolescent-adult sensory profile: User’s manual. Tucson, AZ: Therapy Skill Builders.
Carleton, R. N., Duranceau, S., Shulman, E. P., Zerff, M., Gonzales, J., & Mishra, S. (2016). Self-reported intolerance of uncertainty and behavioural decisions. Journal of Behavior Therapy and Experimental Psychiatry, 51, 58–65. PubMed
Carleton, R. N., Mulvogue, M. K., Thibodeau, M. A., McCabe, R. E., Antony, M. M., & Asmundson, G. J. (2012). Increasingly certain about uncertainty: Intolerance of uncertainty across anxiety and depression. Journal of Anxiety Disorders, 26, 468–479. PubMed
Carleton, R. N., Norton, M. P. J., & Asmundson, G. J. (2007). Fearing the unknown: A short version of the Intolerance of Uncertainty Scale. Journal of Anxiety Disorders, 21(1), 105–117. PubMed
Cherniske, E. M., Carpenter, T. O., Klaiman, C., Young, E., Bregman, J., Insogna, K., et al. (2004). Multisystem study of 20 older adults with Williams syndrome. American Journal of Medical Genetics Part A, 131(3), 255–264. PubMed
Constantino, J. N., Davis, S. A., Todd, R. D., Schindler, M. K., Gross, M. M., Brophy, S. L., et al. (2003). Validation of a brief quantitative measure of autistic traits: Comparison of the social responsiveness scale with the autism diagnostic interview-revised. Journal of Autism and Developmental Disorders, 33(4), 427–433. PubMed
Davies, M., Udwin, O., & Howlin, P. (1998). Adults with Williams syndrome. Preliminary study of social, emotional and behavioural difficulties. British Journal of Psychiatry, 172(3), 273–276. PubMed
Davis, T. E., III, White, S. W., & Ollendick, T. H. (2014). Handbook of autism and anxiety. New York: Springer.
Dykens, E. M. (2003). Anxiety, fears, and phobias in persons with Williams syndrome. Developmental Neuropsychology, 23(1–2), 291–316. PubMed
Freeston, M. H., Rhéaume, J., Letarte, H., Dugas, M. J., & Ladouceur, R. (1994). Why do people worry? Personality and Individual Differences, 17(6), 791–802. https://doi.org/10.1016/0191-8869(94)90048-5.
Haas, B. W., Mills, D., Yam, A., Hoeft, F., Bellugi, U., & Reiss, A. (2009). Genetic influences on sociability: Heightened amygdala reactivity and event-related responses to positive social stimuli in Williams syndrome. Journal of Neuroscience, 29(4), 1132–1139. PubMed
Hillier, L. W., Fulton, R. S., Fulton, L. A., & Graves, T. A. (2003). The DNA sequence of human chromosome 7. Nature, 424(6945), 157–165. PubMed
Hocking, D. R. (2017). Williams syndrome. In N. J. Rinehart, J. L. Bradshaw & P. G. Enticott (Eds.), Developmental disorders of the brain (2nd ed., pp. 271–290). New York: Taylor Francis Group.
Hodgson, A. R., Freeston, M. H., Honey, E., & Rodgers, J. (2016). Facing the unknown: Intolerance of uncertainty in children with autism spectrum disorder. Journal of Applied Research in Intellectual Disabilities, 30(2), 336–344. PubMed
Ingersoll, B., Hopwood, C. J., Wainer, A., & Donnellan, M. B. (2011). A comparison of three self-report measures of the broader autism phenotype in a non-clinical sample. Journal of Autism and Developmental Disorders, 41(12), 1646–1657. PubMed
Isaac, L., & Lincoln, A. (2011). Featural versus configural face processing in a rare genetic disorder: Williams syndrome. Journal of Intellectual Disability Research, 55(11), 1034–1042. PubMed
Janes, E., Riby, D., & Rodgers, J. (2014). Exploring the prevalence and phenomenology of repetitive behaviours and abnormal sensory processing in children with Williams Syndrome. Journal of Intellectual Disability Research, 58(8), 746–757. PubMed
John, A. E., & Mervis, C. B. (2010). Sensory modulation impairments in children with Williams syndrome. American Journal of Medical Genetics. Part C: Seminars in Medical Genetics, 154(2), 266–276.
