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13-01-2022

Perceived discrimination, adherence to antiretroviral therapy, and HIV care engagement among HIV-positive black adults: the mediating role of medical mistrust

Auteurs: Lu Dong, Laura M. Bogart, Matt G. Mutchler, Sean J. Lawrence, David J. Klein, Mahlet Gizaw, Glenn J. Wagner

Gepubliceerd in: Journal of Behavioral Medicine | Uitgave 2/2022

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Abstract

Perceived discrimination and medical mistrust are contributors to HIV inequities. The current study examined whether medical mistrust mediated the associations between perceived discrimination and adherence to antiretroviral therapy (ART) as well as care engagement in a sample of 304 Black adults living with HIV. Perceived discrimination and medical mistrust were measured using validated scales; ART adherence was electronically monitored for a month; care engagement was determined by medical record data. Results support significant total indirect effects from perceived discrimination (due to HIV-serostatus, race, sexual orientation) to ART adherence through three types of medical mistrust (towards healthcare organizations, one’s physician, and HIV-specific mistrust). The total indirect effects were also significant for care engagement and were largely driven by mistrust towards one’s own physician. Findings suggest interventions at the provider or healthcare organization levels should address medical mistrust to improve the health and well-being of Black Americans living with HIV.
Literatuur
go back to reference Bangsberg, D. R., Hecht, F. M., Charlebois, E. D., Chesney, M., & Moss, A. (2001). Comparing objective measures of adherence to HIV antiretroviral therapy: Electronic medication monitors and unannounced pill counts. AIDS and Behavior, 5(3), 275–281.CrossRef Bangsberg, D. R., Hecht, F. M., Charlebois, E. D., Chesney, M., & Moss, A. (2001). Comparing objective measures of adherence to HIV antiretroviral therapy: Electronic medication monitors and unannounced pill counts. AIDS and Behavior, 5(3), 275–281.CrossRef
go back to reference Bogart LM, Wagner G, Galvan FH, Banks D (2010) Conspiracy beliefs about HIV are related to antiretroviral treatment nonadherence among African American men with HIV. Journal of Acquired Immune Deficiency Syndromes. 53(5), 648. Bogart LM, Wagner G, Galvan FH, Banks D (2010) Conspiracy beliefs about HIV are related to antiretroviral treatment nonadherence among African American men with HIV. Journal of Acquired Immune Deficiency Syndromes. 53(5), 648.
go back to reference Bogart, L. M., Landrine, H., Galvan, F. H., Wagner, G. J., & Klein, D. J. (2013). Perceived discrimination and physical health among HIV-positive Black and Latino men who have sex with men. AIDS Behav,, 17(4), 1431–1441. Retrieved from https://link.springer.com/content/pdf/https://doi.org/10.1007/s10461-012-0397-5.pdf Bogart, L. M., Landrine, H., Galvan, F. H., Wagner, G. J., & Klein, D. J. (2013). Perceived discrimination and physical health among HIV-positive Black and Latino men who have sex with men. AIDS Behav,, 17(4), 1431–1441. Retrieved from https://​link.​springer.​com/​content/​pdf/​https://​doi.​org/​10.​1007/​s10461-012-0397-5.​pdf
go back to reference Bogart, L. M., Dong, L., Gandhi, P., Ryan, S., Smith, T. L., Klein, D. J., . . . Ojikutu, B. O. (2021). What Contributes to COVID-19 Vaccine Hesitancy in Black Communities, and How Can It Be Addressed? : RAND Corporation. Bogart, L. M., Dong, L., Gandhi, P., Ryan, S., Smith, T. L., Klein, D. J., . . . Ojikutu, B. O. (2021). What Contributes to COVID-19 Vaccine Hesitancy in Black Communities, and How Can It Be Addressed? : RAND Corporation.
