Top

Optie A:

Klik op de rechtermuisknop op de link en selecteer de optie “linkadres kopiëren”
Optie B:

Deel de link per e-mail
Link delen

vorige artikel “We get what we deserve”: the belief in a just ...

volgende artikel Cognitive-behavioral intervention to promote sm...

Tip

Swipe om te navigeren naar een ander artikel

18-07-2015 | Uitgave 6/2015

The mediating role of interpersonal conflict at work in the relationship between negative affectivity and biomarkers of stress

Tijdschrift:: Journal of Behavioral Medicine > Uitgave 6/2015

Auteurs:: Damiano Girardi, Alessandra Falco, Alessandro De Carlo, Paula Benevene, Manola Comar, Enrico Tongiorgi, Giovanni Battista Bartolucci

» Toegang tot de volledige tekst krijgen

Abstract

This study examined the association between interpersonal conflict at work (ICW) and serum levels of three possible biomarkers of stress, namely the pro-inflammatory cytokines Interleukin 1 beta (IL-1β), Interleukin 12 (IL-12), and Interleukin 17 (IL-17). Additionally, this study investigated the role of negative affectivity (NA) in the relationship between ICW and the pro-inflammatory cytokines. Data from 121 employees in an Italian healthcare organization were analyzed using structural equation modeling. Results showed that ICW was positively associated with IL-1β, IL-12, and IL-17, after controlling for the effect of gender. Moreover, ICW completely mediated the relationship between NA and the pro-inflammatory cytokines IL-1β, IL-12, and IL-17. This mediating effect was significant after controlling for the effect of gender. Overall, this study suggests that work-related stress may be associated with biomarkers of inflammation, and that negative affectivity may influence the stress process affecting the exposure to psychosocial stressors.

Log in om toegang te krijgen

Hier inloggen

Met onderstaand(e) abonnement(en) heeft u direct toegang:

BSL Psychologie Totaal

Met BSL Psychologie Totaal blijft u als professional steeds op de hoogte van de nieuwste ontwikkelingen binnen uw vak. Met het online abonnement heeft u toegang tot een groot aantal boeken, protocollen, vaktijdschriften en e-learnings op het gebied van psychologie en psychiatrie. Zo kunt u op uw gemak en wanneer het u het beste uitkomt verdiepen in uw vakgebied.

Meer informatie

Acosta-Rodriguez, E. V., Napolitani, G., Lanzavecchia, A., & Sallusto, F. (2007). Interleukins 1β and 6 but not transforming growth factor-β are essential for the differentiation of interleukin 17–producing human T helper cells. Nature Immunology, 8, 942–949. doi: 10.1038/ni1496 CrossRefPubMed

Aldao, A., & Nolen-Hoeksema, S. (2010). Specificity of cognitive emotion regulation strategies: A transdiagnostic examination. Behaviour Research and Therapy, 48, 974–983. doi: 10.1016/j.brat.2010.06.002 CrossRefPubMed

Aquino, K., Grover, S. L., Bradfield, M., & Allen, D. G. (1999). The effects of negative affectivity, hierarchical status, and self-determination on workplace victimization. Academy of Management Journal, 42, 260–272. doi: 10.2307/256918 CrossRef

Arnsten, A. F. T. (2009). Stress signalling pathways that impair prefrontal cortex structure and function. Nature Reviews Neuroscience, 10, 410–422. doi: 10.1038/nrn2648 PubMedCentralCrossRefPubMed

Baumeister, R. F., & Leary, M. R. (1995). The need to belong: Desire for interpersonal attachments as a fundamental human motivation. Psychological Bulletin, 117, 497–529. doi: 10.1037/0033-2909.117.3.497 CrossRefPubMed

Beal, D. J., Weiss, H. M., Barros, E., & MacDermid, S. M. (2005). An episodic process model of affective influences on performance. Journal of Applied Psychology, 90, 1054–1068. doi: 10.1037/0021-9010.90.6.1054 CrossRefPubMed

Bolger, N., & Schilling, E. A. (1991). Personality and the problems of everyday life: The role of neuroticism in exposure and reactivity to daily stressors. Journal of Personality, 59, 355–386. doi: 10.1111/j.1467-6494.1991.tb00253.x CrossRefPubMed

