Skip to main content


Swipe om te navigeren naar een ander artikel

04-02-2019 | OriginalPaper | Uitgave 6/2019 Open Access

Journal of Autism and Developmental Disorders 6/2019

Autism With and Without Regression: A Two-Year Prospective Longitudinal Study in Two Population-Derived Swedish Cohorts

Journal of Autism and Developmental Disorders > Uitgave 6/2019
Lucy Thompson, Christopher Gillberg, Sara Landberg, Anne-Katrin Kantzer, Carmela Miniscalco, Martina Barnevik Olsson, Mats A. Eriksson, Elisabeth Fernell
Belangrijke opmerkingen
Lucy Thompson and Christopher Gillberg are joint first authors.

Publisher’s Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.


Two community-based cohorts of children with autism spectrum disorder, examined using similar assessment protocols, were pooled (n = 301) and subdivided according to history of regression. Those with regression (n = 62), 20.5% of the combined cohort, were contrasted with those without regression (n = 241) at first assessment (age range 19–60 months) and at 2-year follow-up on a range of measures. The regression group was significantly more functionally impaired, with regard to intellectual function (p < .001), language development (p < .001), and to severity of autism (p < .01) at both T1 and T2. Only 14 (23.3%) had a clearly identified underlying etiology [24 (18.6%) in the non-regressive group]. There were no significant differences between those who had regressed ‘from normal’ and those who had regressed ‘from low’ functioning.

Onze productaanbevelingen

BSL Psychologie Totaal

Met BSL Psychologie Totaal blijf je als professional steeds op de hoogte van de nieuwste ontwikkelingen binnen jouw vak. Met het online abonnement heb je toegang tot een groot aantal boeken, protocollen, vaktijdschriften en e-learnings op het gebied van psychologie en psychiatrie. Zo kun je op je gemak en wanneer het jou het beste uitkomt verdiepen in jouw vakgebied.

Over dit artikel

Andere artikelen Uitgave 6/2019

Journal of Autism and Developmental Disorders 6/2019 Naar de uitgave