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Gepubliceerd in: Journal of Autism and Developmental Disorders 7/2010

01-07-2010 | Original Paper

Williams Syndrome and Memory: A Neuroanatomic and Cognitive Approach

Auteurs: Adriana Sampaio, Nuno Sousa, Montse Férnandez, Cristiana Vasconcelos, Martha E. Shenton, Óscar F. Gonçalves

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 7/2010

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Abstract

Williams Syndrome (WS) is described as displaying a dissociation within memory systems. As the integrity of hippocampal formation (HF) is determinant for memory performance, we examined HF volumes and its association with memory measures in a group of WS and in a typically development group. A significantly reduced intracranial content was found in WS, despite no differences were observed for HF absolute volumes between groups. When volumes were normalized, left HF was increased in WS. Moreover, a lack of the normal right > left HF asymmetry was observed in WS. No positive correlations were found between volumetric and neurocognitive data in WS. In sum, a relative enlargement of HF and atypical patterns of asymmetry suggest abnormal brain development in WS.
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Metagegevens
Titel
Williams Syndrome and Memory: A Neuroanatomic and Cognitive Approach
Auteurs
Adriana Sampaio
Nuno Sousa
Montse Férnandez
Cristiana Vasconcelos
Martha E. Shenton
Óscar F. Gonçalves
Publicatiedatum
01-07-2010
Uitgeverij
Springer US
Gepubliceerd in
Journal of Autism and Developmental Disorders / Uitgave 7/2010
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI
https://doi.org/10.1007/s10803-010-0940-z

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