Top

Journal of Autism and Developmental Disorders

Gepubliceerd in:

25-06-2022 | Original Paper

Distinct Symptom Network Structure and Shared Central Social Communication Symptomatology in Autism and Schizophrenia: A Bayesian Network Analysis

Auteurs: Gloria T. Han, Dominic A. Trevisan, Jennifer Foss-Feig, Vinod Srihari, James C. McPartland

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 9/2023

Abstract

Autism (ASD) and schizophrenia spectrum disorders (SCZ) are neurodevelopmental conditions with overlapping and interrelated symptoms. A network analysis approach that represents clinical conditions as a set of “nodes” (symptoms) connected by “edges” (relations among symptoms) was used to compare symptom organization in the two conditions. Gaussian graphical models were estimated using Bayesian methods to model separate symptom networks for adults with confirmed ASD or SCZ diagnoses. Though overall symptom organization differed by diagnostic group, both symptom networks demonstrated high centrality of social communication difficulties. Autism-relevant restricted and repetitive behaviors and schizophrenia-related cognitive-perceptual symptoms were uniquely central to the ASD and SCZ networks, respectively. Results offer recommendations to improve differential diagnosis and highlight potential treatment targets in ASD and SCZ.

vorige artikel Are there gender-based variations in the presentation of Autism amongst female and male children?

volgende artikel Layer-Specific Changes in the Prefrontal Glia/Neuron Ratio Characterizes Patches of Gene Expression Disorganization in Children with Autism

Borsboom, D., & Cramer, A. O. (2013). Network analysis: An integrative approach to the structure of psychopathology. Annual Review of Clinical Psychology, 9, 91–121.CrossRefPubMed

Chandrasekhar, T., Copeland, J. N., Spanos, M., & Sikich, L. (2020). Autism, psychosis, or both? Unraveling complex patient presentations. Child and Adolescent Psychiatric Clinics, 29(1), 103–113.CrossRef

Chen, H., Uddin, L. Q., Duan, X., Zheng, J., Long, Z., Zhang, Y., Guo, X., Zhang, Y., Zhao, J., & Chen, H. (2017). Shared atypical default mode and salience network functional connectivity between autism and schizophrenia. Autism Research, 10(11), 1776–1786.CrossRefPubMedPubMedCentral

Chien, Y. L., Wu, C. S., & Tsai, H. J. (2021). The comorbidity of schizophrenia spectrum and mood disorders in autism spectrum disorder. Autism Research, 14(3), 571–581.CrossRefPubMed

Constantino, J. N., & Gruber, C. P. (2012). Social responsiveness scale: SRS-2. Western Psychological Services Torrance.

Couture, S., Penn, D., Losh, M., Adolphs, R., Hurley, R., & Piven, J. (2010). Comparison of social cognitive functioning in schizophrenia and high functioning autism: More convergence than divergence. Psychological Medicine, 40(4), 569–579.CrossRefPubMed

Dawson, G., Carver, L., Meltzoff, A. N., Panagiotides, H., McPartland, J., & Webb, S. J. (2002). Neural correlates of face and object recognition in young children with autism spectrum disorder, developmental delay, and typical development. Child Development, 73(3), 700–717.CrossRefPubMedPubMedCentral

Dawson, G., Webb, S. J., & McPartland, J. (2005). Understanding the nature of face processing impairment in autism: Insights from behavioral and electrophysiological studies. Developmental Neuropsychology, 27(3), 403–424.CrossRefPubMed

De Crescenzo, F., Postorino, V., Siracusano, M., Riccioni, A., Armando, M., Curatolo, P., & Mazzone, L. (2019). Autistic symptoms in schizophrenia spectrum disorders: A systematic review and meta-analysis. Frontiers in Psychiatry, 10, 78.CrossRefPubMedPubMedCentral

Dickinson, D., Bellack, A. S., & Gold, J. M. (2007). Social/communication skills, cognition, and vocational functioning in schizophrenia. Schizophrenia Bulletin, 33(5), 1213–1220.CrossRefPubMed

Eack, S. M., Wojtalik, J. A., Keshavan, M. S., & Minshew, N. J. (2017). Social-cognitive brain function and connectivity during visual perspective-taking in autism and schizophrenia. Schizophrenia Research, 183, 102–109.CrossRefPubMed

Epskamp, S., Borsboom, D., & Fried, E. I. (2018). Estimating psychological networks and their accuracy: A tutorial paper. Behavior Research Methods, 50(1), 195–212.CrossRefPubMed

Epskamp, S., Cramer, A. O., Waldorp, L. J., Schmittmann, V. D., & Borsboom, D. (2012). qgraph: Network visualizations of relationships in psychometric data. Journal of Statistical Software, 48(1), 1–18.

