Top

Journal of Autism and Developmental Disorders

Gepubliceerd in:

03-03-2017 | Original Paper

An Italian Prospective Experience on the Association Between Congenital Cytomegalovirus Infection and Autistic Spectrum Disorder

Auteurs: Francesca Garofoli, Giuseppina Lombardi, Simona Orcesi, Camilla Pisoni, Iolanda Mazzucchelli, Micol Angelini, Umberto Balottin, Mauro Stronati

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 5/2017

Abstract

The aim of this retrospective study, with prospective data collection, was to correlate congenital cytomegalovirus (CMV) infection with autism spectrum disorder (ASD) and to define its prevalence. Seventy proven congenitally-infected infants, born between 2007 and 2012, were referred to our centre for CMV diagnosis and follow-up, which consisted of a consolidated protocol allowing an early evaluation of autism. We considered four children 2-year old, two of whom, at the age of 3, were diagnosed with ASD demonstrating a 2–3 fold higher prevalence (2.86%), than that in general Italian population (0.66–1.36%).Our protocol enabled us to make the earliest diagnosis and highlight the role of the virus among other causes of autism, which may be a long term sequela of congenital CMV.

vorige artikel A Relationship Between Early Language Skills and Adult Autistic-Like Traits: Evidence from a Longitudinal Population-Based Study

volgende artikel Atypical Processing of Gaze Cues and Faces Explains Comorbidity between Autism Spectrum Disorder (ASD) and Attention Deficit/Hyperactivity Disorder (ADHD)

American Psychiatric Association (2000 and 2013). Diagnostic and statistical manual of mental disorders, 4th Ed, Text revision, DSM IV-TR. Washington, DC: American Psychiatric Association.

Amiel-Tison, C. (2002). Update of the Amiel-Tison neurologic assessment for the term neonate or at 40 weeks corrected age. Pediatric Neurology, 27, 196–212.CrossRefPubMed

Barbi, M., Binda, S., Caroppo, S., Calvario, A., Germinario, C., Bozzi, A., et al. (2006). Multicity Italian study of congenital cytomegalovirus infection. The Pediatric Infectious Disease Journal, 25, 156–159.CrossRefPubMed

Carbone, P. S., Norlin, C., & Young, P. C. (2016). Improving early identification and ongoing care of children with autism spectrum disorder. Pediatrics, 137(6), e20151850.CrossRefPubMed

Carigi, T., Muratori, F., Termine, C., Veggiotti, P., Derhemi, L., Di Nardo, R, et al. (2014). Diagnostic boundaries of autism disorder vs pervasive developmental disorder nos comparative observational study and literature review. Current Clinical Pharmacology, 9, 377–386.CrossRefPubMed

Chaudhary, T., Walch, E., Herold, B., Metze, B., Lejeune, A., Burkhardt, F., et al. (2013). Predictive and concurrent validity of standardized neurodevelopmental examinations by the Griffiths scales and Bayley scales of infant development II. Klinische Pädiatria, 225, 8–12.

Engman, M. L., Sundin, M., Miniscalco, C., Westerlund, J., Lewensohn-Fuchs, I., Gillberg, C., et al. (2015). Prenatal acquired cytomegalovirus infection should be considered in children with autism. Acta Paediatrica, 104, 792–795.CrossRefPubMed

Istituto Superiore di Sanità. http://www.iss.it/auti/index.php?lang=1?id=427&tipo=33&csss=002.

Ivarsson, S. A., Bjerre, I., Vegfors, P., & Ahlfors, K. (1990). Autism as one of several disabilities in two children with congenital cytomegalovirus infection. Neuropediatrics, 21, 102–103.CrossRefPubMed

James, S. H., & Kimberlin, D. W. (2016). Advances in the prevention and treatment of congenital cytomegalovirus infection. Current Opinion in Pediatrics, 28, 81–85.CrossRefPubMedPubMedCentral

Kadambari, S., Williams, E., Luck, S., Griffiths, P., & Sharland, M. (2011). Evidence based management guidelines for the detection and treatment of congenital CMV. Early Human Development, 87, 723–728.CrossRefPubMed

Karltorp, E., Löfkvist, U., Lewensohn-Fuchs, I., Lindström, K., Westblad, M. E., Fahnehjelm, K. T., et al. (2014). Impaired balance and neurodevelopmental disabilities among children with congenital cytomegalovirus infection. Acta Pædiatrica, 103, 1165–1173.CrossRefPubMed

Kenneson, A., & Cannon, M. J. (2007). Review and meta-analysis of the epidemiology of congenital cytomegalovirus (CMV) infection. Review in Medical Virology, 17, 253–276.CrossRef

Le Couteur, A., Lord, C., & Rutter, M. (2003). The Autism diagnostic interview: Revised (ADI-R). Los Angeles: Western Psychological Services.

