Skip to main content
Top
Gepubliceerd in:

09-06-2022

Drift-Diffusion Model Reveals Impaired Reward-Based Perceptual Decision-Making Processes Associated with Depression in Late Childhood and Early Adolescent Girls

Auteurs: Riddhi J. Pitliya, Brady D. Nelson, Ph.D., Greg Hajcak, Ph.D., Jingwen Jin, Ph.D.

Gepubliceerd in: Research on Child and Adolescent Psychopathology | Uitgave 11/2022

Log in om toegang te krijgen
share
DELEN

Deel dit onderdeel of sectie (kopieer de link)

  • Optie A:
    Klik op de rechtermuisknop op de link en selecteer de optie “linkadres kopiëren”
  • Optie B:
    Deel de link per e-mail

Abstract

Adolescent girls are a high-risk stratum for the emergence of depression. Previous research has established that depression is associated with blunted responses to rewards. Research using Drift Diffusion Model (DDM) has found that deficits in accumulating reward-based evidence characterize adult depression. However, little is known about how reduced reward sensitivity is reflected in the computational processes involved in reward-based decision-making in late childhood and early adolescent depression.
One hundred and sixty-six 8- to 14-year-old girls completed a probabilistic reward-based decision-making task. Participants were instructed to identify which one of two similar visual stimuli were presented, and correct responses were rewarded with unequal probabilities. Analysis using hierarchical DDM quantified rate of evidence accumulation (i.e., drift rate) and starting point. Depression severity was measured using the Children’s Depression Inventory.
Across all participants, there was a higher drift rate, indicating faster evidence accumulation, for the more frequently rewarded than the less frequently rewarded decision. In addition, the starting point of the evidence accumulation was closer to the more frequently rewarded decision, indicating a starting point bias. Higher depression severity was associated with a slower drift rate for both types of decisions. Higher depression severity was associated with a smaller starting point bias towards the more frequently rewarded decision.
The current study uses computational modeling to reveal that late childhood and early adolescent girls with greater depression demonstrate impairments in the reward-related evidence accumulation process.
Bijlagen
Alleen toegankelijk voor geautoriseerde gebruikers
Voetnoten
1
We also investigated clinician-rated depression diagnosis using K-SADS as an alternative approach toward conceptualizing and quantifying depression, in which eight individuals formed the depressed group and the rest formed the non-depressed group. A between-group comparison supported the findings observed using the dimensional approach.
 
