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Gepubliceerd in:

01-08-2015

Medication adherence in people dually treated for HIV infection and mental health conditions: test of the medications beliefs framework

Auteurs: Seth C. Kalichman, Jennifer Pellowski, Christopher Kegler, Chauncey Cherry, Moira O. Kalichman

Gepubliceerd in: Journal of Behavioral Medicine | Uitgave 4/2015

Abstract

Beliefs about medication necessity and concerns predict treatment adherence in people with a wide-array of medical conditions, including HIV infection. However, medication beliefs have not been examined in people dually treated with psychotropic medications and antiretroviral therapy. In the current study, we used a prospective design to investigate the factors associated with adherence to psychotropic medications and antiretrovirals among 123 dually treated persons living with HIV. We used unannounced phone-based pill counts to monitor adherence to psychiatric and antiretroviral medications over a 6-week period. Hierarchical regression models included demographic, health and psychosocial characteristics as predictors of adherence followed by medication necessity and concerns beliefs. Results showed that medication necessity beliefs predicted both antiretroviral and psychiatric medication adherence over and above established predictors of adherence. Medication concerns also predicted psychotropic adherence, but not antiretroviral adherence. These models accounted for 31 and 22 % of the variance in antiretroviral and psychotropic adherence, respectively. Findings suggest that the necessity-concerns medication beliefs framework has utility in understanding adherence to multiple medications and addressing these beliefs should be integrated into adherence interventions.

vorige artikel Illness perceptions and coping strategies among individuals diagnosed with HIV

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Angelino, A. F., & Treisman, G. J. (2008). Issues in co-morbid severe mental illnesses in HIV infected individuals. International Review of Psychiatry, 20(1), 95–101.PubMedCrossRef

Bangsberg, D., & Deeks, S. G. (2002). Is average adherence to HIV antiretroviral therapy enough? Journal of General Internal Medicine, 17(10), 812–813.PubMedCentralPubMedCrossRef

Bangsberg, D. R., Hecht, F. M., Charlebois, E. D., Chesney, M., & Moss, A. (2001). Comparing objective measures of adherence to HIV antiretroviral therapy: Electronic medication monitors and unannounced pill counts. AIDS and Behavior, 5, 275–281.CrossRef

Belenky, N. M., Cole, S. R., Pence, B. W., Itemba, D., Maro, V., & Whetten, K. (2014). Depressive symptoms, HIV medication adherence, and HIV clinical outcomes in Tanzania: a prospective, observational study. PLoS ONE, 9(5), e95469.

Brock, D., Sarason, I., Sarason, B., & Pierce, G. (1996). Simultaneous assessment of perceived global and relationship-specific support. Journal of Social and Personal Relationships, 13, 143–152.CrossRef

Carrieri, M. P., Villes, V., Raffi, F., Protpopescu, C., Preau, M., Salmon, D., et al. (2007). Self-reported side-effects of anti-retroviral treatment among IDUs: a 7-year longitudinal study (APROCO-COPILOTE COHORT ANRS CO-8). International Journal of Drug Policy, 18(4), 288–295.PubMedCrossRef

Chapman, S. C., & Horne, R. (2013). Medication nonadherence and psychiatry. Current Opinion in Psychiatry, 26(5), 446–452.PubMedCentralPubMedCrossRef

Chesney, M., Folkman, S., & Chambers, D. (1996). Coping effectiveness training for men living with HIV: Preliminary findings. International Journal of STD and AIDS, 7(Suppl 2), 75–82.PubMedCrossRef

Chitsaz, E., Meyer, J. P., Krishnan, A., Springer, S. A., Marcus, R., Zaller, N., et al. (2013). Contribution of substance use disorders on HIV treatment outcomes and antiretroviral medication adherence among HIV-infected persons entering jail. AIDS and Behavior, 17(Suppl 2), S118–S127.PubMedCrossRef

Cruess, D. G., Kalichman, S. C., Amaral, C., Swetzes, C., Cherry, C., & Kalichman, M. O. (2012). Benefits of adherence to psychotropic medications on depressive symptoms and antiretroviral medication adherence among men and women living with HIV/AIDS. Annals of Behavioral Medicine, 43(2), 189–197.PubMedCentralPubMedCrossRef

