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Gepubliceerd in: Journal of Autism and Developmental Disorders 6/2019

05-02-2019 | Original Paper

EEG Abnormalities as a Neurophysiological Biomarker of Severity in Autism Spectrum Disorder: A Pilot Cohort Study

Auteurs: Antonio Gennaro Nicotera, Randi Jenssen Hagerman, Maria Vincenza Catania, Serafino Buono, Santo Di Nuovo, Elisa Maria Liprino, Emanuela Stracuzzi, Stefania Giusto, Giuseppina Di Vita, Sebastiano Antonino Musumeci

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 6/2019

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Abstract

To date, the phenotypic significance of EEG abnormalities in patients with ASD is unclear. In a population affected by ASD we aimed to evaluate: the phenotypic characteristics; the prevalence of EEG abnormalities; the potential correlations between EEG abnormalities and behavioral and cognitive variables. Sixty-nine patients with ASD underwent cognitive or developmental testing, language assessment, and adaptive behavior skills evaluation as well as sleep/wake EEG recording. EEG abnormalities were found in 39.13% of patients. EEG abnormalities correlated with autism severity, hyperactivity, anger outbursts, aggression, negative or destructive behavior, motor stereotypies, intellectual disability, language impairment and self-harm. Our findings confirmed that EEG abnormalities are present in the ASD population and correlate with several associated phenotypic features.
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Metagegevens
Titel
EEG Abnormalities as a Neurophysiological Biomarker of Severity in Autism Spectrum Disorder: A Pilot Cohort Study
Auteurs
Antonio Gennaro Nicotera
Randi Jenssen Hagerman
Maria Vincenza Catania
Serafino Buono
Santo Di Nuovo
Elisa Maria Liprino
Emanuela Stracuzzi
Stefania Giusto
Giuseppina Di Vita
Sebastiano Antonino Musumeci
Publicatiedatum
05-02-2019
Uitgeverij
Springer US
Gepubliceerd in
Journal of Autism and Developmental Disorders / Uitgave 6/2019
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI
https://doi.org/10.1007/s10803-019-03908-2

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