Literatuur
go back to reference Birmaher, B., Williamson, D. E., Dahl, R. E., Axelson, D. A., Kaufman, J., Dorn, L. D., & Ryan, N. D. (2004). Clinical Presentation and Course of Depression in Youth: Does Onset in Childhood Differ From Onset in Adolescence? Journal of the American Academy of Child & Adolescent Psychiatry, 43(1), 63–70. doi:https://doi.org/10.1097/00004583-200401000-00015CrossRef Birmaher, B., Williamson, D. E., Dahl, R. E., Axelson, D. A., Kaufman, J., Dorn, L. D., & Ryan, N. D. (2004). Clinical Presentation and Course of Depression in Youth: Does Onset in Childhood Differ From Onset in Adolescence? Journal of the American Academy of Child & Adolescent Psychiatry, 43(1), 63–70. doi:https://​doi.​org/​10.​1097/​00004583-200401000-00015CrossRef
go back to reference Bottemanne, L., & Dreher, J. C. (2019). Vicarious rewards modulate the drift rate of evidence accumulation from the drift diffusion model. Frontiers in Behavioral Neuroscience, 13, 142CrossRefPubMedPubMedCentral Bottemanne, L., & Dreher, J. C. (2019). Vicarious rewards modulate the drift rate of evidence accumulation from the drift diffusion model. Frontiers in Behavioral Neuroscience, 13, 142CrossRefPubMedPubMedCentral
go back to reference Bress, J. N., Smith, E., Foti, D., Klein, D. N., & Hajcak, G. (2012). Neural response to reward and depressive symptoms in late childhood to early adolescence. Biological psychology, 89(1), 156–162CrossRefPubMed Bress, J. N., Smith, E., Foti, D., Klein, D. N., & Hajcak, G. (2012). Neural response to reward and depressive symptoms in late childhood to early adolescence. Biological psychology, 89(1), 156–162CrossRefPubMed
go back to reference Casey, B. (2015). Beyond simple models of self-control to circuit-based accounts of adolescent behavior. Annual Review of Psychology, 66, 295–319CrossRefPubMed Casey, B. (2015). Beyond simple models of self-control to circuit-based accounts of adolescent behavior. Annual Review of Psychology, 66, 295–319CrossRefPubMed
go back to reference Cavanagh, J. F., Wiecki, T. V., Cohen, M. X., Figueroa, C. M., Samanta, J., Sherman, S. J., & Frank, M. J. (2011). Subthalamic nucleus stimulation reverses mediofrontal influence over decision threshold. Nature neuroscience, 14(11), 1462–1467CrossRefPubMedPubMedCentral Cavanagh, J. F., Wiecki, T. V., Cohen, M. X., Figueroa, C. M., Samanta, J., Sherman, S. J., & Frank, M. J. (2011). Subthalamic nucleus stimulation reverses mediofrontal influence over decision threshold. Nature neuroscience, 14(11), 1462–1467CrossRefPubMedPubMedCentral
go back to reference Compas, B. E., Connor-Smith, J., & Jaser, S. S. (2004). Temperament, stress reactivity, and coping:implications for depression in childhood and adolescence. Journal Of Clinical Child And Adolescent Psychology : The Official Journal For The Society Of Clinical Child And Adolescent Psychology, American Psychological Association, Division 53, 33(1), 21–31. doi:https://doi.org/10.1207/S15374424JCCP3301_3CrossRefPubMed Compas, B. E., Connor-Smith, J., & Jaser, S. S. (2004). Temperament, stress reactivity, and coping:implications for depression in childhood and adolescence. Journal Of Clinical Child And Adolescent Psychology : The Official Journal For The Society Of Clinical Child And Adolescent Psychology, American Psychological Association, Division 53, 33(1), 21–31. doi:https://​doi.​org/​10.​1207/​S15374424JCCP330​1_​3CrossRefPubMed
go back to reference Forbes, E. E., et al. (2007). “Alterations in Reward-Related Decision Making in Boys with Recent and Future Depression. " Biological psychiatry, 61(5), 633–639CrossRefPubMed Forbes, E. E., et al. (2007). “Alterations in Reward-Related Decision Making in Boys with Recent and Future Depression. " Biological psychiatry, 61(5), 633–639CrossRefPubMed
go back to reference Gelman, A., & Rubin, D. B. (1992). Inference from iterative simulation using multiple sequences. Statistical science, 7(4), 457–472CrossRef Gelman, A., & Rubin, D. B. (1992). Inference from iterative simulation using multiple sequences. Statistical science, 7(4), 457–472CrossRef
go back to reference Gold, J. I., & Shadlen, M. N. (2007). The neural basis of decision making. Annual Review Of Neuroscience, 30, 535–574CrossRefPubMed Gold, J. I., & Shadlen, M. N. (2007). The neural basis of decision making. Annual Review Of Neuroscience, 30, 535–574CrossRefPubMed
go back to reference Green, D. M., & Swets, J. A. (1996). Signal detection theory and psychophysics (1 vol., pp. 1969–1912). New York: Wiley Green, D. M., & Swets, J. A. (1996). Signal detection theory and psychophysics (1 vol., pp. 1969–1912). New York: Wiley