Bolger, N., & Zuckerman, A. (1995). A framework for studying personality in the stress process. Journal of Personality and Social Psychology, 69, 890–902. doi: 10.1037/0022-3514.69.5.890 CrossRefPubMed

Brief, A. P., Burke, M. J., George, J. M., Robinson, B. S., & Webster, J. (1988). Should negative affectivity remain an unmeasured variable in the study of job stress? Journal of Applied Psychology, 73, 193–198. doi: 10.1037/0021-9010.73.2.193 CrossRefPubMed

Brosschot, J. F., Gerin, W., & Thayer, J. F. (2006). The perseverative cognition hypothesis: A review of worry, prolonged stress-related physiological activation, and health. Journal of Psychosomatic Research, 60, 113–124. doi: 10.1016/j.jpsychores.2005.06.074 CrossRefPubMed

Brown, T. A. (2006). Confirmatory factor analysis for applied research. New York, NY: Guilford Press.

Bryant, F. B., & Satorra, A. (2012). Principles and practice of scaled difference Chi square testing. Structural Equation Modeling, 19, 372–398. doi: 10.1080/10705511.2012.687671 CrossRef

Burke, M. J., Brief, A. P., & George, J. M. (1993). The role of negative affectivity in understanding relations between self-reports of stressors and strains: A comment on the applied psychology literature. Journal of Applied Psychology, 78, 402–412. doi: 10.1037/0021-9010.78.3.402 CrossRefPubMed

Carlino, D., Leone, E., Di Cola, F., Baj, G., Marin, R., Dinelli, G., Tongiorgi, E., & De Vanna, M. (2011). Low serum truncated-BDNF isoform correlates with higher cognitive impairment in schizophrenia. Journal of Psychiatric Research, 45, 273–279. doi: 10.1016/j.jpsychires.2010.06.012 CrossRefPubMed

Chen, Y., Jiang, T., Chen, P., Ouyang, J., Xu, G., Zeng, Z., & Sun, Y. (2011). Emerging tendency towards autoimmune process in major depressive patients: A novel insight from Th17 cells. Psychiatry Research, 188, 224–230. doi: 10.1016/j.psychres.2010.10.029 CrossRefPubMed

Clark, M. A., Michel, J. S., Zhdanova, L., Pui, S. Y., & Baltes, B. B. (2014). All work and no play? A meta-analytic examination of the correlates and outcomes of workaholism. Journal of Management. doi: 10.1177/0149206314522301

Comar, M., Zanotta, N., Bonotti, A., Tognon, M., Negro, C., Cristaudo, A., & Bovenzi, M. (2014). Increased levels of C–C chemokine RANTES in asbestos exposed workers and in malignant mesothelioma patients from an hyperendemic area. PLoS One, 9, e104848. doi: 10.1371/journal.pone.0104848 PubMedCentralCrossRefPubMed

Copertaro, A., Bracci, M., Gesuita, R., Carle, F., Amati, M., Baldassari, M., Mocchegiani, E., & Santarelli, L. (2011). Influence of shift-work on selected immune variables in nurses. Industrial Health, 49, 597–604. doi: 10.2486/indhealth.MS1210 CrossRefPubMed

Dal Corso, L., Floretta, P., Falco, A., Benevene, P., & De Carlo, A. (2013). The repertory grid technique in a research-intervention on work-related stress. TPM—Testing, Psychometrics, Methodology in Applied Psychology, 20, 155–168. doi: 10.4473/TPM20.2.4

De Carlo, N. A., Falco, A., & Capozza, D. (2008). Test di valutazione del rischio stress lavoro-correlato nella prospettiva del benessere organizzativo, Q-Bo. Milano: FrancoAngeli. doi: 10.3280/TEST4000_2

Eaton, R. J., & Bradley, G. (2008). The role of gender and negative affectivity in stressor appraisal and coping selection. International Journal of Stress Management, 15, 94–115. doi: 10.1037/1072-5245.15.1.94 CrossRef

Falco, A., Girardi, D., Kravina, L., Trifiletti, E., Bartolucci, G. B., Capozza, D., & De Carlo, N. A. (2013a). The mediating role of psychophysic strain in the relationship between workaholism, job performance, and sickness absence: A longitudinal study. Journal of Occupational and Environmental Medicine, 55, 1255–1261. doi: 10.1097/JOM.0000000000000007 CrossRefPubMed

