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Gepubliceerd in: Journal of Psychopathology and Behavioral Assessment 3/2023

21-06-2023

Irritability and Suicidality in Clinically Referred Youth: Clarifying the Link by Examining the Roles of Age and Hope

Auteurs: Sakshi Khurana, Melissa A. Wei, Ashley R. Karlovich, Spencer C. Evans

Gepubliceerd in: Journal of Psychopathology and Behavioral Assessment | Uitgave 3/2023

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Abstract

Research has found an association between irritability and suicidal thoughts and behaviors (STB) in children and adolescents, but the overall evidence has been mixed and the nature of this association remains unclear. In this study, we investigated whether the link between irritability and STB might be more pronounced among older youth and those with lower levels of hope. Participants were 142 children and adolescents (ages 6–18) referred for mental health services at a university outpatient clinic. At intake, clinicians administered self-report measures assessing irritability, STB, hope, and depression. Multiple regression models with robust maximum likelihood estimation were used to test irritability’s association with STB, as well as age and hope as moderators. Irritability, hope, and age all showed significant associations with STB. Further, hope and age moderated the associations between irritability and STB; specifically, the link between irritability and STB was evident only at older ages (among adolescents, not children) and only at lower levels of hope. These findings are consistent with the view that hope may be a protective factor, and adolescence a vulnerability factor, in the association between irritability and STB. Results may help explain previous mixed findings on this association while also underscoring the role of irritability as a risk factor. Further research is warranted to better understand irritability and hope as transdiagnostic mechanisms in STB from childhood through adulthood, and through other informants and methods.
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Both models were re-estimated controlling depression, and results changed slightly (see Supplement, Tables S1 and S2). To summarize, depression was a significant predictor of STB (p < .001) in all models and steps. Including depression resulted in a sizable increase in variance accounted for in both Model 1 (from 15–17% without depression to 32–33% with depression) and Model 2 (from 18–23% without depression to 30–33% with depression). The depression-STB link tended to overshadow other terms in these models, attenuating the hope × irritability interaction term to nonsignificance (p = .162) while the age × irritability interaction term remained robust (p = .047). Nonetheless, the overall protective effect of hope and the vulnerability effect of adolescence remained apparent (see Figures S1 and S2).
 
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Metagegevens
Titel
Irritability and Suicidality in Clinically Referred Youth: Clarifying the Link by Examining the Roles of Age and Hope
Auteurs
Sakshi Khurana
Melissa A. Wei
Ashley R. Karlovich
Spencer C. Evans
Publicatiedatum
21-06-2023
Uitgeverij
Springer US
Gepubliceerd in
Journal of Psychopathology and Behavioral Assessment / Uitgave 3/2023
Print ISSN: 0882-2689
Elektronisch ISSN: 1573-3505
DOI
https://doi.org/10.1007/s10862-023-10049-5

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