go back to reference Kaufman, J., Birmaher, B., Brent, D., Rao, U., Flynn, C., Moreci, P., & Ryan, N. (1997). Schedule for affective disorders and schizophrenia for school-age children-present and lifetime version (K-SADS-PL): initial reliability and validity data. Journal of the American Academy of Child & Adolescent Psychiatry, 36(7), 980–988CrossRef Kaufman, J., Birmaher, B., Brent, D., Rao, U., Flynn, C., Moreci, P., & Ryan, N. (1997). Schedule for affective disorders and schizophrenia for school-age children-present and lifetime version (K-SADS-PL): initial reliability and validity data. Journal of the American Academy of Child & Adolescent Psychiatry, 36(7), 980–988CrossRef
go back to reference Khazanov, G. K., & Ruscio, A. M. (2016). Is low positive emotionality a specific risk factor for depression? A meta-analysis of longitudinal studies. Psychological Bulletin, 142(9), 991CrossRefPubMedPubMedCentral Khazanov, G. K., & Ruscio, A. M. (2016). Is low positive emotionality a specific risk factor for depression? A meta-analysis of longitudinal studies. Psychological Bulletin, 142(9), 991CrossRefPubMedPubMedCentral
go back to reference Kluyver, T., Ragan-Kelley, B., Pérez, F., Granger, B. E., Bussonnier, M., Frederic, J., & Corlay, S. (2016). Jupyter Notebooks-a publishing format for reproducible computational workflows. Paper presented at the ELPUB Kluyver, T., Ragan-Kelley, B., Pérez, F., Granger, B. E., Bussonnier, M., Frederic, J., & Corlay, S. (2016). Jupyter Notebooks-a publishing format for reproducible computational workflows. Paper presented at the ELPUB
go back to reference Kotov, R., Krueger, R. F., Watson, D., Achenbach, T. M., Althoff, R. R., Bagby, R. M., & Clark, L. A. (2017). The Hierarchical Taxonomy of Psychopathology (HiTOP): A dimensional alternative to traditional nosologies. Journal of Abnormal Psychology, 126(4), 454CrossRefPubMed Kotov, R., Krueger, R. F., Watson, D., Achenbach, T. M., Althoff, R. R., Bagby, R. M., & Clark, L. A. (2017). The Hierarchical Taxonomy of Psychopathology (HiTOP): A dimensional alternative to traditional nosologies. Journal of Abnormal Psychology, 126(4), 454CrossRefPubMed
go back to reference Kovacs, M. (1992). Children’s depression inventory: Manual. NY: Multi-Health Systems North Tonawanda Kovacs, M. (1992). Children’s depression inventory: Manual. NY: Multi-Health Systems North Tonawanda
go back to reference Lawlor, V. M., Webb, C. A., Wiecki, T. V., Frank, M. J., Trivedi, M., Pizzagalli, D. A., & Dillon, D. G. (2019). Dissecting the impact of depression on decision-making.Psychological medicine,1–10 Lawlor, V. M., Webb, C. A., Wiecki, T. V., Frank, M. J., Trivedi, M., Pizzagalli, D. A., & Dillon, D. G. (2019). Dissecting the impact of depression on decision-making.Psychological medicine,1–10
go back to reference Metcalfe, J., & Mischel, W. (1999). A hot/cool-system analysis of delay of gratification: dynamics of willpower. Psychological review, 106(1), 3CrossRefPubMed Metcalfe, J., & Mischel, W. (1999). A hot/cool-system analysis of delay of gratification: dynamics of willpower. Psychological review, 106(1), 3CrossRefPubMed
go back to reference Metin, B., Roeyers, H., Wiersema, J. R., van der Meere, J. J., Thompson, M., & Sonuga-Barke, E. (2013). ADHD performance reflects inefficient but not impulsive information processing: A diffusion model analysis. Neuropsychology, 27(2), 193CrossRefPubMed Metin, B., Roeyers, H., Wiersema, J. R., van der Meere, J. J., Thompson, M., & Sonuga-Barke, E. (2013). ADHD performance reflects inefficient but not impulsive information processing: A diffusion model analysis. Neuropsychology, 27(2), 193CrossRefPubMed
go back to reference Milosavljevic, M., Malmaud, J., Huth, A., Koch, C., & Rangel, A. (2010). The drift diffusion model can account for value-based choice response times under high and low time pressure. Judgment and Decision Making, 5(6), 437–449CrossRef Milosavljevic, M., Malmaud, J., Huth, A., Koch, C., & Rangel, A. (2010). The drift diffusion model can account for value-based choice response times under high and low time pressure. Judgment and Decision Making, 5(6), 437–449CrossRef
go back to reference Olino, T. M., Lopez-Duran, N. L., Kovacs, M., George, C. J., Gentzler, A. L., & Shaw, D. S. (2011). Developmental trajectories of positive and negative affect in children at high and low familial risk for depressive disorder. Journal of Child Psychology and Psychiatry, 52(7), 792–799CrossRefPubMed Olino, T. M., Lopez-Duran, N. L., Kovacs, M., George, C. J., Gentzler, A. L., & Shaw, D. S. (2011). Developmental trajectories of positive and negative affect in children at high and low familial risk for depressive disorder. Journal of Child Psychology and Psychiatry, 52(7), 792–799CrossRefPubMed