Falco, A., Girardi, D., Marcuzzo, G., De Carlo, A., & Bartolucci, G. B. (2013b). Work stress and negative affectivity: A multi-method study. Occupational Medicine, 63, 341–347. doi: 10.1093/occmed/kqt054 CrossRefPubMed

Falvo, R., Visintin, E. P., Capozza, D., Falco, A., & De Carlo, A. (2013). The relationships among workaholism, proactivity, and locomotion in a work setting. Social Behavior and Personality: An International Journal, 41, 1557–1569. doi: 10.2224/sbp.2013.41.9.1557 CrossRef

Fortunato, V. J., Jex, S. M., & Heinish, D. A. (1999). An examination of the discriminant validity of the strain-free negative affectivity scale. Journal of Occupational and Organizational Psychology, 72, 503–522. doi: 10.1348/096317999166815 CrossRef

Ganster, D. C., & Rosen, C. C. (2013). Work stress and employee health: A multidisciplinary review. Journal of Management, 39, 1085–1122. doi: 10.1177/0149206313475815 CrossRef

Geurts, S. A. E., & Sonnentag, S. (2006). Recovery as an explanatory mechanism in the relation between acute stress reactions and chronic health impairment. Scandinavian Journal of Work, Environment & Health, 32, 482–492. doi: 10.5271/sjweh.1053 CrossRef

Girardi, D., Falco, A., Dal Corso, L., Kravina, L., & De Carlo, A. (2011). Interpersonal conflict and perceived work stress: The role of negative affectivity. TPM—Testing, Psychometrics, Methodology in Applied Psychology, 18, 257–273.

Haider, D. G., Leuchten, N., Schaller, G., Gouya, G., Kolodjaschna, J., Schmetterer, L., Kapiotis, S., & Wolzt, M. (2006). C-reactive protein is expressed and secreted by peripheral blood mononuclear cells. Clinical and Experimental Immunology, 146, 533–539. doi: 10.1111/j.1365-2249.2006.03224.x PubMedCentralCrossRefPubMed

Hänsel, A., Hong, S., Cámara, R. J. A., & von Känel, R. (2010). Inflammation as a psychophysiological biomarker in chronic psychosocial stress. Neuroscience and Biobehavioral Reviews, 35, 115–121. doi: 10.1016/j.neubiorev.2009.12.012 CrossRefPubMed

Hickman, R. J., Khambaty, T., & Stewart, J. C. (2014). C-reactive protein is elevated in atypical but not nonatypical depression: Data from the National Health and Nutrition Examination Survey (NHANES) 1999–2004. Journal of Behavioral Medicine, 37, 621–629. doi: 10.1007/s10865-013-9510-0 CrossRefPubMed

Hong, M., Zheng, J., Ding, Z.-Y., Chen, J.-H., Yu, L., Niu, Y., Hua, Y., & Wang, L.-L. (2013). Imbalance between Th17 and Treg cells may play an important role in the development of chronic unpredictable mild stress-induced depression in mice. NeuroImmunoModulation, 20, 39–50. doi: 10.1159/000343100 CrossRefPubMed

Howren, M. B., Lamkin, D. M., & Suls, J. (2009). Associations of depression with C-reactive protein, IL-1, and IL-6: A meta-analysis. Psychosomatic Medicine, 71, 171–186. doi: 10.1097/PSY.0b013e3181907c1b CrossRefPubMed

Hsieh, C. S., Macatonia, S. E., Tripp, C. S., Wolf, S. F., O’Garra, A., & Murphy, K. M. (1993). Development of TH1 CD4 + T cells through IL-12 produced by Listeria-induced macrophages. Science, 260, 547–549. doi: 10.1126/science.8097338 CrossRefPubMed

Ilies, R., Johnson, M. D., Judge, T. A., & Keeney, J. (2011). A within-individual study of interpersonal conflict as a work stressor: Dispositional and situational moderators. Journal of Organizational Behavior, 32, 44–64. doi: 10.1002/job.677 CrossRef

Jex, S. M., Adams, G. A., & Ehler, M. L. (2002). Assessing the role of negative affectivity in occupational stress research: Does gender make a difference? In D. L. Nelson & R. J. Burke (Eds.), Gender, work stress, and health (pp. 71–84). Washington: American Psychological Association. doi: 10.1037/10467-005 CrossRef

Johnson, T. V., Abbasi, A., & Master, V. A. (2013). Systematic review of the evidence of a relationship between chronic psychosocial stress and C-reactive protein. Molecular Diagnosis and Therapy, 17, 147–164. doi: 10.1007/s40291-013-0026-7 CrossRefPubMed

Jöreskog, K. G., & Sörbom, D. (2006). LISREL (Version 8.80) [Computer software]. Lincolnwood, IL: Scientific Software International.

