Top

Journal of Autism and Developmental Disorders

Gepubliceerd in:

11-01-2016 | Original Paper

Assessment of Cognitive Outcome Measures in Teenagers with 15q13.3 Microdeletion Syndrome

Auteurs: Emeline Crutcher, May Ali, John Harrison, Judit Sovago, Baltazar Gomez-Mancilla, Christian P. Schaaf

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 4/2016

Abstract

15q13.3 microdeletion syndrome causes a spectrum of cognitive disorders, including intellectual disability and autism. We aimed to determine if any or all of three cognitive testing systems (the KiTAP, CogState, and Stanford–Binet) are suitable for assessment of cognitive function in affected individuals. These three tests were administered to ten individuals with 15q13.3 microdeletion syndrome (14–18 years of age), and the results were analyzed to determine feasibility of use, potential for improvement, and internal consistency. It was determined that the KiTAP, CogState, and Stanford–Binet are valid tests of cognitive function in 15q13.3 microdeletion patients. Therefore, these tests may be considered for use as objective outcome measures in future clinical trials, assessing change in cognitive function over a period of pharmacological treatment.

vorige artikel Emergency Department Use Among Adults with Autism Spectrum Disorders (ASD)

volgende artikel Brief Report: Scurvy as a Manifestation of Food Selectivity in Children with Autism

Aman, M. G., Novotny, S., Samango-Sprouse, C., Lecavalier, L., Leonard, E., Gadow, K. D., et al. (2004). Outcome measures for clinical drug trials in autism. CNS Spectrums, 9(1), 36–47.PubMedPubMedCentral

Freedman, R. (2014). α7-nicotinic acetylcholine receptor agonists for cognitive enhancement in schizophrenia. Annual Review of Medicine, 65(September 2013), 245–261.CrossRefPubMed

Gillentine, M. A., & Schaaf, C. P. (2015). The human clinical phenotypes of altered CHRNA7 copy number. Biochemical Pharmacology. doi:10.1016/j.bcp.2015.06.012.PubMed

Grondhuis, S., & Mulick, J. (2013). Comparison of the Leiter International Performance Scale-Revised and the Stanford–Binet Intelligence Scales, 5th Edition, in children with autism spectrum disorders. American Journal on Intellectual and Developmental Disabilities, 118(1), 44–54.CrossRefPubMed

Hellwig-Brida, S., Daseking, M., Keller, F., Petermann, F., & Goldbeck, L. (2011). Effects of methylphenidate on intelligence and attention components in boys with attention-deficit/hyperactivity disorder. Journal of Child and Adolescent Psychopharmacology, 21(3), 245–253.CrossRefPubMed

Jucaite, A., Öhd, J., Potter, A. S., Jaeger, J., Karlsson, P., Hannesdottir, K., et al. (2014). A randomized, double-blind, placebo-controlled crossover study of α4β2* nicotinic acetylcholine receptor agonist AZD1446 (TC-6683) in adults with attention-deficit/hyperactivity disorder. Psychopharmacology, 231(6), 1251–1265.CrossRefPubMedPubMedCentral

Kaufmann, L., Zieren, N., Zotter, S., Karall, D., Scholl-Bürgi, S., Haberlandt, E., et al. (2010). Predictive validity of attentional functions in differentiating children with and without ADHD: A componential analysis. Developmental Medicine and Child Neurology, 52(4), 371–378.CrossRefPubMed

Knox, A., Schneider, A., Abucayan, F., Hervey, C., Tran, C., Hessl, D., et al. (2012). Feasibility, reliability, and clinical validity of the Test of Attentional Performance for Children (KiTAP) in Fragile X syndrome (FXS). Journal of Neurodevelopmental Disorders, 4(1), 2. doi:10.1186/1866-1955-4-2.CrossRefPubMedPubMedCentral

Lowther, C., Costain, G., Stavropoulos, D. J., Melvin, R., Silversides, C. K., Andrade, D. M., et al. (2014). Delineating the 15q13.3 microdeletion phenotype: A case series and comprehensive review of the literature. Genetics in Medicine, 17(2), 149–157.CrossRefPubMedPubMedCentral

MedFriendly: Standard Score to Percentile Conversion. (n.d.). Retrieved from http://www.medfriendly.com/standardscoretopercentileconversion.html. Accessed 2 June 2015.

Mollica, C. M., Maruff, P., & Vance, A. (2004). Development of a statistical approach to classifying treatment response in individual children with ADHD. Human Psychopharmacology, 19(7), 445–456.CrossRefPubMed

Ozonoff, S., Goodlin-Jones, B. L., & Solomon, M. (2005). Evidence-based assessment of autism spectrum disorders in children and adolescents. Journal of Clinical Child and Adolescent Psychology, 34(3), 523–540.CrossRefPubMed

Rothmann, K., Hillmer, J., & Hosser, D. (2014). Evaluation of the Musical Concentration Training with Pepe (MusiKo mit Pepe) for children with attention deficits. Zeitschrift für Kinder-und Jugendpsychiatrie und Psychotherapie, 42(5), 325–335.CrossRefPubMed

Sandler, A. (2005). Placebo effects in developmental disabilities: Implications for research and practice. Mental Retardation and Developmental Disabilities Research Reviews, 11(2), 164–170.CrossRefPubMed

Schaaf, C. P. (2014). Nicotinic acetylcholine receptors in human genetic disease. Genetics in Medicine, 16(9), 649–656.CrossRefPubMed

Silverman, W., Miezejeski, C., Ryan, R., Zigman, W., Krinsky-McHale, S., & Urv, T. (2010). Stanford–Binet and WAIS IQ differences and their implications for adults with intellectual disability (aka mental retardation). Intelligence, 38(2), 242–248.CrossRefPubMedPubMedCentral

Tropeano, M., Andrieux, J., Vassos, E., & Collier, D. A. (2014). Clinical utility gene card for: 15q13.3 microdeletion syndrome. European Journal of Human Genetics, 22(11), 1338.CrossRefPubMedCentral

Yamashita, Y., Mukasa, A., Anai, C., Honda, Y., Kunisaki, C., Koutaki, J., et al. (2011). Summer treatment program for children with attention deficit hyperactivity disorder: Japanese experience in 5 years. Brain and Development, 33(3), 260–267.CrossRefPubMed

Titel: Assessment of Cognitive Outcome Measures in Teenagers with 15q13.3 Microdeletion Syndrome
Auteurs: Emeline Crutcher
May Ali
John Harrison
Judit Sovago
Baltazar Gomez-Mancilla
Christian P. Schaaf
Publicatiedatum: 11-01-2016
Uitgeverij: Springer US
Gepubliceerd in: Journal of Autism and Developmental Disorders / Uitgave 4/2016
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI: https://doi.org/10.1007/s10803-015-2694-0

Bohn Stafleu van Loghum

Deel dit onderdeel of sectie (kopieer de link)

Abstract

Log in om toegang te krijgen

Andere artikelen Uitgave 4/2016

Distinctive Role of Symbolic Number Sense in Mediating the Mathematical Abilities of Children with Autism

Inclusion of Children with Autism Spectrum Disorders: Listening and Hearing to Voices from the Grassroots

Restricted and Repetitive Behaviors as Predictors of Outcome in Autism Spectrum Disorders

Autism Spectrum Disorder in Children Adopted After Early Care Breakdown

Perceived Friendship Quality of Children with Autism Spectrum Disorder as Compared to their Peers in Mixed and Non-mixed Dyads

The Experience of Social Participation in Everyday Contexts Among Individuals with Autism Spectrum Disorders: An Experience Sampling Study