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Gepubliceerd in: Neuropraxis 4/2012

01-09-2012 | Artikelen

Symptoomdimensiescores zijn geassocieerd met progressieve hersenvolumeveranderingen bij schizofrenie

Auteurs: Mw. drs. G. Collin, mw. dr. N. E. M. van Haren, dr. H. G. Schnack, mw. prof. dr. H. E. Hulshoff Pol, mw. dr. W. Cahn, prof. dr. E. M. Derks

Gepubliceerd in: Neuropraxis | Uitgave 4/2012

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Samenvatting

Schizofrenie is een progressieve hersenziekte: in de loop van de ziekte is er een voortschrijdend verlies van hersenweefsel. Er is echter aanzienlijke variatie binnen patiënten wat betreft de mate van progressie. Schizofreniepatiënten verschillen onderling eveneens sterk qua symptomatologie. Het is vooralsnog onbekend of die heterogeniteit op klinisch en biologisch vlak aan elkaar gerelateerd zijn. Als er een relatie bestaat, zou dit impliceren dat er mogelijk afzonderlijke neuropathologische mechanismen ten grondslag liggen aan verschillende klinische aspecten van schizofrenie. Onderzoek naar deze relatie zou de detectie van uiteenlopende neuropathologische en genetische factoren in schizofrenie kunnen faciliteren.
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Metagegevens
Titel
Symptoomdimensiescores zijn geassocieerd met progressieve hersenvolumeveranderingen bij schizofrenie
Auteurs
Mw. drs. G. Collin
mw. dr. N. E. M. van Haren
dr. H. G. Schnack
mw. prof. dr. H. E. Hulshoff Pol
mw. dr. W. Cahn
prof. dr. E. M. Derks
Publicatiedatum
01-09-2012
Uitgeverij
Bohn Stafleu van Loghum
Gepubliceerd in
Neuropraxis / Uitgave 4/2012
Print ISSN: 1387-5817
Elektronisch ISSN: 1876-5785
DOI
https://doi.org/10.1007/s12474-012-0021-5

Andere artikelen Uitgave 4/2012

Neuropraxis 4/2012 Naar de uitgave

EditorialNotes

woorden vooraf

OriginalPaper

signalement