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01-10-2006 | Original paper

Autonomic and Neuroendocrine Responses to a Psychosocial Stressor in Adults with Autistic Spectrum Disorder

Auteurs: Lucres M. C. Jansen, Christine C. Gispen-de Wied, Victor M. Wiegant, Herman G. M. Westenberg, Bertine E. Lahuis, Herman van Engeland

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 7/2006

Abstract

Objective of the study was to replicate in adults our previous findings of decreased heart rate and normal endocrine responses to stress in autistic children and to elucidate the discrepancy between autonomic and endocrine stress responses by including epinephrine, norepinephrine, oxytocin and vasopressin measurements. Ten autistic spectrum disorder (ASD) adults were compared to 14 healthy controls in their response to a psychosocial stressor (public speaking). ASD patients showed decreased heart rate, but normal cortisol responses, consistent with our prior findings in children. No differences in norepinephrine, epinephrine, oxytocin or vasopressin responses to stress were found. However, in contrast to previous findings in low functioning autistic children, ASD adults showed increased basal oxytocin levels, which may be related to developmental factors.

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Titel: Autonomic and Neuroendocrine Responses to a Psychosocial Stressor in Adults with Autistic Spectrum Disorder
Auteurs: Lucres M. C. Jansen
Christine C. Gispen-de Wied
Victor M. Wiegant
Herman G. M. Westenberg
Bertine E. Lahuis
Herman van Engeland
Publicatiedatum: 01-10-2006
Uitgeverij: Springer US
Gepubliceerd in: Journal of Autism and Developmental Disorders / Uitgave 7/2006
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI: https://doi.org/10.1007/s10803-006-0124-z

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