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Gepubliceerd in: Child Psychiatry & Human Development 5/2023

24-02-2022 | Original Article

Trends in Prescribing Antipsychotics for Children and Adolescents in Japan: A Descriptive Epidemiological Study Using a Large-Scale Pharmacy Dataset

Auteurs: Sayuri Nakane, Sachiko Tanaka-Mizuno, Chika Nishiyama, Kenji Kochi, Madoka Yamamoto-Sasaki, Masato Takeuchi, Yusuke Ogawa, Yuko Doi, Masaru Arai, Yosuke Fujii, Toshiyuki Matsunaga, Toshiaki A. Furukawa, Koji Kawakami

Gepubliceerd in: Child Psychiatry & Human Development | Uitgave 5/2023

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Abstract

Little is known about antipsychotic prescription patterns among children and adolescents in Japan, particularly in outpatient settings. We investigated the prevalence and trends of antipsychotic prescription for outpatients aged ≤ 17 years receiving a first antipsychotic prescription from 2006 to 2012 based on a large-scale dispensation dataset. Measurements included age, sex, department of diagnosis and treatment, type of prescription (monotherapy or polytherapy), antipsychotic dosage, and concomitant psychotropic drugs. Of the 10,511 patients, 65.1% were aged 13–17 years, and 52.9% were males. Second-generation antipsychotic monotherapy prescriptions increased from 53.8% in 2006 to 78.3% in 2012. Risperidone was the most frequently prescribed antipsychotic, followed by aripiprazole and olanzapine. Approximately 25.0% of patients were prescribed an initial dose less than recommended. Second-generation antipsychotic monotherapy is currently the most frequent prescription pattern among outpatients aged ≤ 17 years receiving an initial antipsychotic prescription.
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Metagegevens
Titel
Trends in Prescribing Antipsychotics for Children and Adolescents in Japan: A Descriptive Epidemiological Study Using a Large-Scale Pharmacy Dataset
Auteurs
Sayuri Nakane
Sachiko Tanaka-Mizuno
Chika Nishiyama
Kenji Kochi
Madoka Yamamoto-Sasaki
Masato Takeuchi
Yusuke Ogawa
Yuko Doi
Masaru Arai
Yosuke Fujii
Toshiyuki Matsunaga
Toshiaki A. Furukawa
Koji Kawakami
Publicatiedatum
24-02-2022
Uitgeverij
Springer US
Gepubliceerd in
Child Psychiatry & Human Development / Uitgave 5/2023
Print ISSN: 0009-398X
Elektronisch ISSN: 1573-3327
DOI
https://doi.org/10.1007/s10578-022-01330-x

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