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Quality of Life Research

Gepubliceerd in:

13-02-2023

Quantifying health-related quality of life in Malaysian type 2 diabetes: focusing on complication types and severity

Auteurs: Michelle Hwee Pheng Tan, Siew Chin Ong, Annushiah Vasan Thakumar, Norlaila Mustafa

Gepubliceerd in: Quality of Life Research | Uitgave 7/2023

Abstract

Purpose

There is a knowledge gap of health utility values for Type 2 Diabetes Mellitus (T2DM) complications in Malaysia. This study aimed to estimate EQ-5D-5L utility values and evaluate health-related quality of life (HRQoL) for Malaysian T2DM associated with complications and clinical characteristics.

Methods

A cross-sectional study was conducted on T2DM patients at a tertiary hospital outpatient using the Malay and English version of the EQ-5D-5L questionnaire. Health utility values were derived using the Malaysian EQ-5D-5L value set. Ordinary least squares (OLS) multivariable regression model was used to estimate the health utility decrements associated with T2DM-related complications and clinical characteristics.

Results

A total of 513 T2DM patients were recruited. Overall, pain was the most affected of all five EQ-5D-5L dimensions. Patients with foot ulcer, amputation, severe heart failure and frequent hypoglycemia reported more problems collectively in all EQ-5D-5L dimensions. Older age, lower education level, longer duration of T2DM, urine protein creatine index (UPCI) > 0.02 g/mmol, and injection therapy were significantly associated with lower EQ-5D-5L utility values (p < 0.004, Bonferroni adjusted). The lowest unadjusted utility values were reported for severe heart failure 0.65 (interquartile range, IQR 0.50), frequent hypoglycemia 0.74 (0.22) and being amputated 0.78 (0.47). In the multivariable regression model after controlling for sociodemographic and clinical characteristics, the largest utility value decrement was observed for amputation (− 0.158, SE 0.087, p = 0.05), frequent hypoglycemia (− 0.101, SE 0.030, p = 0.001), myocardial infarction (-0.050, SE 0.022, p = 0.022) and obesity (-0.034, SE 0.016, p = 0.029).

Conclusion

Larger utility value decrements were found for severe stages of complications. These findings suggest the value of defining severity of complications in utility elicitation studies. The utility decrement quantified for different T2DM complication severity will be useful for economic evaluations within diabetic-related fields.

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World Health Organisation. (2021). Retrieved from https://www.who.int/news-room/fact-sheets/detail/noncommunicable-diseases

Zhang, P., Zhang, X., Brown, J., Vistisen, D., Sicree, R., Shaw, J., & Nichols, G. (2010). Global healthcare expenditure on diabetes for 2010 and 2030. Diabetes research and clinical practice, 87(3), 293–301. https://doi.org/10.1016/J.DIABRES.2010.01.026CrossRefPubMed

IDF Diabetes Atlas | Tenth Edition. (n.d.). Retrieved July 7, 2022, from https://diabetesatlas.org/

Ganasegeran, K., Hor, C. P., Jamil, M. F. A., Loh, H. C., Noor, J. M., Hamid, N. A., Suppiah, P. D., Abdul Manaf, M. R., Ch’ng, A. S. H., & Looi, I. (2020). A systematic review of the economic burden of type 2 diabetes in Malaysia. International Journal of Enviromental Research Public Health. https://doi.org/10.3390/ijerph17165723CrossRef

Arnold, R. J. G. (2021). Pharmacoeconomics_ From Theory to Practice (2nd ed.).

Whitehead, S. J., & Ali, S. (2010). Health outcomes in economic evaluation: The QALY and utilities. British Medical Bulletin, 96(1), 5–21. https://doi.org/10.1093/bmb/ldq033CrossRefPubMed

EuroQol group. (n.d.). Retrieved April 2021, from https://euroqol.org/

Devlin, N. J. (2020). EQ5D Methods For Analysing And Reporting.

Solli, O., Stavem, K., & Kristiansen, I. S. (2010). Health-related quality of life in diabetes: The associations of complications with EQ-5D scores. Health and Quality of Life Outcomes, 8, 18. https://doi.org/10.1186/1477-7525-8-18CrossRefPubMedPubMedCentral

10.

Jiao, F. F., Wong, C. K. H., Gangwani, R., Tan, K. C. B., Tang, S. C. W., & Lam, C. L. K. (2017). Health-related quality of life and health preference of Chinese patients with diabetes mellitus managed in primary care and secondary care setting: decrements associated with individual complication and number of complications. Health and Quality of Life Outcomes. https://doi.org/10.1186/s12955-017-0699-4CrossRefPubMedPubMedCentral

11.