Fernandes, J. M., Cajão, R., Lopes, R., Jerónimo, R., & Barahona-Corrêa, J. B. (2018). Social cognition in schizophrenia and autism spectrum disorders: A systematic review and meta-analysis of direct comparisons. Frontiers in Psychiatry, 9, 504.CrossRefPubMedPubMedCentral

Foss-Feig, J. H., McPartland, J. C., Anticevic, A., & Wolf, J. (2016). Re-conceptualizing ASD within a dimensional framework: Positive, negative, and cognitive feature clusters. Journal of Autism and Developmental Disorders, 46(1), 342–351.CrossRefPubMedPubMedCentral

Herdin, M., Czink, N., Ozcelik, H., & Bonek, E. (2005). Correlation matrix distance, a meaningful measure for evaluation of non-stationary MIMO channels. 2005 IEEE 61st Vehicular Technology Conference,

Hoffman, R. E. (2007). A social deafferentation hypothesis for induction of active schizophrenia. Schizophrenia Bulletin, 33(5), 1066–1070.CrossRefPubMedPubMedCentral

Hooley, J. M. (2010). Social factors in schizophrenia. Current Directions in Psychological Science, 19(4), 238–242.CrossRef

Insel, T., Cuthbert, B., Garvey, M., Heinssen, R., Pine, D. S., Quinn, K., Sanislow, C., & Wang, P. (2010). Research domain criteria (RDoC): Toward a new classification framework for research on mental disorders. The American Psychiatric Association, 167(7), 748–751. https://doi.org/10.1176/appi.ajp.2010.09091379CrossRef

Jones, P. (2017). Networktools: Assorted tools for identifying important nodes in networks. R package version 1.1. 0. Computer Software. Retrieved from https://CRAN.Rproject.org/package=networktools

Kass, R. E., & Raftery, A. E. (1995). Bayes factors. Journal of the American Statistical Association, 90(430), 773–795.CrossRef

Kästner, A., Begemann, M., Michel, T. M., Everts, S., Stepniak, B., Bach, C., Poustka, L., Becker, J., Banaschewski, T., & Dose, M. (2015). Autism beyond diagnostic categories: Characterization of autistic phenotypes in schizophrenia. BMC Psychiatry, 15(1), 1–12.CrossRef

Kay, S. R., Fiszbein, A., & Opler, L. A. (1987). The Positive and Negative Syndrome Scale (PANSS) for schizophrenia. Schizophrenia Bulletin, 13(2), 261–276. https://doi.org/10.1093/schbul/13.2.261CrossRefPubMed

Kurtz, M. M., & Mueser, K. T. (2008). A meta-analysis of controlled research on social skills training for schizophrenia. Journal of Consulting and Clinical Psychology, 76(3), 491.CrossRefPubMed

Lauritzen, S. L., & Wermuth, N. (1989). Graphical models for associations between variables, some of which are qualitative and some quantitative. The Annals of Statistics, 17(1), 31–57. https://doi.org/10.1214/aos/1176347003CrossRef

Lord, C., Rutter, M., DiLavore, P., Risi, S., Gotham, K., & Bishop, S. (2012). Autism diagnostic observation schedule,(ADOS-2) modules 1–4. Western Psychological Services.

Martínez, A., Tobe, R., Dias, E. C., Ardekani, B. A., Veenstra-VanderWeele, J., Patel, G., Breland, M., Lieval, A., Silipo, G., & Javitt, D. C. (2019). Differential patterns of visual sensory alteration underlying face emotion recognition impairment and motion perception deficits in schizophrenia and autism spectrum disorder. Biological Psychiatry, 86(7), 557–567.CrossRefPubMedPubMedCentral

Mastrovito, D., Hanson, C., & Hanson, S. J. (2018). Differences in atypical resting-state effective connectivity distinguish autism from schizophrenia. NeuroImage: Clinical, 18, 367–376.CrossRefPubMed

Mazefsky, C., Kao, J., & Oswald, D. (2011). Preliminary evidence suggesting caution in the use of psychiatric self-report measures with adolescents with high-functioning autism spectrum disorders. Research in Autism Spectrum Disorders, 5(1), 164–174.CrossRefPubMedPubMedCentral

McNally, R. J. (2016). Can network analysis transform psychopathology? Behaviour Research and Therapy, 86, 95–104.CrossRefPubMed

McNally, R. J. (2021). Network analysis of psychopathology: Controversies and challenges. Annual Review of Clinical Psychology, 17, 31–53.CrossRefPubMed

Oliver, L. D., Moxon-Emre, I., Lai, M.-C., Grennan, L., Voineskos, A. N., & Ameis, S. H. (2021). Social cognitive performance in schizophrenia spectrum disorders compared with autism spectrum disorder: A systematic review, meta-analysis, and meta-regression. JAMA Psychiatry, 78(3), 281–292. https://doi.org/10.1001/jamapsychiatry.2020.3908CrossRefPubMed

Pinkham, A. E., Hopfinger, J. B., Pelphrey, K. A., Piven, J., & Penn, D. L. (2008). Neural bases for impaired social cognition in schizophrenia and autism spectrum disorders. Schizophrenia Research, 99(1–3), 164–175.CrossRefPubMed

Pinkham, A. E., Morrison, K. E., Penn, D. L., Harvey, P. D., Kelsven, S., Ludwig, K., & Sasson, N. J. (2020). Comprehensive comparison of social cognitive performance in autism spectrum disorder and schizophrenia. Psychological Medicine, 50(15), 2557–2565.CrossRefPubMed

R Core Team. (2020). R: A language and environment for statistical computing. Vienna, Austria: R Foundation for Statistical Computing.