go back to reference Bogart, L. M., Mutchler, M. G., McDavitt, B., Klein, D. J., Cunningham, W. E., Goggin, K. J., & Wagner, G. J. (2017). A randomized controlled trial of rise, a community-based culturally congruent adherence intervention for black Americans living with HIV. Annals of Behavioral Medicine, 51(6), 868–878. https://doi.org/10.1007/s12160-017-9910-4CrossRefPubMed Bogart, L. M., Mutchler, M. G., McDavitt, B., Klein, D. J., Cunningham, W. E., Goggin, K. J., & Wagner, G. J. (2017). A randomized controlled trial of rise, a community-based culturally congruent adherence intervention for black Americans living with HIV. Annals of Behavioral Medicine, 51(6), 868–878. https://​doi.​org/​10.​1007/​s12160-017-9910-4CrossRefPubMed
go back to reference Bogart, L. M., Takada, S., & Cunningham, W. E. (2019). Medical Mistrust, Discrimination, and the Domestic HIV Epidemic. In B. O. Ojikutu & V. E. Stone (Eds.), HIV/AIDS in US Communities of Color. Springer. Bogart, L. M., Takada, S., & Cunningham, W. E. (2019). Medical Mistrust, Discrimination, and the Domestic HIV Epidemic. In B. O. Ojikutu & V. E. Stone (Eds.), HIV/AIDS in US Communities of Color. Springer.
go back to reference Bogart, L. M., Takada, S., & Cunningham, W. E. (2021b). Medical Mistrust, Discrimination, and the Domestic HIV Epidemic. In B. O. Ojikutu & V. E. Stone (Eds.), HIV in US Communities of Color (pp. 207–231). Springer International Publishing.CrossRef Bogart, L. M., Takada, S., & Cunningham, W. E. (2021b). Medical Mistrust, Discrimination, and the Domestic HIV Epidemic. In B. O. Ojikutu & V. E. Stone (Eds.), HIV in US Communities of Color (pp. 207–231). Springer International Publishing.CrossRef
go back to reference Bogart, L. M., & Thorburn, S. (2005). Are HIV/AIDS conspiracy beliefs a barrier to HIV prevention among African Americans? JAIDS Journal of Acquired Immune Deficiency Syndromes, 38(2), 213–218.CrossRef Bogart, L. M., & Thorburn, S. (2005). Are HIV/AIDS conspiracy beliefs a barrier to HIV prevention among African Americans? JAIDS Journal of Acquired Immune Deficiency Syndromes, 38(2), 213–218.CrossRef
go back to reference Braksmajer, A., Simmons, J., Aidala, A., & McMahon, J. M. (2018). Effects of discrimination on HIV-related symptoms in heterosexual men of color. American Journal of Men’s Health, 12(6), 1855–1863.CrossRef Braksmajer, A., Simmons, J., Aidala, A., & McMahon, J. M. (2018). Effects of discrimination on HIV-related symptoms in heterosexual men of color. American Journal of Men’s Health, 12(6), 1855–1863.CrossRef
go back to reference Copyright 2002 by the National Academy of Sciences. All rights reserved. Copyright 2002 by the National Academy of Sciences. All rights reserved.
go back to reference Earnshaw, V. A., Bogart, L. M., Dovidio, J. F., & Williams, D. R. (2015). Stigma and racial/ethnic HIV disparities: moving toward resilience. Earnshaw, V. A., Bogart, L. M., Dovidio, J. F., & Williams, D. R. (2015). Stigma and racial/ethnic HIV disparities: moving toward resilience.
go back to reference Hausmann, L. R., Kwoh, C. K., Hannon, M. J., & Ibrahim, S. A. (2013). Perceived racial discrimination in health care and race differences in physician trust. Race and Social Problems, 5(2), 113–120.CrossRef Hausmann, L. R., Kwoh, C. K., Hannon, M. J., & Ibrahim, S. A. (2013). Perceived racial discrimination in health care and race differences in physician trust. Race and Social Problems, 5(2), 113–120.CrossRef
go back to reference Hayes, A. F. (2017). Introduction to mediation, moderation, and conditional process analysis: A regression-based approach: Guilford publications. Hayes, A. F. (2017). Introduction to mediation, moderation, and conditional process analysis: A regression-based approach: Guilford publications.
go back to reference Institute of Medicine Committee on Understanding and Eliminating Racial and Ethnic Disparities in Health Care. (2003). Unequal treatment: confronting racial and ethnic disparities in health care. Washington (DC): National Academies Press (US). Institute of Medicine Committee on Understanding and Eliminating Racial and Ethnic Disparities in Health Care. (2003). Unequal treatment: confronting racial and ethnic disparities in health care. Washington (DC): National Academies Press (US).
