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29-05-2020 | Original Paper

Grey-Matter Thickness of the Left But Not the Right Primary Visual Area Correlates with Autism Traits in Typically Developing Adults

Auteurs: Gizem Y. Yildiz, Julian S. Vilsten, Amy Siobhan Millard, Philippe A. Chouinard

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 2/2021

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Abstract

We examined whether functional and structural variability in the primary visual area (V1) correlated with autism traits. Twenty-nine participants (16 males; MAge = 26.4 years, SDAge = 4.0 years) completed the autism-spectrum quotient (AQ) questionnaire prior to a magnetic resonance imaging session. The total AQ scores was used to assess the degree of self-reported autism traits. The average functional activation in V1 to visual stimulation and its average grey-matter thickness were calculated. There were no correlations between functional activation in V1 and autism traits. Conversely, grey-matter thickness of the left but not the right V1 correlated with autism traits. We conclude that structural changes in the left V1 could be a marker for the presence of autism traits.
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Literatuur
go back to reference American Psychiatric Association. (2013). DSM-V: Diagnostic and statistical manual of mental disorders, 5th edition. Washington: DC: American Psychiatric Publishing, Inc. American Psychiatric Association. (2013). DSM-V: Diagnostic and statistical manual of mental disorders, 5th edition. Washington: DC: American Psychiatric Publishing, Inc.
go back to reference Baron-Cohen, S., Wheelwright, S., Skinner, R., Martin, J., & Clubley, E. (2001). The autism-spectrum quotient (AQ): Evidence from Asperger syndrome/high-functioning autism, males and females, scientists and mathematicians. Journal of Autism and Developmental Disorders, 31(1), 5–17. https://doi.org/10.1023/a:1005653411471.CrossRef Baron-Cohen, S., Wheelwright, S., Skinner, R., Martin, J., & Clubley, E. (2001). The autism-spectrum quotient (AQ): Evidence from Asperger syndrome/high-functioning autism, males and females, scientists and mathematicians. Journal of Autism and Developmental Disorders, 31(1), 5–17. https://​doi.​org/​10.​1023/​a:​1005653411471.CrossRef
go back to reference Brainard, D. H. (2011). The psychophysics toolbox. Spatial Vision, 10, 433–436.CrossRef Brainard, D. H. (2011). The psychophysics toolbox. Spatial Vision, 10, 433–436.CrossRef
go back to reference Hyde, K. L., Samson, F., Evans, A. C., & Mottron, L. (2010). Neuroanatomical differences in brain areas implicated in perceptual and other core features of autism revealed by cortical thickness analysis and voxel-based morphometry. Human Brain Mapping, 31(4), 556–566. https://doi.org/10.1002/hbm.20887.CrossRefPubMed Hyde, K. L., Samson, F., Evans, A. C., & Mottron, L. (2010). Neuroanatomical differences in brain areas implicated in perceptual and other core features of autism revealed by cortical thickness analysis and voxel-based morphometry. Human Brain Mapping, 31(4), 556–566. https://​doi.​org/​10.​1002/​hbm.​20887.CrossRefPubMed
go back to reference Jeffreys, H. (1961). Theory of probability (3rd ed.). Oxford: Oxford University Press. Jeffreys, H. (1961). Theory of probability (3rd ed.). Oxford: Oxford University Press.
go back to reference Lainhart, J. E., & Lange, N. (2011). The biological broader autism phenotype. In G. D. D. G. Amaral & D. H. Geschwind (Eds.), Autism spectrum disorders. New York: Oxford University Press, Inc. Lainhart, J. E., & Lange, N. (2011). The biological broader autism phenotype. In G. D. D. G. Amaral & D. H. Geschwind (Eds.), Autism spectrum disorders. New York: Oxford University Press, Inc.
go back to reference Pelli, D. G. (1997). The VideoToolbox software for visual psychophysics: Transforming numbers into movies. Spatial Vision, 10, 437–442.CrossRef Pelli, D. G. (1997). The VideoToolbox software for visual psychophysics: Transforming numbers into movies. Spatial Vision, 10, 437–442.CrossRef
go back to reference Sawyer-Glover, A. M., & Shellock, F. G. (2000). Pre-MRI procedure screening: Recommendations and safety considerations for biomedical implants and devices. Journal of Magnetic Resonance Imaging, 12(1), 92–106.CrossRef Sawyer-Glover, A. M., & Shellock, F. G. (2000). Pre-MRI procedure screening: Recommendations and safety considerations for biomedical implants and devices. Journal of Magnetic Resonance Imaging, 12(1), 92–106.CrossRef
Metagegevens
Titel
Grey-Matter Thickness of the Left But Not the Right Primary Visual Area Correlates with Autism Traits in Typically Developing Adults
Auteurs
Gizem Y. Yildiz
Julian S. Vilsten
Amy Siobhan Millard
Philippe A. Chouinard
Publicatiedatum
29-05-2020
Uitgeverij
Springer US
Gepubliceerd in
Journal of Autism and Developmental Disorders / Uitgave 2/2021
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI
https://doi.org/10.1007/s10803-020-04553-w

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