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01-04-2015 | Uitgave 2/2015

Depressive symptoms and carotid intima–media thickness in South American Hispanics: results from the PREVENCION study

Tijdschrift:: Journal of Behavioral Medicine > Uitgave 2/2015

Auteurs:: Diana A. Chirinos, Josefina Medina-Lezama, Belissa Salinas-Najarro, William Arguelles, Maria M. Llabre, Neil Schneiderman, Roberto Paz-Manrique, Juan F. Bolanos, Zubair Khan, Julio A. Chirinos

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On behalf of the PREVENCION Investigators.

Abstract

This study aimed to: (1) examine the relationship between depressive symptoms and subclinical atherosclerosis, measured by carotid intima–media thickness (IMT); and, (2) Determine the moderating effect of gender in this relationship among South American Hispanics. We studied 496 adults enrolled in the population-based PREVENCION study. Carotid IMT was measured with high-resolution ultrasonography. Depressive symptoms were assessed using the Hospital Anxiety and Depression Scale. Mean carotid IMT was 0.66 mm. (SD = 0.17) and mean depression score was 5.6 (SD = 3.5). Depressive symptoms were not associated with carotid IMT (β = 0.04, p = 0.222) in multivariate analyses. A significant moderating effect of gender was found (β for interaction = 0.10, p = 0.030), resulting from a significant association between depressive symptoms and carotid IMT in men but not women. Depressive symptoms were associated with subclinical atherosclerosis in South American Hispanic men but not women after controlling for demographic characteristics and traditional cardiovascular risk factors.

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Titel: Depressive symptoms and carotid intima–media thickness in South American Hispanics: results from the PREVENCION study
Auteurs:: Diana A. Chirinos
Josefina Medina-Lezama
Belissa Salinas-Najarro
William Arguelles
Maria M. Llabre
Neil Schneiderman
Roberto Paz-Manrique
Juan F. Bolanos
Zubair Khan
Julio A. Chirinos
Publicatiedatum: 01-04-2015
DOI: https://doi.org/10.1007/s10865-014-9599-9
Uitgeverij: Springer US
Tijdschrift: Journal of Behavioral Medicine
Uitgave 2/2015
Print ISSN: 0160-7715
Elektronisch ISSN: 1573-3521

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