Juster, R.-P., McEwen, B. S., & Lupien, S. J. (2010). Allostatic load biomarkers of chronic stress and impact on health and cognition. Neuroscience and Biobehavioral Reviews, 35, 2–16. doi: 10.1016/j.neubiorev.2009.10.002 CrossRefPubMed

Kim, Y.-K., Suh, I.-B., Kim, H., Han, C.-S., Lim, C.-S., Choi, S.-H., & Licinio, J. (2002). The plasma levels of interleukin-12 in schizophrenia, major depression, and bipolar mania: Effects of psychotropic drugs. Molecular Psychiatry, 7, 1107–1114. doi: 10.1038/sj.mp.4001084 CrossRefPubMed

Koo, J. W., & Duman, R. S. (2009). Evidence for IL-1 receptor blockade as a therapeutic strategy for the treatment of depression. Current Opinion in Investigational Drugs, 10, 664–671. PubMedCentralPubMed

Kravina, L., Falco, A., De Carlo, N. A., Andreassen, C. S., & Pallesen, S. (2014). Workaholism and work engagement in the family: The relationship between parents and children as a risk factor. European Journal of Work and Organizational Psychology, 23, 875–883. doi: 10.1080/1359432X.2013.832208 CrossRef

Kravina, L., Falco, A., Girardi, D., & De Carlo, N. A. (2010). Workaholism among management and workers in an Italian cooperative enterprise. TPM—Testing, Psychometrics, Methodology in Applied Psychology, 17, 201–216.

Kubera, M., Obuchowicz, E., Goehler, L., Brzeszcz, J., & Maes, M. (2011). In animal models, psychosocial stress-induced (neuro)inflammation, apoptosis and reduced neurogenesis are associated to the onset of depression. Progress in Neuro-Psychopharmacology and Biological Psychiatry, 35, 744–759. doi: 10.1016/j.pnpbp.2010.08.026 CrossRefPubMed

Lee, K.-M., & Kim, Y.-K. (2006). The role of IL-12 and TGF-β1 in the pathophysiology of major depressive disorder. International Immunopharmacology, 6, 1298–1304. doi: 10.1016/j.intimp.2006.03.015 CrossRefPubMed

Leonard, B., & Maes, M. (2012). Mechanistic explanations how cell-mediated immune activation, inflammation and oxidative and nitrosative stress pathways and their sequels and concomitants play a role in the pathophysiology of unipolar depression. Neuroscience and Biobehavioral Reviews, 36, 764–785. doi: 10.1016/j.neubiorev.2011.12.005 CrossRefPubMed

Little, T. D., Rhemtulla, M., Gibson, K., & Schoemann, A. M. (2013). Why the items versus parcels controversy needn’t be one. Psychological Methods, 18, 285–300. doi: 10.1037/a0033266 PubMedCentralCrossRefPubMed

MacKinnon, D. P. (2008). Introduction to statistical mediation analysis. New York, NY: Lawrence Erlbaum.

Meier, L. L., Gross, S., Spector, P. E., & Semmer, N. K. (2013). Relationship and task conflict at work: Interactive short-term effects on angry mood and somatic complaints. Journal of Occupational Health Psychology, 18, 144–156. doi: 10.1037/a0032090 CrossRefPubMed

Meier, L. L., Semmer, N. K., & Gross, S. (2014). The effect of conflict at work on well-being: Depressive symptoms as a vulnerability factor. Work and Stress, 28, 31–48. doi: 10.1080/02678373.2013.876691 CrossRef

Miossec, P., & Kolls, J. K. (2012). Targeting IL-17 and T _H17 cells in chronic inflammation. Nature Reviews Drug Discovery, 11, 763–776. doi: 10.1038/nrd3794 CrossRefPubMed

