Skip to main content
Top
Gepubliceerd in:

06-01-2022

Socio-behavioral factors related to PrEP non-adherence among gay male PrEP users living in California and New York: A behavioral theory informed approach

Auteurs: Minhao Dai, Christopher Calabrese

Gepubliceerd in: Journal of Behavioral Medicine | Uitgave 2/2022

Log in om toegang te krijgen
share
DELEN

Deel dit onderdeel of sectie (kopieer de link)

  • Optie A:
    Klik op de rechtermuisknop op de link en selecteer de optie “linkadres kopiëren”
  • Optie B:
    Deel de link per e-mail

Abstract

One effective preventative measure to reduce the number of new HIV infections is through the uptake of daily oral HIV pre-exposure prophylaxis (PrEP). Although previous clinical trials have proven the effectiveness of on-demand PrEP uptake, daily PrEP uptake is the most popular prevention method among PrEP users and is still recommended by most healthcare professionals and organizations. Informed by the integrative model of behavioral prediction, the current study examined the socio-behavioral factors associated with PrEP non-adherence. The present study conducted a cross-sectional survey of 210 gay male daily PrEP users living in California and New York. The results showed more than two-thirds of the sample indicated that they had skipped taking PrEP within the last 30 days, averaging around four to five missed doses. General attitudes toward desirable and undesirable outcomes, perceived behavioral control, and social-level barriers were associated with daily PrEP uptake non-adherence. The findings highlight providers’ role in PrEP adherence and the importance of habit-forming, which can be enhanced by cost-effective strategies and technological innovations.
Literatuur
go back to reference Baxi, S. M., Liu, A., Bacchetti, P., Mutua, G., Sanders, E. J., Kibengo, F. M., Haberer, J. E., Rooney, J., Hendrix, C. W., Anderson, P. L., Huang, Y., Priddy, F., & Gandhi, M. (2015). Comparing the novel method of assessing PrEP adherence/exposure using hair samples to other pharmacologic and traditional measures. JAIDS Journal of Acquired Immune Deficiency Syndromes, 68(1), 13–20. https://doi.org/10.1097/QAI.0000000000000386CrossRefPubMed Baxi, S. M., Liu, A., Bacchetti, P., Mutua, G., Sanders, E. J., Kibengo, F. M., Haberer, J. E., Rooney, J., Hendrix, C. W., Anderson, P. L., Huang, Y., Priddy, F., & Gandhi, M. (2015). Comparing the novel method of assessing PrEP adherence/exposure using hair samples to other pharmacologic and traditional measures. JAIDS Journal of Acquired Immune Deficiency Syndromes, 68(1), 13–20. https://​doi.​org/​10.​1097/​QAI.​0000000000000386​CrossRefPubMed
go back to reference Holloway, I., Dougherty, R., Gildner, J., Beougher, S. C., Pulsipher, C., Montoya, J. A., Plant, A., & Leibowitz, A. (2017). PrEP uptake, adherence, and discontinuation among California YMSM using geosocial networking applications. Journal of Acquired Immune Deficiency Syndromes (1999), 74(1), 15–20. https://doi.org/10.1097/QAI.0000000000001164CrossRef Holloway, I., Dougherty, R., Gildner, J., Beougher, S. C., Pulsipher, C., Montoya, J. A., Plant, A., & Leibowitz, A. (2017). PrEP uptake, adherence, and discontinuation among California YMSM using geosocial networking applications. Journal of Acquired Immune Deficiency Syndromes (1999), 74(1), 15–20. https://​doi.​org/​10.​1097/​QAI.​0000000000001164​CrossRef