go back to reference Patton, G. C., Coffey, C., Romaniuk, H., Mackinnon, A., Carlin, J. B., Degenhardt, L., & Moran, P. (2014). The prognosis of common mental disorders in adolescents: a 14-year prospective cohort study. The Lancet, 383(9926), 1404–1411CrossRef Patton, G. C., Coffey, C., Romaniuk, H., Mackinnon, A., Carlin, J. B., Degenhardt, L., & Moran, P. (2014). The prognosis of common mental disorders in adolescents: a 14-year prospective cohort study. The Lancet, 383(9926), 1404–1411CrossRef
go back to reference Pizzagalli, D. A., Jahn, A. L., & O’Shea, J. P. (2005). Toward an objective characterization of an anhedonic phenotype: a signal-detection approach. Biological psychiatry, 57(4), 319–327CrossRefPubMedPubMedCentral Pizzagalli, D. A., Jahn, A. L., & O’Shea, J. P. (2005). Toward an objective characterization of an anhedonic phenotype: a signal-detection approach. Biological psychiatry, 57(4), 319–327CrossRefPubMedPubMedCentral
go back to reference Ratcliff, R. (1978). A theory of memory retrieval. Psychological review, 85(2), 59CrossRef Ratcliff, R. (1978). A theory of memory retrieval. Psychological review, 85(2), 59CrossRef
go back to reference Ratcliff, R., & Rouder, J. N. (1998). Modeling response times for two-choice decisions. Psychological science, 9(5), 347–356CrossRef Ratcliff, R., & Rouder, J. N. (1998). Modeling response times for two-choice decisions. Psychological science, 9(5), 347–356CrossRef
go back to reference Ratcliff, R., Smith, P. L., Brown, S. D., & McKoon, G. (2016). Diffusion decision model: Current issues and history. Trends in cognitive sciences, 20(4), 260–281CrossRefPubMedPubMedCentral Ratcliff, R., Smith, P. L., Brown, S. D., & McKoon, G. (2016). Diffusion decision model: Current issues and history. Trends in cognitive sciences, 20(4), 260–281CrossRefPubMedPubMedCentral
go back to reference Ratcliff, R., Thapar, A., & McKoon, G. (2004). A diffusion model analysis of the effects of aging on recognition memory. Journal of Memory and Language, 50(4), 408–424CrossRef Ratcliff, R., Thapar, A., & McKoon, G. (2004). A diffusion model analysis of the effects of aging on recognition memory. Journal of Memory and Language, 50(4), 408–424CrossRef
go back to reference Spiegelhalter, D. J., Best, N. G., Carlin, B. P., & Van der Linde, A. (2014). The deviance information criterion: 12 years on.Journal of the Royal Statistical Society: Series B: Statistical Methodology,485–493 Spiegelhalter, D. J., Best, N. G., Carlin, B. P., & Van der Linde, A. (2014). The deviance information criterion: 12 years on.Journal of the Royal Statistical Society: Series B: Statistical Methodology,485–493
go back to reference Thapar, A., Collishaw, S., Pine, D. S., & Thapar, A. K. (2012). Depression in adolescence. The Lancet, 379(9820), 1056–1067CrossRef Thapar, A., Collishaw, S., Pine, D. S., & Thapar, A. K. (2012). Depression in adolescence. The Lancet, 379(9820), 1056–1067CrossRef
go back to reference Treadway, M. T., Buckholtz, J. W., Schwartzman, A. N., Lambert, W. E., & Zald, D. H. (2009). Worth the ‘EEfRT’? The effort expenditure for rewards task as an objective measure of motivation and anhedonia.PloS one, 4(8), e6598 Treadway, M. T., Buckholtz, J. W., Schwartzman, A. N., Lambert, W. E., & Zald, D. H. (2009). Worth the ‘EEfRT’? The effort expenditure for rewards task as an objective measure of motivation and anhedonia.PloS one, 4(8), e6598
go back to reference Twenge, J. M., Joiner, T. E., Rogers, M. L., & Martin, G. N. (2018). Increases in depressive symptoms, suicide-related outcomes, and suicide rates among US adolescents after 2010 and links to increased new media screen time. Clinical Psychological Science, 6(1), 3–17CrossRef Twenge, J. M., Joiner, T. E., Rogers, M. L., & Martin, G. N. (2018). Increases in depressive symptoms, suicide-related outcomes, and suicide rates among US adolescents after 2010 and links to increased new media screen time. Clinical Psychological Science, 6(1), 3–17CrossRef
go back to reference White, C., Ratcliff, R., Vasey, M. W., & McKoon, G. (2010). Using diffusion models to understand clinical disorders. Journal of Mathematical Psychology, 54(1), 39–52CrossRefPubMedPubMedCentral White, C., Ratcliff, R., Vasey, M. W., & McKoon, G. (2010). Using diffusion models to understand clinical disorders. Journal of Mathematical Psychology, 54(1), 39–52CrossRefPubMedPubMedCentral
Metagegevens
Titel
Drift-Diffusion Model Reveals Impaired Reward-Based Perceptual Decision-Making Processes Associated with Depression in Late Childhood and Early Adolescent Girls
Auteurs
Riddhi J. Pitliya
Brady D. Nelson, Ph.D.
Greg Hajcak, Ph.D.
Jingwen Jin, Ph.D.
Publicatiedatum
09-06-2022
Uitgeverij
Springer US
Gepubliceerd in
Research on Child and Adolescent Psychopathology / Uitgave 11/2022
Print ISSN: 2730-7166
Elektronisch ISSN: 2730-7174
DOI
https://doi.org/10.1007/s10802-022-00936-y

Andere artikelen Uitgave 11/2022

Research on Child and Adolescent Psychopathology 11/2022 Naar de uitgave