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26-11-2021 | ORIGINAL PAPER

Mindful Non-judging and Experiential Avoidance Before Allogeneic Hematopoietic Stem Cell Transplantation (HSCT) are Associated to Post-traumatic Stress Disorder (PTSD) Symptomatology 5 Months Later

Auteurs: Maya Corman, Marie-Thérèse Rubio, Aurélie Cabrespine, Isabelle Brindel, Jacques-Olivier Bay, Régis Peffault De La Tour, Michaël Dambrun

Gepubliceerd in: Mindfulness | Uitgave 1/2022

Abstract

Objectives

Hematopoietic stem cell transplantation (HSCT) can be a traumatic experience for the patient, engendering psychological distress and sometimes post-traumatic stress disorder (PTSD). The aim of this study was to explore the relations between psychological resources (i.e., dispositional mindfulness, optimism, and acceptance) and deleterious factors (i.e., experiential avoidance and alexithymia) assessed before HSCT on PTSD symptomatology 5 months after transplantation. The relations between symptoms of PTSD and the five facets of dispositional mindfulness were also explored.

Methods

Among the 187 patients who completed the first questionnaire measuring dispositional factors (i.e., dispositional mindfulness, acceptance, optimism, experiential avoidance, and alexithymia) prior to hospitalization, 91 patients were assessed at 5 months after HSCT on PTSD symptomatology. Various medical and mental health variables were controlled.

Results

Acceptance, experiential avoidance, and the non-judging facet of mindfulness correlated significantly with PTSD symptoms at 5 months. Adjusting for major comorbid psychiatric disorders of PTSD (i.e., anxiety and depression), only experiential avoidance and mindful non-judging remained significant correlates of PTSD symptomatology. In addition, controlling for the same comorbidities, a binary logistic regression analysis revealed that only the non-judging facet of mindfulness is related to a lower risk of developing symptoms of PTSD (OR = 0.38, p < .01; 95% CI: 0.16, 0.95).

Conclusions

This study highlights the importance of psychological constructs barely explored in HSCT. Cultivating a state of non-judgment and non-avoidance of internal experiences is negatively associated to PTSD symptoms following HSCT.

Trial registration

NCT03883672 (March 21, 2019).

vorige artikel A Qualitative Study of the LGBTQ+ Youth Affirmative Mindfulness Program for Sexual and Gender Minority Youth

volgende artikel Effects of a Mindful Parenting Workshop for Parents of Adolescents and Young Adults Following Social Unrest in Hong Kong

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Titel: Mindful Non-judging and Experiential Avoidance Before Allogeneic Hematopoietic Stem Cell Transplantation (HSCT) are Associated to Post-traumatic Stress Disorder (PTSD) Symptomatology 5 Months Later
Auteurs: Maya Corman
Marie-Thérèse Rubio
Aurélie Cabrespine
Isabelle Brindel
Jacques-Olivier Bay
Régis Peffault De La Tour
Michaël Dambrun
Publicatiedatum: 26-11-2021
Uitgeverij: Springer US
Gepubliceerd in: Mindfulness / Uitgave 1/2022
Print ISSN: 1868-8527
Elektronisch ISSN: 1868-8535
DOI: https://doi.org/10.1007/s12671-021-01788-1

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Abstract

Objectives

Methods

Results

Conclusions

Trial registration

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