Kennedy, J. C., Kaye, D. L., & Sadler, L. S. (2006). Psychiatric diagnoses in patients with Williams syndrome and their families. Jefferson Journal of Psychiatry, 20(1), 22–31.
Kerns, C. M., Renno, P., Kendall, P. C., Wood, J. J., & Storch, E. A. (2017). Anxiety disorders interview schedule–autism Addendum: Reliability and validity in children with autism spectrum disorder. Journal of Clinical Child & Adolescent Psychology, 46(1), 88–100.
Kirk, H. E., Hocking, D. R., Riby, D. M., & Cornish, K. M. (2013). Linking social behaviour and anxiety to attention to emotional faces in Williams syndrome. Research in Developmental Disabilities, 34(12), 4608–4616. PubMed
Klein-Tasman, B. P., & Mervis, C. B. (2003). Distinctive personality characteristics of 8-, 9-, and 10-year-olds with Williams syndrome. Developmental Neuropsychology, 23(1–2), 269–290. PubMed
Klein-Tasman, B. P., Mervis, C. B., Lord, C., & Phillips, K. D. (2007). Socio-communicative deficits in young children with Williams syndrome: Performance on the autism diagnostic observation schedule. Child Neuropsychology, 13(5), 444–467. PubMed
Lee, J. K., Orsillo, S. M., Roemer, L., & Allen, L. B. (2010). Distress and avoidance in generalized anxiety disorder: Exploring the relationships with intolerance of uncertainty and worry. Cognitive Behaviour Threapy, 39, 126–136.
Leyfer, O., Woodruff-Borden, J., Klein-Tasman, B. P., Fricke, J. S., & Mervis, C. B. (2006). Prevalence of psychiatric disorders in 4 to 16-year-olds with Williams syndrome. American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics, 141(6), 615–622.
Lidstone, J., Uljarević, M., Sullivan, J., Rodgers, J., McConachie, H., Freeston, M., et al. (2014). Relations among restricted and repetitive behaviors, anxiety and sensory features in children with autism spectrum disorders. Research in Autism Spectrum Disorders, 8(2), 82–92.
Lincoln, A. J., Searcy, Y. M., Jones, W., & Lord, C. (2007). Social interaction behaviors discriminate young children with autism and Williams syndrome. Journal of the American Academy of Child and Adolescent Psychiatry, 46(3), 323–331. PubMed
Maisel, M. E., Stephenson, K. G., South, M., Rodgers, J., Freeston, M. H., & Gaigg, S. B. (2016). Modeling the cognitive mechanisms linking autism symptoms and anxiety in adults. Journal of Abnormal Psychology, 125(5), 692–703. PubMed
McEvoy, P. M., & Mahoney, A. E. (2011). Achieving certainty about the structure of intolerance of uncertainty in a treatment-seeking sample with anxiety and depression. Journal of Anxiety Disorders, 25(1), 112–122. PubMed
Mervis, C. B., & Klein-Tasman, B. P. (2000). Williams syndrome: Cognition, personality, and adaptive behavior. Mental Retardation and Developmental Disabilities Research Reviews, 6(2), 148–158. PubMed
Meyer-Lindenberg, A., Hariri, A. R., Munoz, K. E., Mervis, C. B., Mattay, V. S., Morris, C. A., et al. (2005). Neural correlates of genetically abnormal social cognition in Williams syndrome. Nature Neuroscience, 8(8), 991–993. PubMed
Möller, E. L., Majdandžić, M., Craske, M. G., & Bögels, S. M. (2014). Dimensional assessment of anxiety disorders in parents and children for DSM-5. International Journal of Methods in Psychiatric Research, 23(3), 331–344. PubMed
Porter, M. A., Shaw, T. A., & Marsh, P. J. (2010). An unusual attraction to the eyes in Williams-Beuren syndrome: A manipulation of facial affect while measuring face scanpaths. Cognitive Neuropsychiatry, 15(6), 505–530. PubMed
Riby, D. M., & Hancock, P. J. (2009). Do faces capture the attention of individuals with Williams syndrome or autism? Evidence from tracking eye movements. Journal of Autism and Developmental Disorders, 39(3), 421–431. PubMed
Riby, D. M., Hanley, M., Kirk, H., Clark, F., Little, K., Fleck, R., et al. (2014). The interplay between anxiety and social functioning in Williams syndrome. Journal of Autism and Developmental Disorders, 44(5), 1220–1229. PubMed