Nixon, A. E., Mazzola, J. J., Bauer, J., Krueger, J. R., & Spector, P. E. (2011). Can work make you sick? A meta-analysis of the relationships between job stressors and physical symptoms. Work and Stress, 25, 1–22. doi: 10.1080/02678373.2011.569175 CrossRef

Oliver, J. E., Mansell, A., & Jose, P. E. (2010). A longitudinal study of the role of negative affectivity on the work stressor–strain process. International Journal of Stress Management, 17, 56–77. doi: 10.1037/a0017696 CrossRef

Parkes, K. R. (1990). Coping, negative affectivity, and the work environment: Additive and interactive predictors of mental health. Journal of Applied Psychology, 75, 399–409. doi: 10.1037/0021-9010.75.4.399 CrossRefPubMed

Podsakoff, P. M., MacKenzie, S. B., & Podsakoff, N. P. (2012). Sources of method bias in social science research and recommendations on how to control it. Annual Review of Psychology, 63, 539–569. doi: 10.1146/annurev-psych-120710-100452 CrossRefPubMed

Prather, A. A., Carroll, J. E., Fury, J. M., McDade, K. K., Ross, D., & Marsland, A. L. (2009). Gender differences in stimulated cytokine production following acute psychological stress. Brain, Behavior, and Immunity, 23, 622–628. doi: 10.1016/j.bbi.2008.11.004 PubMedCentralCrossRefPubMed

Ramey, S. L., Downing, N. R., Franke, W. D., Perkhounkova, Y., & Alasagheirin, M. H. (2012). Relationships among stress measures, risk factors, and inflammatory biomarkers in law enforcement officers. Biological Research for Nursing, 14, 16–26. doi: 10.1177/1099800410396356 PubMedCentralCrossRefPubMed

Ricci, S., Massoni, F., Di Meo, M., Petrone, L., Canitano, N., Ippoliti, F., & Cinti, M. E. (2013). Correlazione fra misure di stress, indicatori di natura bioumorale e considerazioni medico-legali [Correlation among measures of stress, indicators of biohumoral nature and medico-legal considerations]. Rivista di Psichiatria, 48, 113–120. doi: 10.1708/1272.14035 PubMed

Rohleder, N., Schommer, N. C., Hellhammer, D. H., Engel, R., & Kirschbaum, C. (2001). Sex differences in glucocorticoid sensitivity of proinflammatory cytokine production after psychosocial stress. Psychosomatic Medicine, 63, 966–972. CrossRefPubMed

Segerstrom, S. C., & Miller, G. E. (2004). Psychological stress and the human immune system: A meta-analytic study of 30 years of inquiry. Psychological Bulletin, 130, 601–630. doi: 10.1037/0033-2909.130.4.601 PubMedCentralCrossRefPubMed

Shaashua, L., Sominsky, L., Levi, B., Sorski, L., Reznick, M., Page, G. G., & Ben-Eliyahu, S. (2012). In vivo suppression of plasma IL-12 levels by acute and chronic stress paradigms: Potential mediating mechanisms and sex differences. Brain, Behavior, and Immunity, 26, 996–1005. doi: 10.1016/j.bbi.2012.05.012 PubMedCentralCrossRefPubMed

Singhal, G., Jaehne, E. J., Corrigan, F., Toben, C., & Baune, B. T. (2014). Inflammasomes in neuroinflammation and changes in brain function: A focused review. Frontiers in Neuroscience, 8, 315. doi: 10.3389/fnins.2014.00315 PubMedCentralCrossRefPubMed

Slavich, G. M., & Irwin, M. R. (2014). From stress to inflammation and major depressive disorder: A social signal transduction theory of depression. Psychological Bulletin, 140, 774–815. doi: 10.1037/a0035302 PubMedCentralCrossRefPubMed

Sonnentag, S., Binnewies, C., & Mojza, E. J. (2008). “Did you have a nice evening?” A day-level study on recovery experiences, sleep, and affect. Journal of Applied Psychology, 93, 674–684. doi: 10.1037/0021-9010.93.3.674 CrossRefPubMed

Spector, P. E., & Bruk-Lee, V. (2008). Conflict, health, and well-being. In C. K. W. De Dreu & M. J. Gelfand (Eds.), The psychology of conflict and conflict management in organizations (pp. 267–288). New York, NY: Lawrence Erlbaum.

