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A Randomized Study of the Effects of Mindfulness Training on Psychological Well-being and Symptoms of Stress in Patients Treated for Cancer at 6-month Follow-up

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Abstract

Background

There is increasing evidence showing beneficial effects of mindfulness and mindfulness training on various indicators of mental and physical health.

Purpose

This paper reports the 6-month follow-up effects of a mindfulness stress reduction training program among patients treated for cancer on perceived stress, depression, anxiety, post-traumatic stress symptoms, positive states of mind, coping self-efficacy, and mindfulness.

Methods

Patients with a previous cancer diagnosis were recruited and randomized into an intervention group or a waiting list control group. The intervention consisted of an 8-week mindfulness training course.

Results

Compared to participants in the control group, the intervention group showed a larger increase in mindfulness at 6-month follow-up. However, there were no differences on any of the other outcomes between the intervention and control groups. Continued meditation practice was associated with a significant reduction in post-traumatic stress symptoms of avoidance.

Conclusions

The study draws attention to the need to better understand the mechanisms behind the effect of mindfulness training and to potential modification of mindfulness interventions to promote sustained benefits over time.

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References

  1. McGregor BA, Antoni MH. Psychological intervention and health outcomes among women treated for breast cancer: a review of stress pathways and biological mediators. Brain Behav Immun. 2009;23(2):159–66.

    Article  PubMed  CAS  Google Scholar 

  2. Hoffman KE et al. Psychological distress in long-term survivors of adult-onset cancer: results from a national survey. Arch Intern Med. 2009;169(14):1274–81.

    Article  PubMed  Google Scholar 

  3. Kabat-Zinn J. Full catastrophe living: using the wisdom of your body and mind to face stress, pain and illness. New York: Delacourt; 1990.

    Google Scholar 

  4. Bishop SR. What do we really know about mindfulness-based stress reduction? Psychosom Med. 2002;64(1):71–83.

    PubMed  Google Scholar 

  5. Carlson LE, Garland SN. Impact of mindfulness-based stress reduction (MBSR) on sleep, mood, stress and fatigue symptoms in cancer outpatients. Int J Behav Med. 2005;12(4):278–85.

    Article  PubMed  Google Scholar 

  6. Carlson LE et al. Mindfulness-based stress reduction in relation to quality of life, mood, symptoms of stress, and immune parameters in breast and prostate cancer outpatients. Psychosom Med. 2003;65(4):571–81.

    Article  PubMed  Google Scholar 

  7. Grossman P et al. Mindfulness-based stress reduction and health benefits. A meta-analysis. J Psychosom Res. 2004;57(1):35–43.

    Article  PubMed  Google Scholar 

  8. Smith JE et al. Mindfulness-based stress reduction as supportive therapy in cancer care: systematic review. J Adv Nurs. 2005;52(3):315–27.

    Article  PubMed  Google Scholar 

  9. Carlson LE et al. The effects of a mindfulness meditation-based stress reduction program on mood and symptoms of stress in cancer outpatients: 6-month follow-up. Support Care Cancer. 2001;9(2):112–23.

    Article  PubMed  CAS  Google Scholar 

  10. Speca M et al. A randomized, wait-list controlled clinical trial: the effect of a mindfulness meditation-based stress reduction program on mood and symptoms of stress in cancer outpatients. Psychosom Med. 2000;62(5):613–22.

    PubMed  CAS  Google Scholar 

  11. Lengacher CA, et al. (2009) Randomized controlled trial of mindfulness-based stress reduction (MBSR) for survivors of breast cancer. Psychooncology

  12. Shapiro SL et al. The efficacy of mindfulness-based stress reduction in the treatment of sleep disturbance in women with breast cancer: an exploratory study. J Psychosom Res. 2003;54(1):85–91.

    Article  PubMed  Google Scholar 

  13. Ledesma D, Kumano H. Mindfulness-based stress reduction and cancer: a meta-analysis. Psychooncology. 2009;18(6):571–9.

    Article  PubMed  Google Scholar 

  14. Carlson LE et al. One year pre-post intervention follow-up of psychological, immune, endocrine and blood pressure outcomes of mindfulness-based stress reduction (MBSR) in breast and prostate cancer outpatients. Brain Behav Immun. 2007;21(8):1038–49.

