Swipe om te navigeren naar een ander artikel
To investigate the relation of demographic factors, medication and symptoms to health-related quality of life in patients with inflammatory bowel disease, and to identify patients in need of special support.
A questionnaire packet comprising the Inflammatory Bowel Disease Questionnaire (IBDQ) and the European Federation of Crohn’s and Colitis Associations’ (EFCCA) Survey Questionnaire was sent to 3,852 adult members of the Crohn and Colitis Association of Finland. IBDQ was used for measuring health-related quality of life (HRQoL), and the EFCCA questionnaire gave information about demographics, symptoms and medication.
Altogether 2,386 questionnaires (62%) were available for analysis. Patients reporting symptoms affecting leisure activities or work had significantly lower total IBDQ scores (indicating worse HRQoL) than patients with less disturbing symptoms. Satisfaction with current therapy, female gender and age affected the scores. Subjects who had undergone surgery scored lower than those who had not. Patients currently receiving corticosteroids and newly diagnosed patients had lower scores than other patients.
In everyday practice, paying attention to and reducing patients’ symptoms and their impact on daily life is important when aiming at improving HRQoL. Special attention should be given to patients who have undergone surgery, and to newly diagnosed patients.
Log in om toegang te krijgen
Met onderstaand(e) abonnement(en) heeft u direct toegang:
Wilson, I. B., & Cleary, P. D. (1995). Linking clinical variables with health-related quality of life: A conceptual model of patient outcomes. Journal of American Medical Association,273, 59–65. CrossRef
Palm, Ø., Bernklev, T., Moum, B., et al. (2005). Non-inflammatory joint pain in patients with inflammatory bowel disease is prevalent and has a significant impact on health related quality of life. Journal of Rheumatology,32, 1755–1759. PubMed
Bernklev, T., Jahnsen, J., Henriksen, M., et al. (2006). Relationship between sick leave, unemployment, disability, and health-related quality of life in patients with inflammatory bowel disease. Inflammatory Bowel Disease,12, 402–412. CrossRef
Bernklev, T., Jahnsen, J., Lygren, I., et al. (2005). Health-related quality of life in patients with inflammatory bowel disease measured with the Short Form-36: Psychometric assessments and a comparison with general population norms. Inflammatory Bowel Disease,11, 909–918. CrossRef
Irvine, E. J., Feagan, B., Rochon, J., et al. (1994). Quality of life: A valid and reliable measure of therapeutic efficacy in the treatment of inflammatory bowel disease. Gastroenterology,106, 287–296. PubMed
Casellas, F., Arenas, J. I., Baudet, J. S., et al. (2005). Impairment of health-related quality of life in patients with inflammatory bowel disease: A Spanish multicenter study. Inflammatory Bowel Disease,11, 488–496. CrossRef
Zahn, A., Hinz, U., Karner, M., et al. (2006). Health-related quality of life correlates with clinical and endoscopic activity indexes but not with demographic features in patients with ulcerative colitis. Inflammatory Bowel Disease,12, 1058–1067. CrossRef
Guyatt, G., Mitchell, A., Irvine, E. J., et al. (1989). A new measure of health status for clinical trials in inflammatory bowel disease. Gastroenterology,96, 804–810. PubMed
Bernklev, T., Moum, B., Moum, T., et al. (2002). Quality of life in patients with inflammatory bowel disease: Translation, data quality, scaling assumptions, validity, reliability and sensitivity to change of the Norwegian version of IBDQ. Scandinavian Journal of Gastroenterology,37, 1164–1174. PubMedCrossRef
Ghosh, S., & Mitchell, R. (2007). Impact of inflammatory bowel disease on quality of life: Results of the European Federation of Crohn’s and Ulcerative Colitis Associations (EFCCA) patient survey. Journal of Crohn’s and Colitis,1, 10–20. CrossRef
Han, S. W., McColl, E., Barton, J. R., et al. (2005). Predictors of quality of life in ulcerative colitis: The importance of symptoms and illness representations. Inflammatory Bowel Disease,11, 24–34. CrossRef
Canavan, C., Abrams, K. R., Hawthorne, B., et al. (2006). Long-term prognosis in Crohn’s disease: Factors that affect quality of life. Alimentary Pharmacology & Therapeutics,23, 377–385. CrossRef
Rutgeerts, P., Geboes, K., Vantrappen, G., et al. (1990). Predictability of the postoperative course of Crohn’s disease. Gastroenterology,99, 956–963. PubMed
Michelassi, F., Lee, J., Rubin, M., et al. (2003). Long-term functional results after ileal pouch anal restorative proctocolectomy for ulcerative colitis. A prospective observational study. Annals of Surgery,238, 433–445. PubMed
Otley, A. R., Griffiths, A. M., Hale, S., et al. (2006). Health-related quality of life in the first year after a diagnosis of pediatric inflammatory bowel disease. Inflammatory Bowel Disease,12, 684–691. CrossRef
- Impact of demographic factors, medication and symptoms on disease-specific quality of life in inflammatory bowel disease
Risto P. Roine
Martti A. Färkkilä
Perttu E. T. Arkkila
- Springer Netherlands