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Journal of Autism and Developmental Disorders

Gepubliceerd in:

01-04-2015 | Original Paper

Successful Face Recognition is Associated with Increased Prefrontal Cortex Activation in Autism Spectrum Disorder

Auteurs: John D. Herrington, Meghan E. Riley, Daniel W. Grupe, Robert T. Schultz

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 4/2015

Abstract

This study examines whether deficits in visual information processing in autism-spectrum disorder (ASD) can be offset by the recruitment of brain structures involved in selective attention. During functional MRI, 12 children with ASD and 19 control participants completed a selective attention one-back task in which images of faces and houses were superimposed. When attending to faces, the ASD group showed increased activation relative to control participants within multiple prefrontal cortex areas, including dorsolateral prefrontal cortex (DLPFC). DLPFC activation in ASD was associated with increased response times for faces. These data suggest that prefrontal cortex activation may represent a compensatory mechanism for diminished visual information processing abilities in ASD.

vorige artikel New Interview and Observation Measures of the Broader Autism Phenotype: Group Differentiation

volgende artikel Varieties of Misdiagnosis in ASD: An Illustrative Case Series

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Titel: Successful Face Recognition is Associated with Increased Prefrontal Cortex Activation in Autism Spectrum Disorder
Auteurs: John D. Herrington
Meghan E. Riley
Daniel W. Grupe
Robert T. Schultz
Publicatiedatum: 01-04-2015
Uitgeverij: Springer US
Gepubliceerd in: Journal of Autism and Developmental Disorders / Uitgave 4/2015
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI: https://doi.org/10.1007/s10803-014-2233-4

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