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01-06-2012 | Original Paper | Uitgave 6/2012

Predictors and Moderators of Parent Training Efficacy in a Sample of Children with Autism Spectrum Disorders and Serious Behavioral Problems

Tijdschrift:: Journal of Autism and Developmental Disorders > Uitgave 6/2012

Auteurs:: Cristan Farmer, Luc Lecavalier, Sunkyung Yu, L. Eugene Arnold, Christopher J. McDougle, Lawrence Scahill, Benjamin Handen, Cynthia R. Johnson, Kimberly A. Stigler, Karen Bearss, Naomi B. Swiezy, Michael G. Aman

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Clinical trial registration information RUPP PI PDD: Drug and Behavioral Therapy for Children with Pervasive Developmental Disorders. URL: http://www.clinicaltrials.gov. Unique identifier: NCT00080145.

Abstract

The Research Units on Pediatric Psychopharmacology—Autism Network reported additional benefit when adding parent training (PT) to antipsychotic medication in children with autism spectrum disorders and serious behavior problems. The intent-to-treat analyses were rerun with putative predictors and moderators. The Home Situations Questionnaire (HSQ) and the Hyperactivity/Noncompliance subscale of the Aberrant Behavior Checklist were used as outcome measures. Candidate predictors and moderators included 21 demographics and baseline measures of behavior. Higher baseline HSQ scores predicted greater improvement on the HSQ regardless of treatment assignment, but no other predictors of outcome were observed. None of the variables measured in this study moderated response to PT. Antipsychotic medication plus PT appears to be equally effective for children with a wide range of demographic and behavioral characteristics.

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Titel: Predictors and Moderators of Parent Training Efficacy in a Sample of Children with Autism Spectrum Disorders and Serious Behavioral Problems
Auteurs:: Cristan Farmer
Luc Lecavalier
Sunkyung Yu
L. Eugene Arnold
Christopher J. McDougle
Lawrence Scahill
Benjamin Handen
Cynthia R. Johnson
Kimberly A. Stigler
Karen Bearss
Naomi B. Swiezy
Michael G. Aman
Publicatiedatum: 01-06-2012
DOI: https://doi.org/10.1007/s10803-011-1338-2
Uitgeverij: Springer US
Tijdschrift: Journal of Autism and Developmental Disorders
Uitgave 6/2012
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432

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