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15-06-2022 | Original Article

Brain Anatomy in Boys with Conduct Disorder: Differences Among Aggression Subtypes

Auteurs: Yali Jiang, Yidian Gao, Daifeng Dong, Xiaoqiang Sun, Weijun Situ, Shuqiao Yao

Gepubliceerd in: Child Psychiatry & Human Development | Uitgave 1/2024

Abstract

Aggression is a core feature of conduct disorder (CD), but the motivation, execution of aggression may vary. A deeper understanding of the neural substrates of aggressive behaviours is critical for effective clinical intervention. Seventy-six Boys with CD (50 with impulsive aggression (I-CD) and 26 with premeditated aggression (P-CD)) and 69 healthy controls (HCs) underwent a structural MRI scan and behavioural assessments. Whole-brain analyses revealed that, compared to HCs, the I-CD group showed significant cortical thinning in the right frontal cortex, while the P-CD group demonstrated significant folding deficits in the bilateral superior parietal cortex. Both types of aggression negatively correlated with the left amygdala volume, albeit in different ways. The present results demonstrated that the complex nature of aggression relies on differentiated anatomical substrates, highlighting the importance of exploring differential circuit-targeted interventions for CD patients.

vorige artikel “We are Family”: Remembering Siblings of Youth with Psychiatric Concerns

volgende artikel The Moderating Role of Maternal Praise and Positivity in the Association Between Callous-Unemotional (CU) Traits and Later Aggression: A Prospective Study in Preschool Children in Colombia

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Titel: Brain Anatomy in Boys with Conduct Disorder: Differences Among Aggression Subtypes
Auteurs: Yali Jiang
Yidian Gao
Daifeng Dong
Xiaoqiang Sun
Weijun Situ
Shuqiao Yao
Publicatiedatum: 15-06-2022
Uitgeverij: Springer US
Gepubliceerd in: Child Psychiatry & Human Development / Uitgave 1/2024
Print ISSN: 0009-398X
Elektronisch ISSN: 1573-3327
DOI: https://doi.org/10.1007/s10578-022-01360-5

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