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Gepubliceerd in: Journal of Autism and Developmental Disorders 12/2023

10-09-2022 | Original Paper

Validity and Cutoff Score of the Autism Mental Status Exam for an Autism Spectrum Disorder Diagnosis in Chinese Children

Auteurs: Shuran Yang, Dong Han, Huizhi Zhou, Chen Yang, Kun Zhang, Shi Chen, Runxu Yang, Xia Cao, David Grodberg, Xudong Zhao, Chuanyuan Kang

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 12/2023

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Abstract

The Autism Mental Status exam (AMSE) has demonstrated excellent sensitivity and specificity in Western high-risk population with suspected autism spectrum disorder (ASD). This study aimed to evaluate the psychometric properties of the AMSE in a sample of high-risk Chinese children, and to determine the optimal cutoff score of the Chinese version of the AMSE in supporting ASD diagnosis. 66 young children aged from 2 to 11 years with suspected ASD were enrolled in the present study. A diagnosis of ASD or non-ASD was determined by a Best Estimate Diagnosis protocol according to the DSM-5 criteria. Receiver operating characteristic (ROC) curve analysis was conducted to assess the validity of the AMSE and search for the most effective cutoff score. The ROC curve analysis yields the area under the ROC curve of 0.98 which represents excellent diagnostic accuracy. Findings indicate the optimal cutoff score of the Chinese version of the AMSE was estimated as 6, producing the highest sensitivity of 98% and a specificity of 87%. Preliminary findings of the study suggest the AMSE has promising psychometric properties as an assessment tool for identifying ASD symptoms and supporting diagnostic decision-making in high-risk Chinese children population.
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Metagegevens
Titel
Validity and Cutoff Score of the Autism Mental Status Exam for an Autism Spectrum Disorder Diagnosis in Chinese Children
Auteurs
Shuran Yang
Dong Han
Huizhi Zhou
Chen Yang
Kun Zhang
Shi Chen
Runxu Yang
Xia Cao
David Grodberg
Xudong Zhao
Chuanyuan Kang
Publicatiedatum
10-09-2022
Uitgeverij
Springer US
Gepubliceerd in
Journal of Autism and Developmental Disorders / Uitgave 12/2023
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI
https://doi.org/10.1007/s10803-022-05730-9

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