Riby, D. M., Janes, E., & Rodgers, J. (2013). Brief report: Exploring the relationship between sensory processing and repetitive behaviours in williams syndrome. Journal of Autism and Developmental Disorders, 43(2), 478–482. PubMed
Rodgers, J., Riby, D. M., Janes, E., Connolly, B., & McConachie, H. (2012). Anxiety and repetitive behaviours in autism spectrum disorders and Williams syndrome: A cross-syndrome comparison. Journal of Autism and Developmental Disorders, 42(2), 175–180. PubMed
Rodgers, J., Wigham, S., McConachie, H., Freeston, M., Honey, E., & Parr, J. R. (2016). Development of the anxiety scale for children with autism spectrum disorder (ASC-ASD). Autism Research, 9, 1205–1215. PubMed
Searcy, Y. M., Lincoln, A. J., Rose, F. E., Klima, E. S., Bavar, N., & Korenberg, J. R. (2004). The relationship between age and IQ in adults with Williams syndrome. American Journal of Mental Retardation, 109(3), 231–236. PubMed
Stinton, C., Tomlinson, K., & Estes, Z. (2012). Examining reports of mental health in adults with Williams syndrome. Research in Developmental Disabilities, 33(1), 144–152. PubMed
Sukhodolsky, D. G., Scahill, L., Gadow, K. D., Arnold, L. E., Aman, M. G., McDougle, C. J., et al. (2008). Parent-rated anxiety symptoms in children with pervasive developmental disorders: Frequency and association with core autism symptoms and cognitive functioning. [journal article]. Journal of Abnormal Child Psychology, 36(1), 117–128. https://doi.org/10.1007/s10802-007-9165-9. PubMed
Tantam, D. (2000). Psychological disorder in adolescents and adults with Asperger syndrome. Autism, 4(1), 47–62.
Udwin, O., Yule, W., & Martin, N. (1987). Cognitive abilities and behavioural characteristics of children with idiopathic infantile hypercalcaemia. Journal of Child Psychology and Psychiatry and Allied Disciplines, 28(2), 297–309.
Uljarević, M., Baranek, G., Vivanti, G., Hedley, D., Hudry, K., & Lane, A. (2017). Heterogeneity of sensory features in autism spectrum disorder: Challenges and perspectives for future research. Autism Research, 10(5), 703–710. PubMed
Uljarević, M., Carrington, S., & Leekam, S. (2016a). Brief report: Effects of sensory sensitivity and intolerance of uncertainty on anxiety in mothers of children with autism spectrum disorder. Journal of Autism and Developmental Disorders, 46(1), 315–319. PubMed
Uljarević, M., Nuske, H., & Vivanti, G. (2016b). Anxiety in autism spectrum disorder. In L. Mazzone & B. Vitiello (Eds.), Psychiatry comorbidity in autism spectrum disorders (pp. 21–38). Switzerland: Springer International Publishing.
van Steensel, F. J., Bögels, S. M., & Wood, J. J. (2013). Autism spectrum traits in children with anxiety disorders. Journal of Autism and Developmental Disorders, 43(2), 361–370. PubMed
Wigham, S., Rodgers, J., South, M., McConachie, H., & Freeston, M. (2015). The interplay between sensory processing abnormalities, intolerance of uncertainty, anxiety and restricted and repetitive behaviours in autism spectrum disorder. Journal of Autism and Developmental Disorders, 45(4), 943–952. PubMed
Wing, L. (1992). Manifestations of social problems in high-functioning autistic people. In E. Schopler & G. B. Mesibov (Eds.), High-functioning individuals with autism (pp. 129–142). New York: Springer.
Woodruff-Borden, J., Kistler, D. J., Henderson, D. R., Crawford, N. A., & Mervis, C. B. (2010). Longitudinal course of anxiety in children and adolescents with Williams syndrome. American Journal of Medical Genetics. Part C: Seminars in Medical Genetics, 154(2), 277–290.
- Brief Report: The Impact of Sensory Hypersensitivity and Intolerance of Uncertainty on Anxiety in Williams Syndrome
Darren R. Hocking
- Springer US