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18-07-2015 | Uitgave 6/2015

The mediating role of interpersonal conflict at work in the relationship between negative affectivity and biomarkers of stress

Tijdschrift:: Journal of Behavioral Medicine > Uitgave 6/2015

Auteurs:: Damiano Girardi, Alessandra Falco, Alessandro De Carlo, Paula Benevene, Manola Comar, Enrico Tongiorgi, Giovanni Battista Bartolucci

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Abstract

This study examined the association between interpersonal conflict at work (ICW) and serum levels of three possible biomarkers of stress, namely the pro-inflammatory cytokines Interleukin 1 beta (IL-1β), Interleukin 12 (IL-12), and Interleukin 17 (IL-17). Additionally, this study investigated the role of negative affectivity (NA) in the relationship between ICW and the pro-inflammatory cytokines. Data from 121 employees in an Italian healthcare organization were analyzed using structural equation modeling. Results showed that ICW was positively associated with IL-1β, IL-12, and IL-17, after controlling for the effect of gender. Moreover, ICW completely mediated the relationship between NA and the pro-inflammatory cytokines IL-1β, IL-12, and IL-17. This mediating effect was significant after controlling for the effect of gender. Overall, this study suggests that work-related stress may be associated with biomarkers of inflammation, and that negative affectivity may influence the stress process affecting the exposure to psychosocial stressors.

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Titel: The mediating role of interpersonal conflict at work in the relationship between negative affectivity and biomarkers of stress
Auteurs:: Damiano Girardi
Alessandra Falco
Alessandro De Carlo
Paula Benevene
Manola Comar
Enrico Tongiorgi
Giovanni Battista Bartolucci
Publicatiedatum: 18-07-2015
DOI: https://doi.org/10.1007/s10865-015-9658-x
Uitgeverij: Springer US
Tijdschrift: Journal of Behavioral Medicine
Uitgave 6/2015
Print ISSN: 0160-7715
Elektronisch ISSN: 1573-3521

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