Raine, A. (1991). The SPQ: a scale for the assessment of schizotypal personality based on DSM-III-R criteria. Schizophrenia Bulletin, 17(4), 555–564.CrossRefPubMed

Robinaugh, D. J., Millner, A. J., & McNally, R. J. (2016). Identifying highly influential nodes in the complicated grief network. Journal of Abnormal Psychology, 125(6), 747.CrossRefPubMedPubMedCentral

Sasson, N. J., Pinkham, A. E., Weittenhiller, L. P., Faso, D. J., & Simpson, C. (2016). Context effects on facial affect recognition in schizophrenia and autism: Behavioral and eye-tracking evidence. Schizophrenia Bulletin, 42(3), 675–683.CrossRefPubMed

Sobel, M. E. (1997). Measurement, causation and local independence in latent variable models. Latent variable modeling and applications to causality (pp. 11–28). Springer.CrossRef

Spain, D., & Blainey, S. H. (2015). Group social skills interventions for adults with high-functioning autism spectrum disorders: A systematic review. Autism, 19(7), 874–886.CrossRefPubMed

St Pourcain, B., Robinson, E. B., Anttila, V., Sullivan, B. B., Maller, J., Golding, J., Skuse, D., Ring, S., Evans, D. M., & Zammit, S. (2018). ASD and schizophrenia show distinct developmental profiles in common genetic overlap with population-based social communication difficulties. Molecular Psychiatry, 23(2), 263–270.CrossRefPubMed

Tordjman, S., Celume, M., Denis, L., Motillon, T., & Keromnes, G. (2019). Reframing schizophrenia and autism as bodily self-consciousness disorders leading to a deficit of theory of mind and empathy with social communication impairments. Neuroscience & Biobehavioral Reviews, 103, 401–413.CrossRef

Trevisan, D. A., Foss-Feig, J. H., Naples, A. J., Srihari, V., Anticevic, A., & McPartland, J. C. (2020). Autism spectrum disorder and schizophrenia are better differentiated by positive symptoms than negative symptoms. Frontiers in Psychiatry, 11, 548.CrossRefPubMedPubMedCentral

Wible, C. G. (2012). Schizophrenia as a disorder of social communication. Schizophrenia Research and Treatment. https://doi.org/10.1155/2012/920485CrossRefPubMedPubMedCentral

Williams, D. R., & Mulder, J. (2019). Bggm: AR package for bayesian gaussian graphical models.

Williams, D. R., & Mulder, J. (2020). BGGM: Bayesian Gaussian graphical models in R. Journal of Open Source Software, 5(51), 2111.CrossRef

Williams, D. R., Rast, P., Pericchi, L. R., & Mulder, J. (2020). Comparing Gaussian graphical models with the posterior predictive distribution and Bayesian model selection. Psychological Methods, 25(5), 653.CrossRefPubMedPubMedCentral

Zhou, H.-Y., Yang, H.-X., Gong, J.-B., Cheung, E. F., Gooding, D. C., Park, S., & Chan, R. C. (2019). Revisiting the overlap between autistic and schizotypal traits in the non-clinical population using meta-analysis and network analysis. Schizophrenia Research, 212, 6–14.CrossRefPubMed

Titel: Distinct Symptom Network Structure and Shared Central Social Communication Symptomatology in Autism and Schizophrenia: A Bayesian Network Analysis
Auteurs: Gloria T. Han
Dominic A. Trevisan
Jennifer Foss-Feig
Vinod Srihari
James C. McPartland
Publicatiedatum: 25-06-2022
Uitgeverij: Springer US
Gepubliceerd in: Journal of Autism and Developmental Disorders / Uitgave 9/2023
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI: https://doi.org/10.1007/s10803-022-05620-0

Bohn Stafleu van Loghum

Deel dit onderdeel of sectie (kopieer de link)

Abstract

Log in om toegang te krijgen

Andere artikelen Uitgave 9/2023

Effects of Intersectionality Along the Pathway to Diagnosis for Autistic Children With and Without Co-occurring Attention Deficit Hyperactivity Disorder in a Nationally-Representative Sample

Are there gender-based variations in the presentation of Autism amongst female and male children?

Expanding on “Screening, Diagnosis, and Intervention for Autism: Experiences of Black and Multiracial Families Seeking Care” to Support BIPOC Autistic Postsecondary Students

Developing the Parent-Coaching Assessment, Individualization, and Response to Stressors (PAIRS) Tool for Behavior Analysts

Whose Gestures are More Predictive of Expressive Language Abilities among Chinese-Speaking Children with Autism? A Comparison of Caregivers’ and Children’s Gestures

Cognitive predictors of Social processing in congenital atypical development