    Article  PubMed  CAS  Google Scholar 

  15. Bränström R et al. Self-report mindfulness as a mediator of psychological well-being in a stress reduction intervention for cancer patients—a randomized study. Ann Behav Med. 2010;39(2):151–61.

    Article  PubMed  Google Scholar 

  16. SPSS Inc. SPSS 15.0 for Windows. Chicago: SPSS Inc.; 1999.

    Google Scholar 

  17. Cohen S, Kamarck T, Mermelstein R. A global measure of perceived stress. J Health Soc Behav. 1983;24(4):385–96.

    Article  PubMed  CAS  Google Scholar 

  18. Bjelland I et al. The validity of the Hospital Anxiety and Depression Scale. An updated literature review. J Psychosom Res. 2002;52(2):69–77.

    Article  PubMed  Google Scholar 

  19. Weiss D, Marmar C. The Impact of Event Scale—Revised. In: Wilson J, Keane T, editors. Assessing psychological trauma and PTSD. New York: Guilford; 1996. p. 399–411.

    Google Scholar 

  20. Horowitz M, Wilner N, Alvarex W. Impact of Event Scale: a measure of subjective stress. Psychosom Med. 1979;41(3):209–18.

    PubMed  CAS  Google Scholar 

  21. Adler NE et al. Additional validation of a scale to assess positive states of mind. Psychosom Med. 1998;60(1):26–32.

    PubMed  CAS  Google Scholar 

  22. Horowitz M, Adler N, Kegeles S. A scale for measuring the occurrence of positive states of mind: a preliminary report. Psychosom Med. 1988;50(5):477–83.

    PubMed  CAS  Google Scholar 

  23. Chesney MA et al. A validity and reliability study of the coping self-efficacy scale. Br J Health Psychol. 2006;11(3):421–37.

    Article  PubMed  Google Scholar 

  24. Baer RA et al. Using self-report assessment methods to explore facets of mindfulness. Assessment. 2006;13(1):27–45.

    Article  PubMed  Google Scholar 

  25. Baer RA et al. Construct validity of the five facet mindfulness questionnaire in meditating and nonmeditating samples. Assessment. 2008;15(3):329–42.

    Article  PubMed  Google Scholar 

  26. Bränström R, Duncan L, Moskowitz JT. The association between dispositional mindfulness, psychological well-being and perceived health in a Swedish population-based sample. Br J Heal Psychol. 2010;16:300–16.

    Article  Google Scholar 

  27. Carlson LE et al. Mindfulness-based stress reduction in relation to quality of life, mood, symptoms of stress and levels of cortisol, dehydroepiandrosterone sulfate (DHEAS) and melatonin in breast and prostate cancer outpatients. Psychoneuroendocrinology. 2004;29(4):448–74.

    Article  PubMed  CAS  Google Scholar 

  28. Witek-Janusek L et al. Effect of mindfulness based stress reduction on immune function, quality of life and coping in women newly diagnosed with early stage breast cancer. Brain Behav Immun. 2008;22(6):969–81.

    Article  PubMed  Google Scholar 

  29. Carmody J, Baer RA. Relationships between mindfulness practice and levels of mindfulness, medical and psychological symptoms and well-being in a mindfulness-based stress reduction program. J Behav Med. 2008;31(1):23–33.

    Article  PubMed  Google Scholar 

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Acknowledgments

This research was funded by a research grant from the Osher Center for Integrative Medicine at the Karolinska Institute, Sweden. Richard Bränström is funded by research grants from the Swedish Council for Working Life and Social Research (Nr: 2006–1264 and 2006–0069), Center for Health Care Science at the Karolinska Institute, Sweden (Nr: 2008–4737), the Swedish Cancer Society, and Cancer-och Trafikskadades Riksförbund, Sweden.

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Correspondence to Richard Bränström.

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Bränström, R., Kvillemo, P. & Moskowitz, J.T. A Randomized Study of the Effects of Mindfulness Training on Psychological Well-being and Symptoms of Stress in Patients Treated for Cancer at 6-month Follow-up. Int.J. Behav. Med. 19, 535–542 (2012). https://doi.org/10.1007/s12529-011-9192-3

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  • DOI: https://doi.org/10.1007/s12529-011-9192-3

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