Skip to main content


Swipe om te navigeren naar een ander artikel

14-08-2017 | Uitgave 12/2017

Quality of Life Research 12/2017

Comparison of health state values derived from patients and individuals from the general population

Quality of Life Research > Uitgave 12/2017
Mihir Gandhi, Ru San Tan, Raymond Ng, Su Pin Choo, Whay Kuang Chia, Chee Keong Toh, Carolyn Lam, Phong Teck Lee, Nang Khaing Zar Latt, Kim Rand-Hendriksen, Yin Bun Cheung, Nan Luo
Belangrijke opmerkingen

Electronic supplementary material

The online version of this article (doi:10.​1007/​s11136-017-1683-5) contains supplementary material, which is available to authorized users.



Utility values are critical for cost-utility analyses that guide healthcare decisions. We aimed to compare the utility values of the 5-level EuroQoL-5Dimension (EQ-5D-5L) health states elicited from members of the general public and patients with heart disease or cancer.


In face-to-face interviews with 157 heart disease patients, 169 cancer patients, and 169 members from the general population, participants valued 10 EQ-5D-5L health states using a composite Time Trade-Off method.


Pooling utility values for all health states, heart disease patients and cancer patients had mean utility values lower by 0.11 points (P value = 0.014) and 0.06 points (P value = 0.148), respectively, compared to the general population. Adjusting for sociodemographic characteristics, differences in health state utility values between the patient and the general populations were rendered non-significant, except that heart disease patients gave higher utility values (mean difference = 0.08; P value = 0.007) to mild health states than the general population. Difference in utility values, defined as utility value of a better health state minus that of a poorer health state, was higher among heart disease patients compared to the general population, before and after adjusting for sociodemographic characteristics.


Patients may differ from members of the general population in the strength of their preferences for hypothetical health states. Using utility values derived from the general population may under-estimate the comparative effectiveness of healthcare interventions for certain diseases, such as heart diseases.

Log in om toegang te krijgen

Met onderstaand(e) abonnement(en) heeft u direct toegang:

BSL Podotherapeut Totaal

Binnen de bundel kunt u gebruik maken van boeken, tijdschriften, e-learnings, web-tv's en uitlegvideo's. BSL Podotherapeut Totaal is overal toegankelijk; via uw PC, tablet of smartphone.

Extra materiaal
Supplementary material 1 (DOCX 35 kb)
Over dit artikel

Andere artikelen Uitgave 12/2017

Quality of Life Research 12/2017 Naar de uitgave