De Socio, G. V., Fanelli, L., Longo, A., & Stagni, G. (2004). Adherence to antiretroviral therapy in HIV patients with psychiatric comorbidity. Journal of Acquired Immune Deficiency Syndromes, 36(5), 1109–1110.PubMedCrossRef

Gonzalez, J. S., Penedo, F. J., Llabre, M. M., Duran, R. E., Antoni, M. H., Schneiderman, N., & Horne, R. (2007). Physical symptoms, beliefs about medications, negative mood, and long-term HIV medication adherence. Annals of Behavioral Medicine, 34(1), 46–55.PubMedCrossRef

Gribble, J. N., Miller, H. G., Cooley, P. C., Catania, J. A., Pollack, L., & Turner, C. F. (2000). The impact of T-ACASI interviewing on reported drug use among men who have sex with men. Substance Use and Misuse, 35(6–8), 869–890.PubMedCrossRef

Horne, R. (2011). Adherence to asthma medication: A question of ability? Primary Care in Respiration Journal, 20(2), 118–119.CrossRef

Horne, R., Buick, D., Fisher, M., Leake, H., Cooper, V., & Weinman, J. (2004). Doubts about necessity and concerns about adverse effects: identifying the types of beliefs that are associated with non-adherence to HAART. International Journal of STD and AIDS, 15(1), 38–44.PubMedCrossRef

Horne, R., Chapman, S. C., Parham, R., Freemantle, N., Forbes, A., & Cooper, V. (2013). Understanding patients’ adherence-related beliefs about medicines prescribed for long-term conditions: A meta-analytic review of the Necessity-Concerns Framework. PLoS ONE, 8(12), e80633.PubMedCentralPubMedCrossRef

Horne, R., Cooper, V., Gellaitry, G., Date, H. L., & Fisher, M. (2007). Patients’ perceptions of highly active antiretroviral therapy in relation to treatment uptake and adherence: The utility of the necessity-concerns framework. Journal of Acquired Immune Deficiency Syndromes, 45(3), 334–341.PubMed

Horne, R., Parham, R., Driscoll, R., & Robinson, A. (2009). Patients’ attitudes to medicines and adherence to maintenance treatment in inflammatory bowel disease. Inflammatory Bowel Disorders, 15(6), 837–844.CrossRef

Huang, Y., Wei, X., Wu, T., Chen, R., & Guo, A. (2013). Collaborative care for patients with depression and diabetes mellitus: A systematic review and meta-analysis. BMC Psychiatry, 13, 260.PubMedCentralPubMedCrossRef

Jonsdottir, H., Friis, S., Horne, R., Pettersen, K. I., Reikvam, A., & Andreassen, O. A. (2009). Beliefs about medications: Measurement and relationship to adherence in patients with severe mental disorders. Acta Psychiatrica Scandanavia, 119(1), 78–84.CrossRef

Kalichman, S. C., Amaral, C. M., Cherry, C., Flanagan, J. A., Pope, H., Eaton, L., et al. (2008). Monitoring Antiretroviral adherence by unannounced pill counts conducted by telephone: Reliability and criterion-related validity. HIV Clinical Trials, 9, 298–308.PubMedCentralPubMedCrossRef

Kalichman, S. C., Amaral, C. M., Stearns, H. L., White, D., Flanagan, J. A., Pope, H., & Kalichman, M. O. (2007). Adherence to antiretroviral therapy assessed by unannounced pill counts conducted by telephone. Journal of General Internal Medicine, 22, 1003–1006.PubMedCentralPubMedCrossRef

Kalichman, S., DiMarco, M., Austin, J., Luke, W., & DiFonzo, K. (2003). Stress, social support, and HIV-status disclosure to family and friends among HIV-positive men and women. Journal of Behavioral Medicine, 26(4), 315–332.PubMedCrossRef

Kalichman, S., Rompa, D., & Cage, M. (2000). Reliability and validity of self-reported CD4 lymphocyte count and viral load test results in people living with HIV/AIDS. International Journal of STD AIDS, 11(9), 579–585.PubMedCrossRef