Spector, P. E., Chen, P. Y., & O’Connell, B. J. (2000a). A longitudinal study of relations between job stressors and job strains while controlling for prior negative affectivity and strains. Journal of Applied Psychology, 85, 211–218. doi: 10.1037/0021-9010.85.2.211 CrossRefPubMed

Spector, P. E., & Jex, S. M. (1998). Development of four self-report measures of job stressors and strain: Interpersonal Conflict at Work Scale, Organizational Constraints Scale, Quantitative Workload Inventory, and Physical Symptoms Inventory. Journal of Occupational Health Psychology, 3, 356–367. doi: 10.1037/1076-8998.3.4.356 CrossRefPubMed

Spector, P. E., Zapf, D., Chen, P. Y., & Frese, M. (2000b). Why negative affectivity should not be controlled in job stress research: Don’t throw out the baby with the bath water. Journal of Organizational Behavior, 21, 79–95. doi: 10.1002/(SICI)1099-1379(200002)21:1<79:AID-JOB964>3.0.CO;2-G CrossRef

Steinman, L. (2007). A brief history of T _H17, the first major revision in the T _H1/T _H2 hypothesis of T cell-mediated tissue damage. Nature Medicine, 13, 139–145. doi: 10.1038/nm1551 CrossRefPubMed

Steptoe, A., Hamer, M., & Chida, Y. (2007). The effects of acute psychological stress on circulating inflammatory factors in humans: A review and meta-analysis. Brain, Behavior, and Immunity, 21, 901–912. doi: 10.1016/j.bbi.2007.03.011 CrossRefPubMed

Tofighi, D., & MacKinnon, D. P. (2011). RMediation: An R package for mediation analysis confidence intervals. Behavior Research Methods, 43, 692–700. doi: 10.3758/s13428-011-0076-x PubMedCentralCrossRefPubMed

Watson, D., & Clark, L. A. (1984). Negative affectivity: The disposition to experience aversive emotional states. Psychological Bulletin, 96, 465–490. doi: 10.1037/0033-2909.96.3.465 CrossRefPubMed

Watson, D., & Pennebaker, J. W. (1989). Health complaints, stress, and distress: Exploring the central role of negative affectivity. Psychological Review, 96, 234–254. doi: 10.1037/0033-295X.96.2.234 CrossRefPubMed

Yoon, H.-S., Lee, K.-M., & Kang, D. (2014). Intercorrelation between immunological biomarkers and job stress indicators among female nurses: A 9-month longitudinal study. Frontiers in Public Health, 2, 157. doi: 10.3389/fpubh.2014.00157 PubMedCentralCrossRefPubMed

Titel: The mediating role of interpersonal conflict at work in the relationship between negative affectivity and biomarkers of stress
Auteurs:: Damiano Girardi
Alessandra Falco
Alessandro De Carlo
Paula Benevene
Manola Comar
Enrico Tongiorgi
Giovanni Battista Bartolucci
Publicatiedatum: 18-07-2015
DOI: https://doi.org/10.1007/s10865-015-9658-x
Uitgeverij: Springer US
Tijdschrift: Journal of Behavioral Medicine
Uitgave 6/2015
Print ISSN: 0160-7715
Elektronisch ISSN: 1573-3521

Bohn Stafleu van Loghum

Deel dit onderdeel of sectie (kopieer de link)

Tip

Swipe om te navigeren naar een ander artikel

Abstract

Log in om toegang te krijgen

Met onderstaand(e) abonnement(en) heeft u direct toegang:

BSL Psychologie Totaal

Andere artikelen Uitgave 6/2015

For better or for worse: a longitudinal study on dyadic coping and quality of life among couples with a partner suffering from COPD

Cognitive-behavioral intervention to promote smoking cessation for pregnant and postpartum inner city women

“We get what we deserve”: the belief in a just world and its health consequences for Blacks

Does colorectal cancer risk perception predict screening behavior? A systematic review and meta-analysis

Attributing discrimination to weight: associations with well-being, self-care, and disease status in patients with type 2 diabetes mellitus

Do brief alcohol interventions reduce tobacco use among adolescents and young adults? A systematic review and meta-analysis