Libbey, J. E., Sweeten, T. L., McMahon, W. M., & Fujinami, R. S. (2005). Autistic disorder and viral infections. Journal of Neurovirology, 11, 1–10.CrossRefPubMed

Lombardi, G., Garofoli, F., Villani, P., Tizzoni, M., Angelini, M., Cusato, M., et al. (2009). Oral valganciclovir treatment in newborns with symptomatic congenital cytomegalovirus infection. European Journal of Clinical Microbiology & Infectious Diseases, 28, 1465–1470.CrossRef

Lord, C., Rutter, M., DiLavore P, P. C., & Risi, S. (2002) Autism diagnostic observation schedule. Los Angeles: Western Psychological Services.

Luyster, R., Gotham, K., Guthrie, W., Coffing, M., Petrak, R., Pierce, K., et al. (2009). The autism diagnostic observation schedule-toddler module: a new module of a standardized diagnostic measure for autism spectrum disorders. Journal of Autism Development Disorder, 39, 1305–1320.CrossRef

Markowitz, P. I. (1983). Autism in a child with congenital cytomegalovirus infection. Journal of Autism Development Disorder, 13, 249–253.CrossRef

Miodovnik, A., Harstad, E., Sideridis, G. & Huntington, N. (2015). Timing of the diagnosis of attention-deficit/hyperactivity disorder and autism spectrum disorder. Pediatrics 2015, 136, e830–e837.CrossRefPubMed

Odeberg, J., Wolmer, N., Falci, S., Westergren, M., & Seiger, A. (2006). Human cytomegalovirus inhibits neuronal differentiation and induces apoptosis in human neural precursor cells. Journal Virology, 80, 8929–8939.CrossRef

Sakamoto, A., Moriuchi, H., Matsuzaki, J., Motoyama, K., & Moriuchi, M. (2015). Retrospective diagnosis of congenital cytomegalovirus infection in children with autism spectrum disorder but no other major neurologic deficit. Brain Development, 37, 200–205.CrossRefPubMed

Sparrow, S.S., Cicchetti, D.V. & Balla, D.A. (2005). Vineland adaptive behaviour scales. 2nd Ed. San Antonio, TX: Pearson Education Inc.

Stagg, S. D., Linnell, K. J., & Heaton, P. (2014). Investigating eye movement patterns, language, and social ability in children with autism spectrum disorder. Development and Psychopathology, 26, 529–537.CrossRefPubMed

Steiner, A. M., Goldsmith, T. R., Snow, A. V., & Chawarska, K. (2012). Practitioner’s guide to assessment of autism spectrum disorders in infants and toddlers. Journal of Autism Development Disorder, 42, 1183–1196.CrossRef

Stubbs, E. G., Ash, E., & Williams, C. P. (1984). Autism and congenital cytomegalovirus. Journal of Autism Development Disorder, 14, 183–189.CrossRef

Swanson, E. C., & Schleiss, M. R. (2013). Congenital Cytomegalovirus Infection: New prospects for prevention and therapy: For pediatric clinics of North America: Advances in evaluation, diagnosis and treatment of pediatric infectious disease. Pediatric Clinics North America, 60, 335–349.CrossRef

Sweeten, T. L., Posey, D. J., & McDougle, C. J. (2004). Brief report: autistic disorder in three children with cytomegalovirus infection. Journal of Autism Development Disorder, 34, 583–586.CrossRef

Volkmar, F. R., Sparrow, S. S., Goudreau, D., Cicchetti, D. V., Paul, R., & Cohen, D. J. (1987). Social deficits in autism: an operational approach using the Vineland Adaptive Behavior Scales. Journal of the American Academy of Child and Adolescent Psychiatry, 26, 156–161.CrossRefPubMed

Yamashita, Y., Fujimoto, C., Nakajima, E., Isagai, T., & Matsuishi, T. (2003). Possible association between congenital cytomegalovirus infection and autistic disorder. Journal of Autism Development Disorder, 33, 455–459.CrossRef

Titel: An Italian Prospective Experience on the Association Between Congenital Cytomegalovirus Infection and Autistic Spectrum Disorder
Auteurs: Francesca Garofoli
Giuseppina Lombardi
Simona Orcesi
Camilla Pisoni
Iolanda Mazzucchelli
Micol Angelini
Umberto Balottin
Mauro Stronati
Publicatiedatum: 03-03-2017
Uitgeverij: Springer US
Gepubliceerd in: Journal of Autism and Developmental Disorders / Uitgave 5/2017
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI: https://doi.org/10.1007/s10803-017-3050-3

Bohn Stafleu van Loghum

Deel dit onderdeel of sectie (kopieer de link)

Abstract

Log in om toegang te krijgen

Andere artikelen Uitgave 5/2017

Atypical Processing of Gaze Cues and Faces Explains Comorbidity between Autism Spectrum Disorder (ASD) and Attention Deficit/Hyperactivity Disorder (ADHD)

Brief Report: Characteristics of preschool children with ASD vary by ascertainment

“Set in Stone” or “Ray of Hope”: Parents’ Beliefs About Cause and Prognosis After Genomic Testing of Children Diagnosed with ASD

Comprehensive Psychometric Analysis of the Eyberg Child Behavior Inventory in Children with Autism Spectrum Disorder

Brief Report: An Exploratory Study of the Diagnostic Reliability for Autism Spectrum Disorder

Brief Report: Examination of Correlates of Adaptive Behavior in Children with HFASD using the BASC-2 Parent Rating Scale