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14-08-2017

Comparison of health state values derived from patients and individuals from the general population

Auteurs: Mihir Gandhi, Ru San Tan, Raymond Ng, Su Pin Choo, Whay Kuang Chia, Chee Keong Toh, Carolyn Lam, Phong Teck Lee, Nang Khaing Zar Latt, Kim Rand-Hendriksen, Yin Bun Cheung, Nan Luo

Gepubliceerd in: Quality of Life Research | Uitgave 12/2017

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Abstract

Purpose

Utility values are critical for cost-utility analyses that guide healthcare decisions. We aimed to compare the utility values of the 5-level EuroQoL-5Dimension (EQ-5D-5L) health states elicited from members of the general public and patients with heart disease or cancer.

Methods

In face-to-face interviews with 157 heart disease patients, 169 cancer patients, and 169 members from the general population, participants valued 10 EQ-5D-5L health states using a composite Time Trade-Off method.

Results

Pooling utility values for all health states, heart disease patients and cancer patients had mean utility values lower by 0.11 points (P value = 0.014) and 0.06 points (P value = 0.148), respectively, compared to the general population. Adjusting for sociodemographic characteristics, differences in health state utility values between the patient and the general populations were rendered non-significant, except that heart disease patients gave higher utility values (mean difference = 0.08; P value = 0.007) to mild health states than the general population. Difference in utility values, defined as utility value of a better health state minus that of a poorer health state, was higher among heart disease patients compared to the general population, before and after adjusting for sociodemographic characteristics.

Conclusions

Patients may differ from members of the general population in the strength of their preferences for hypothetical health states. Using utility values derived from the general population may under-estimate the comparative effectiveness of healthcare interventions for certain diseases, such as heart diseases.
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Metagegevens
Titel
Comparison of health state values derived from patients and individuals from the general population
Auteurs
Mihir Gandhi
Ru San Tan
Raymond Ng
Su Pin Choo
Whay Kuang Chia
Chee Keong Toh
Carolyn Lam
Phong Teck Lee
Nang Khaing Zar Latt
Kim Rand-Hendriksen
Yin Bun Cheung
Nan Luo
Publicatiedatum
14-08-2017
Uitgeverij
Springer International Publishing
Gepubliceerd in
Quality of Life Research / Uitgave 12/2017
Print ISSN: 0962-9343
Elektronisch ISSN: 1573-2649
DOI
https://doi.org/10.1007/s11136-017-1683-5

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