Swipe om te navigeren naar een ander artikel
Beliefs about medication necessity and concerns predict treatment adherence in people with a wide-array of medical conditions, including HIV infection. However, medication beliefs have not been examined in people dually treated with psychotropic medications and antiretroviral therapy. In the current study, we used a prospective design to investigate the factors associated with adherence to psychotropic medications and antiretrovirals among 123 dually treated persons living with HIV. We used unannounced phone-based pill counts to monitor adherence to psychiatric and antiretroviral medications over a 6-week period. Hierarchical regression models included demographic, health and psychosocial characteristics as predictors of adherence followed by medication necessity and concerns beliefs. Results showed that medication necessity beliefs predicted both antiretroviral and psychiatric medication adherence over and above established predictors of adherence. Medication concerns also predicted psychotropic adherence, but not antiretroviral adherence. These models accounted for 31 and 22 % of the variance in antiretroviral and psychotropic adherence, respectively. Findings suggest that the necessity-concerns medication beliefs framework has utility in understanding adherence to multiple medications and addressing these beliefs should be integrated into adherence interventions.
Log in om toegang te krijgen
Met onderstaand(e) abonnement(en) heeft u direct toegang:
Bangsberg, D. R., Hecht, F. M., Charlebois, E. D., Chesney, M., & Moss, A. (2001). Comparing objective measures of adherence to HIV antiretroviral therapy: Electronic medication monitors and unannounced pill counts. AIDS and Behavior, 5, 275–281. CrossRef
Belenky, N. M., Cole, S. R., Pence, B. W., Itemba, D., Maro, V., & Whetten, K. (2014). Depressive symptoms, HIV medication adherence, and HIV clinical outcomes in Tanzania: a prospective, observational study. PLoS ONE, 9(5), e95469.
Brock, D., Sarason, I., Sarason, B., & Pierce, G. (1996). Simultaneous assessment of perceived global and relationship-specific support. Journal of Social and Personal Relationships, 13, 143–152. CrossRef
Chitsaz, E., Meyer, J. P., Krishnan, A., Springer, S. A., Marcus, R., Zaller, N., et al. (2013). Contribution of substance use disorders on HIV treatment outcomes and antiretroviral medication adherence among HIV-infected persons entering jail. AIDS and Behavior, 17(Suppl 2), S118–S127. PubMedCrossRef
Cruess, D. G., Kalichman, S. C., Amaral, C., Swetzes, C., Cherry, C., & Kalichman, M. O. (2012). Benefits of adherence to psychotropic medications on depressive symptoms and antiretroviral medication adherence among men and women living with HIV/AIDS. Annals of Behavioral Medicine, 43(2), 189–197. PubMedCentralPubMedCrossRef
Horne, R. (2011). Adherence to asthma medication: A question of ability? Primary Care in Respiration Journal, 20(2), 118–119. CrossRef
Horne, R., Chapman, S. C., Parham, R., Freemantle, N., Forbes, A., & Cooper, V. (2013). Understanding patients’ adherence-related beliefs about medicines prescribed for long-term conditions: A meta-analytic review of the Necessity-Concerns Framework. PLoS ONE, 8(12), e80633. PubMedCentralPubMedCrossRef
Horne, R., Cooper, V., Gellaitry, G., Date, H. L., & Fisher, M. (2007). Patients’ perceptions of highly active antiretroviral therapy in relation to treatment uptake and adherence: The utility of the necessity-concerns framework. Journal of Acquired Immune Deficiency Syndromes, 45(3), 334–341. PubMed
Horne, R., Parham, R., Driscoll, R., & Robinson, A. (2009). Patients’ attitudes to medicines and adherence to maintenance treatment in inflammatory bowel disease. Inflammatory Bowel Disorders, 15(6), 837–844. CrossRef
Jonsdottir, H., Friis, S., Horne, R., Pettersen, K. I., Reikvam, A., & Andreassen, O. A. (2009). Beliefs about medications: Measurement and relationship to adherence in patients with severe mental disorders. Acta Psychiatrica Scandanavia, 119(1), 78–84. CrossRef
Lee, S., Rothbard, A. B., Noll, E., & Blank, M. B. (2011). Use of HIV and psychotropic medications among persons with serious mental illness and HIV/AIDS. Administrative Policy Mental Health, 38(5), 335–344. CrossRef
Mayston, R., Kinyanda, E., Chishinga, N., Prince, M., & Patel, V. (2012). Mental disorder and the outcome of HIV/AIDS in low-income and middle-income countries: A systematic review. AIDS, 26 Suppl 2, S117-135.
Newville, H., Berg, K. M., & Gonzalez, J. S. (2014). The interaction of active substance use, depression, and antiretroviral adherence in methadone maintenance. International Journal of Behavioral Medicine.
Saunders, J. B., Aasland, O. G., Babor, T. F., DeLaFuente, J. R., & Grant, M. (1993). Development of the alcohol use disorders identification test (AUDIT): WHO collaborative project on early detection of persons with harmful alcohol consumption II. Addictions, 88(6), 791–804. CrossRef
Sublette, V. A., Douglas, M. W., McCaffery, K., George, J., & Perry, K. N. (2013). Psychological, lifestyle and social predictors of hepatitis C treatment response: A systematic review. Liver Intervention, 33(6), 894–903. CrossRef
- Medication adherence in people dually treated for HIV infection and mental health conditions: test of the medications beliefs framework
Seth C. Kalichman
Moira O. Kalichman
- Springer US