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Journal of Autism and Developmental Disorders

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25-07-2018 | Brief Report

Brief Report: Low Rates of Herpesvirus Detection in Blood of Individuals with Autism Spectrum Disorder and Controls

Auteurs: Thayne L. Sweeten, Lisa A. Croen, Gayle C. Windham, J. Dennis Odell, E. Gene Stubbs, Anthony R. Torres

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 1/2019

Abstract

Previous research indicates that infection, especially from viruses in the family Herpesviridae, may play a role in the etiology of some cases of autism spectrum disorder (ASD). Using a case-control design and the polymerase chain reaction with site-specific primers, we screened newborn and childhood blood samples for the presence of eight human herpesviruses. Herpesvirus DNA was detected in 4 of 225 ASD individuals and 2 of 235 controls, with the most frequently detected virus being HHV-6B. Although this study does not detect a significant ASD-Herpesviridae association, it is limited by the use of site-specific primers. We suggest that new techniques using bioinformatics to search next-generation sequencing databases will be more revealing of possible ASD-virus associations.

vorige artikel Brief Report: Sibling Feelings Toward their Brother or Sister With or Without Autism or Intellectual Disability

volgende artikel Brief Report: Does Social Functioning Moderate the Motor Outcomes of a Physical Activity Program for Children with Autism Spectrum Disorders—A Pilot Study

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Titel: Brief Report: Low Rates of Herpesvirus Detection in Blood of Individuals with Autism Spectrum Disorder and Controls
Auteurs: Thayne L. Sweeten
Lisa A. Croen
Gayle C. Windham
J. Dennis Odell
E. Gene Stubbs
Anthony R. Torres
Publicatiedatum: 25-07-2018
Uitgeverij: Springer US
Gepubliceerd in: Journal of Autism and Developmental Disorders / Uitgave 1/2019
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI: https://doi.org/10.1007/s10803-018-3691-x

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