go back to reference Institute of Medicine Committee on, U., Eliminating, R., & Ethnic Disparities in Health, C. (2003). In B. D. Smedley, A. Y. Stith, & A. R. Nelson (Eds.), Unequal Treatment: Confronting Racial and Ethnic Disparities in Health Care. Washington (DC): National Academies Press (US) Institute of Medicine Committee on, U., Eliminating, R., & Ethnic Disparities in Health, C. (2003). In B. D. Smedley, A. Y. Stith, & A. R. Nelson (Eds.), Unequal Treatment: Confronting Racial and Ethnic Disparities in Health Care. Washington (DC): National Academies Press (US)
go back to reference Kenny, D. A., & Judd, C. M. (2014). Power anomalies in testing mediation. Psychological Science, 25(2), 334–339.CrossRef Kenny, D. A., & Judd, C. M. (2014). Power anomalies in testing mediation. Psychological Science, 25(2), 334–339.CrossRef
go back to reference LaVeist, T. A., Isaac, L. A., & Williams, K. P. (2009). Mistrust of health care organizations is associated with underutilization of health services. Health Services Research, 44(6), 2093–2105.CrossRef LaVeist, T. A., Isaac, L. A., & Williams, K. P. (2009). Mistrust of health care organizations is associated with underutilization of health services. Health Services Research, 44(6), 2093–2105.CrossRef
go back to reference Lyons, S. J., Dailey, A. F., Yu, C., & Johnson, A. S. (2021). Care Outcomes Among Black or African American Persons with Diagnosed HIV in Rural, Urban, and Metropolitan Statistical Areas - 42 U.S. Jurisdictions, 2018. MMWR Morb Mortal Wkly Rep, 70(7), 229–235. doi:https://doi.org/10.15585/mmwr.mm7007a1 Lyons, S. J., Dailey, A. F., Yu, C., & Johnson, A. S. (2021). Care Outcomes Among Black or African American Persons with Diagnosed HIV in Rural, Urban, and Metropolitan Statistical Areas - 42 U.S. Jurisdictions, 2018. MMWR Morb Mortal Wkly Rep, 70(7), 229–235. doi:https://​doi.​org/​10.​15585/​mmwr.​mm7007a1
go back to reference Muthén, L. K., & Muthén, B. O. (2017). Mplus User’s Guide. 8th Ed. . Retrieved from Los Angeles, CA Muthén, L. K., & Muthén, B. O. (2017). Mplus User’s Guide. 8th Ed. . Retrieved from Los Angeles, CA
go back to reference Ren, X. S., Amick, B. C., & Williams, D. R. (1999). Racial/ethnic disparities in health: The interplay between discrimination and socioeconomic status. Ethnicity & Disease, 9(2), 151–165. Ren, X. S., Amick, B. C., & Williams, D. R. (1999). Racial/ethnic disparities in health: The interplay between discrimination and socioeconomic status. Ethnicity & Disease, 9(2), 151–165.
go back to reference Rintamaki, L. S., Davis, T. C., Skripkauskas, S., Bennett, C. L., & Wolf, M. S. (2006). Social stigma concerns and HIV medication adherence. AIDS Patient Care & STDs, 20(5), 359–368.CrossRef Rintamaki, L. S., Davis, T. C., Skripkauskas, S., Bennett, C. L., & Wolf, M. S. (2006). Social stigma concerns and HIV medication adherence. AIDS Patient Care & STDs, 20(5), 359–368.CrossRef
go back to reference Rolfe, A., Cash‐Gibson, L., Car, J., Sheikh, A., & McKinstry, B. (2014). Interventions for improving patients' trust in doctors and groups of doctors. Cochrane Database Syst Rev,(3), CD004134. Rolfe, A., Cash‐Gibson, L., Car, J., Sheikh, A., & McKinstry, B. (2014). Interventions for improving patients' trust in doctors and groups of doctors. Cochrane Database Syst Rev,(3), CD004134.
go back to reference Rumptz, M. H., Tobias, C., Rajabiun, S., Bradford, J., Cabral, H., Young, R., & Cunningham, W. E. (2007). Factors associated with engaging socially marginalized HIV-positive persons in primary care. AIDS Patient Care and STDs, 21(S1), S-30-S-39. Rumptz, M. H., Tobias, C., Rajabiun, S., Bradford, J., Cabral, H., Young, R., & Cunningham, W. E. (2007). Factors associated with engaging socially marginalized HIV-positive persons in primary care. AIDS Patient Care and STDs, 21(S1), S-30-S-39.
go back to reference Thom, D. H., Ribisl, K. M., Stewart, A. L., Luke, D. A., & Physicians, T. S. T. S. (1999). Further validation and reliability testing of the Trust in Physician Scale. Medical care, 510–517. Thom, D. H., Ribisl, K. M., Stewart, A. L., Luke, D. A., & Physicians, T. S. T. S. (1999). Further validation and reliability testing of the Trust in Physician Scale. Medical care, 510–517.