Lee, S., Rothbard, A. B., Noll, E., & Blank, M. B. (2011). Use of HIV and psychotropic medications among persons with serious mental illness and HIV/AIDS. Administrative Policy Mental Health, 38(5), 335–344.CrossRef

Leserman, J. (2008). Role of depression, stress, and trauma in HIV disease progression. Psychosomatic Medicine, 70(5), 539–545.PubMedCrossRef

Leserman, J., Ironson, G., O’Cleirigh, C., Fordiani, J. M., & Balbin, E. (2008). Stressful life events and adherence in HIV. AIDS Patient Care and STDs, 22(5), 403–411.PubMedCentralPubMedCrossRef

Maisto, S. A., Conigliaro, J., McNeil, M., Kraemer, K., & Kelley, M. E. (2000). An empirical investigation of the factor structure of the AUDIT. Psychological Assessment, 12(3), 346–353.PubMedCrossRef

Mayston, R., Kinyanda, E., Chishinga, N., Prince, M., & Patel, V. (2012). Mental disorder and the outcome of HIV/AIDS in low-income and middle-income countries: A systematic review. AIDS, 26 Suppl 2, S117-135.

Morrison-Beedy, D., Carey, M. P., & Tu, X. (2006). Accuracy of audio computer-assisted self-interviewing (ACASI) and self-administered questionnaires for the assessment of sexual behavior. AIDS and Behavior, 10(5), 541–552.PubMedCentralPubMedCrossRef

Nel, A., & Kagee, A. (2011). Common mental health problems and antiretroviral therapy adherence. AIDS Care, 23(11), 1360–1365.PubMedCrossRef

Newville, H., Berg, K. M., & Gonzalez, J. S. (2014). The interaction of active substance use, depression, and antiretroviral adherence in methadone maintenance. International Journal of Behavioral Medicine.

Saunders, J. B., Aasland, O. G., Babor, T. F., DeLaFuente, J. R., & Grant, M. (1993). Development of the alcohol use disorders identification test (AUDIT): WHO collaborative project on early detection of persons with harmful alcohol consumption II. Addictions, 88(6), 791–804.CrossRef

Sikkema, K. J., Watt, M. H., Drabkin, A. S., Meade, C. S., Hansen, N. B., & Pence, B. W. (2010). Mental health treatment to reduce HIV transmission risk behavior: A positive prevention model. AIDS and Behavior, 14(2), 252–262.PubMedCentralPubMedCrossRef

Springer, S. A., Dushaj, A., & Azar, M. M. (2012). The impact of DSM-IV mental disorders on adherence to combination antiretroviral therapy among adult persons living with HIV/AIDS: A systematic review. AIDS and Behavior, 16(8), 2119–2143.PubMedCentralPubMedCrossRef

Sublette, V. A., Douglas, M. W., McCaffery, K., George, J., & Perry, K. N. (2013). Psychological, lifestyle and social predictors of hepatitis C treatment response: A systematic review. Liver Intervention, 33(6), 894–903.CrossRef

Van Dam, N. T., & Earleywine, M. (2011). Validation of the center for epidemiologic studies depression scale-revised (CESD-R): Pragmatic depression assessment in the general population. Psychiatry Research, 186(1), 128–132.PubMedCrossRef

Walkup, J., Blank, M. B., Gonzalez, J. S., Safren, S., Schwartz, R., Brown, L., et al. (2008). The impact of mental health and substance abuse factors on HIV prevention and treatment. Journal of Acquired Immune Deficiency Syndromes, 47(Suppl 1), S15–S19.PubMedCrossRef

Titel: Medication adherence in people dually treated for HIV infection and mental health conditions: test of the medications beliefs framework
Auteurs: Seth C. Kalichman
Jennifer Pellowski
Christopher Kegler
Chauncey Cherry
Moira O. Kalichman
Publicatiedatum: 01-08-2015
Uitgeverij: Springer US
Gepubliceerd in: Journal of Behavioral Medicine / Uitgave 4/2015
Print ISSN: 0160-7715
Elektronisch ISSN: 1573-3521
DOI: https://doi.org/10.1007/s10865-015-9633-6

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