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18-07-2015

The mediating role of interpersonal conflict at work in the relationship between negative affectivity and biomarkers of stress

Auteurs: Damiano Girardi, Alessandra Falco, Alessandro De Carlo, Paula Benevene, Manola Comar, Enrico Tongiorgi, Giovanni Battista Bartolucci

Gepubliceerd in: Journal of Behavioral Medicine | Uitgave 6/2015

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Abstract

This study examined the association between interpersonal conflict at work (ICW) and serum levels of three possible biomarkers of stress, namely the pro-inflammatory cytokines Interleukin 1 beta (IL-1β), Interleukin 12 (IL-12), and Interleukin 17 (IL-17). Additionally, this study investigated the role of negative affectivity (NA) in the relationship between ICW and the pro-inflammatory cytokines. Data from 121 employees in an Italian healthcare organization were analyzed using structural equation modeling. Results showed that ICW was positively associated with IL-1β, IL-12, and IL-17, after controlling for the effect of gender. Moreover, ICW completely mediated the relationship between NA and the pro-inflammatory cytokines IL-1β, IL-12, and IL-17. This mediating effect was significant after controlling for the effect of gender. Overall, this study suggests that work-related stress may be associated with biomarkers of inflammation, and that negative affectivity may influence the stress process affecting the exposure to psychosocial stressors.
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Metagegevens
Titel
The mediating role of interpersonal conflict at work in the relationship between negative affectivity and biomarkers of stress
Auteurs
Damiano Girardi
Alessandra Falco
Alessandro De Carlo
Paula Benevene
Manola Comar
Enrico Tongiorgi
Giovanni Battista Bartolucci
Publicatiedatum
18-07-2015
Uitgeverij
Springer US
Gepubliceerd in
Journal of Behavioral Medicine / Uitgave 6/2015
Print ISSN: 0160-7715
Elektronisch ISSN: 1573-3521
DOI
https://doi.org/10.1007/s10865-015-9658-x