Psychological dysregulation is a complex and multidimensional construct encompassing cognitive, emotional, and behavioral dimensions. Research on psychological dysregulation emphasizes its importance in relation to several psychological disorders. However, assessing psychological dysregulation is often problematic because many of the existing instruments address a specific dysregulation dimension at a time, predominantly emotional dysregulation. The Abbreviated Dysregulation Inventory (ADI) was developed to assess three dimensions of psychological dysregulation: emotional, cognitive and behavioral. This study’s goal was to analyze the factor structure, internal consistency, and validity in relation to external variables of the Portuguese version of the ADI in a sample of 511 adolescents aged between 12 and 19 years old. The 3-factor solution was confirmed, and high internal consistency was found for the three subscales. Peculiar findings on the cognitive dysregulation subscale raised issues addressed in the discussion section. Results indicated that dysregulation associates positively with aggressive behavior and negatively with quality of life. Age and gender presented small influence on the cognitive and behavioral subscales scores, respectively. Findings suggested that ADI can be a valuable self-report measure to assess cognitive, behavioral or emotional dysregulation in youths, within research and psychological intervention settings.