go back to reference Liu, A. Y., Hessol, N. A., Vittinghoff, E., Amico, K. R., Kroboth, E., Fuchs, J., Irvin, R., Sineath, R. C., Sanchez, T., Sullivan, P. S., & Buchbinder, S. P. (2014). Medication adherence among men who have sex with men at risk for HIV infection in the United States: Implications for pre-exposure prophylaxis implementation. AIDS Patient Care and STDs, 28(12), 622–627. https://doi.org/10.1089/apc.2014.0195CrossRefPubMedPubMedCentral Liu, A. Y., Hessol, N. A., Vittinghoff, E., Amico, K. R., Kroboth, E., Fuchs, J., Irvin, R., Sineath, R. C., Sanchez, T., Sullivan, P. S., & Buchbinder, S. P. (2014). Medication adherence among men who have sex with men at risk for HIV infection in the United States: Implications for pre-exposure prophylaxis implementation. AIDS Patient Care and STDs, 28(12), 622–627. https://​doi.​org/​10.​1089/​apc.​2014.​0195CrossRefPubMedPubMedCentral
go back to reference Molina, J. M., Capitant, C., Spire, B., Pialoux, G., Cotte, L., Charreau, I., Tremblay, C., Le Gall, J.-M., Cua, E., Pasquet, A., Raffi, F., Pintado, C., Chidiac, C., Chas, J., Charbonneau, P., Delaugerre, C., Suzan-Monti, M., Loze, B., Fonsart, J., … Delfraissy, J. F. (2015). On-demand preexposure prophylaxis in men at high risk for HIV-1 infection. New England Journal of Medicine, 373(23), 2237–2246. https://doi.org/10.1056/NEJMoa1506273CrossRef Molina, J. M., Capitant, C., Spire, B., Pialoux, G., Cotte, L., Charreau, I., Tremblay, C., Le Gall, J.-M., Cua, E., Pasquet, A., Raffi, F., Pintado, C., Chidiac, C., Chas, J., Charbonneau, P., Delaugerre, C., Suzan-Monti, M., Loze, B., Fonsart, J., … Delfraissy, J. F. (2015). On-demand preexposure prophylaxis in men at high risk for HIV-1 infection. New England Journal of Medicine, 373(23), 2237–2246. https://​doi.​org/​10.​1056/​NEJMoa1506273CrossRef
go back to reference Molina, J.-M., Charreau, I., Spire, B., Cotte, L., Chas, J., Capitant, C., Tremblay, C., Rojas-Castro, D., Cua, E., Pasquet, A., Bernaud, C., Pintado, C., Delaugerre, C., Sagaon-Teyssier, L., Mestre, S. L., Chidiac, C., Pialoux, G., Ponscarme, D., Fonsart, J., … ANRS IPERGAY Study Group. (2017). Efficacy, safety, and effect on sexual behaviour of on-demand pre-exposure prophylaxis for HIV in men who have sex with men: An observational cohort study. The Lancet. HIV, 4(9), e402–e410. https://doi.org/10.1016/S2352-3018(17)30089-9 Molina, J.-M., Charreau, I., Spire, B., Cotte, L., Chas, J., Capitant, C., Tremblay, C., Rojas-Castro, D., Cua, E., Pasquet, A., Bernaud, C., Pintado, C., Delaugerre, C., Sagaon-Teyssier, L., Mestre, S. L., Chidiac, C., Pialoux, G., Ponscarme, D., Fonsart, J., … ANRS IPERGAY Study Group. (2017). Efficacy, safety, and effect on sexual behaviour of on-demand pre-exposure prophylaxis for HIV in men who have sex with men: An observational cohort study. The Lancet. HIV, 4(9), e402–e410. https://​doi.​org/​10.​1016/​S2352-3018(17)30089-9
Metagegevens
Titel
Socio-behavioral factors related to PrEP non-adherence among gay male PrEP users living in California and New York: A behavioral theory informed approach
Auteurs
Minhao Dai
Christopher Calabrese
Publicatiedatum
06-01-2022
Uitgeverij
Springer US
Gepubliceerd in
Journal of Behavioral Medicine / Uitgave 2/2022
Print ISSN: 0160-7715
Elektronisch ISSN: 1573-3521
DOI
https://doi.org/10.1007/s10865-021-00275-1