go back to reference Thom, D. H., Tirado, M. D., Woon, T. L., & McBride, M. R. (2006). Development and evaluation of a cultural competency training curriculum. BMC Medical Education, 6, 38.CrossRef Thom, D. H., Tirado, M. D., Woon, T. L., & McBride, M. R. (2006). Development and evaluation of a cultural competency training curriculum. BMC Medical Education, 6, 38.CrossRef
go back to reference Thomas, K. S., Bardwell, W. A., Ancoli-Israel, S., & Dimsdale, J. E. (2006). The toll of ethnic discrimination on sleep architecture and fatigue. Health Psychology, 25(5), 635.CrossRef Thomas, K. S., Bardwell, W. A., Ancoli-Israel, S., & Dimsdale, J. E. (2006). The toll of ethnic discrimination on sleep architecture and fatigue. Health Psychology, 25(5), 635.CrossRef
go back to reference Thrasher, A. D., Earp, J. A. L., Golin, C. E., & Zimmer, C. R. (2008). Discrimination, distrust, and racial/ethnic disparities in antiretroviral therapy adherence among a national sample of HIV-infected patients. JAIDS Journal of Acquired Immune Deficiency Syndromes, 49(1), 84–93.CrossRef Thrasher, A. D., Earp, J. A. L., Golin, C. E., & Zimmer, C. R. (2008). Discrimination, distrust, and racial/ethnic disparities in antiretroviral therapy adherence among a national sample of HIV-infected patients. JAIDS Journal of Acquired Immune Deficiency Syndromes, 49(1), 84–93.CrossRef
go back to reference Tulsky, J. A., Arnold, R. M., Alexander, S. C., Olsen, M. K., Jeffreys, A. S., Rodriguez, K. L., & Pollak, K. I. (2011). Enhancing communication between oncologists and patients with a computer-based training program: A randomized trial. Annals of Internal Medicine, 155(9), 593–601.CrossRef Tulsky, J. A., Arnold, R. M., Alexander, S. C., Olsen, M. K., Jeffreys, A. S., Rodriguez, K. L., & Pollak, K. I. (2011). Enhancing communication between oncologists and patients with a computer-based training program: A randomized trial. Annals of Internal Medicine, 155(9), 593–601.CrossRef
go back to reference Wagner, G. J., Bogart, L. M., Mutchler, M. G., McDavitt, B., Mutepfa, K. D., & Risley, B. (2016). Increasing antiretroviral adherence for HIV-positive African Americans (project Rise): A treatment education intervention protocol. JMIR Res Protoc, 5(1), e45.CrossRef Wagner, G. J., Bogart, L. M., Mutchler, M. G., McDavitt, B., Mutepfa, K. D., & Risley, B. (2016). Increasing antiretroviral adherence for HIV-positive African Americans (project Rise): A treatment education intervention protocol. JMIR Res Protoc, 5(1), e45.CrossRef
go back to reference Williamson, L. D., Smith, M. A., & Bigman, C. A. (2019). Does discrimination breed mistrust? Examining the role of mediated and non-mediated discrimination experiences in medical mistrust. Journal of Health Communication, 24(10), 791–799. Retrieved from https://www.tandfonline.com/doi/pdf/https://doi.org/10.1080/10810730.2019.1669742?needAccess=true Williamson, L. D., Smith, M. A., & Bigman, C. A. (2019). Does discrimination breed mistrust? Examining the role of mediated and non-mediated discrimination experiences in medical mistrust. Journal of Health Communication, 24(10), 791–799. Retrieved from https://​www.​tandfonline.​com/​doi/​pdf/​https://​doi.​org/​10.​1080/​10810730.​2019.​1669742?​needAccess=​true
Metagegevens
Titel
Perceived discrimination, adherence to antiretroviral therapy, and HIV care engagement among HIV-positive black adults: the mediating role of medical mistrust
Auteurs
Lu Dong
Laura M. Bogart
Matt G. Mutchler
Sean J. Lawrence
David J. Klein
Mahlet Gizaw
Glenn J. Wagner
Publicatiedatum
13-01-2022
Uitgeverij
Springer US
Gepubliceerd in
Journal of Behavioral Medicine / Uitgave 2/2022
Print ISSN: 0160-7715
Elektronisch ISSN: 1573-3521
DOI
https://doi.org/10.1007/s10865-021-00277-z

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