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03-02-2017 | Original Paper

Quantitative Sensory Testing in adults with Autism Spectrum Disorders

Auteurs: Odette Fründt, Wiebke Grashorn, Daniel Schöttle, Ina Peiker, Nicole David, Andreas K. Engel, Katarina Forkmann, Nathalie Wrobel, Alexander Münchau, Ulrike Bingel

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 4/2017

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Abstract

Altered sensory perception has been found in patients with autism spectrum disorders (ASD) and might be related to aberrant sensory perception thresholds. We used the well-established, standardized Quantitative sensory testing (QST) protocol of the German Research Network on Neuropathic Pain to investigate 13 somatosensory parameters including thermal and tactile detection and pain thresholds in 13 ASD adults and 13 matched healthy controls with normal IQ values. There were no group differences between somatosensory detection and pain thresholds. Two ASD patients showed paradoxical heat sensations and another two ASD subjects presented dynamic mechanical allodynia; somatosensory features that were absent in controls. These findings suggest that central mechanisms during complex stimulus integration rather than peripheral dysfunctions probably determine somatosensory alterations in ASD.
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Metagegevens
Titel
Quantitative Sensory Testing in adults with Autism Spectrum Disorders
Auteurs
Odette Fründt
Wiebke Grashorn
Daniel Schöttle
Ina Peiker
Nicole David
Andreas K. Engel
Katarina Forkmann
Nathalie Wrobel
Alexander Münchau
Ulrike Bingel
Publicatiedatum
03-02-2017
Uitgeverij
Springer US
Gepubliceerd in
Journal of Autism and Developmental Disorders / Uitgave 4/2017
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI
https://doi.org/10.1007/s10803-017-3041-4