Takahara, M., Katakami, N., Shiraiwa, T., Abe, K., Ayame, H., Ishimaru, Y., Iwamoto, M., Shimizu, M., Tomonaga, O., Yokoyama, H., Matsuoka, T. A., & Shimomura, I. (2019). Evaluation of health utility values for diabetic complications, treatment regimens, glycemic control and other subjective symptoms in diabetic patients using the EQ-5D-5L. Acta Diabetologica, 56(3), 309–319. https://doi.org/10.1007/s00592-018-1244-6CrossRefPubMed

12.

Zhang, P., Brown, M. B., Bilik, D., Ackermann, R. T., Li, R., & Herman, W. H. (2012). Health utility scores for people with type 2 diabetes in US managed care health plans results from translating research into action for diabetes (TRIAD). Diabetes Care, 35(11), 2250–2256. https://doi.org/10.2337/dc11-2478CrossRefPubMedPubMedCentral

13.

Dhillon, H., Nordin, R. B., & Ramadas, A. (2019). Quality of life and associated factors among primary care asian patients with type 2 diabetes mellitus. International Journal of Environmental Research and Public Health. https://doi.org/10.3390/ijerph16193561CrossRefPubMedPubMedCentral

14.

Daher, A. M., AlMashoor, S. A. H., & Winn, T. (2015). Glycaemic control and quality of life among ethnically diverse Malaysian diabetic patients. Quality of Life Research : An International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation, 24(4), 951–958. https://doi.org/10.1007/S11136-014-0830-5CrossRefPubMed

15.

Gillani, S. W., Ansari, I. A., Zaghloul, H. A., Sulaiman, S. A. S., Rathore, H. A., Baig, M. R., Abdul, M. I. M., & Althagfan, S. (2019). Predictors of Health-Related Quality of Life Among Patients with type II diabetes mellitus who are insulin users: A multidimensional model. Current Therapeutic Research, 90, 53–60. https://doi.org/10.1016/j.curtheres.2019.04.001CrossRefPubMedPubMedCentral

16.

Goh, S. G. K., Rusli, B. N., & Khalid, B. A. K. (2015). Diabetes quality of life perception in a multiethnic population. Quality of Life Research, 24(7), 1677–1686. https://doi.org/10.1007/s11136-014-0885-3CrossRefPubMed

17.

Goh, S. G., Rusli, B. N., & Khalid, B. A. (2015). Development and validation of the Asian diabetes quality of life (AsianDQOL) questionnaire. Diabetes Research and Clinical Practice, 108(3), 489–498. https://doi.org/10.1016/j.diabres.2015.02.009CrossRefPubMed

18.

Jusoh, Z., Tohid, H., Omar, K., Muhammad, N. A., & Ahmad, S. (2018). Clinical and sociodemographic predictors of the quality of life among patients with type 2 diabetes mellitus on the east coast of peninsular Malaysia. The Malaysian Journal of Medical Sciences: MJMS, 25(1), 84. https://doi.org/10.21315/MJMS2018.25.1.10CrossRefPubMedPubMedCentral

19.

Daher, A. M., AlMashoor, S. H., & Winn, T. (2016). Performance of the Malay audit of diabetes dependent quality of life-18 and associates of quality of life among patients with type 2 diabetes mellitus from major ethnic groups of Malaysia. PLoS One, 11(10), e0163701. https://doi.org/10.1371/journal.pone.0163701CrossRefPubMedPubMedCentral

20.

Zhang, Y., Wu, J., Chen, Y., & Shi, L. (2020). EQ-5D-3L decrements by diabetes complications and comorbidities in China. Diabetes Therapy : Research, Treatment and Education of Diabetes and Related Disorders, 11(4), 939–950. https://doi.org/10.1007/s13300-020-00788-zCrossRefPubMed

21.

Yang, Z., Purba, F. D., Shafie, A. A., Igarashi, A., Wong, E. L., Lam, H., Van Minh, H., Lin, H. W., Ahn, J., Pattanaphesaj, J., Jo, M. W., Mai, V. Q., Busschbach, J., Luo, N., & Jiang, J. (2022). Do health preferences differ among Asian populations? A comparison of EQ-5D-5L discrete choice experiments data from 11 Asian studies. Quality of Life Research : An International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation. https://doi.org/10.1007/S11136-021-03075-XCrossRefPubMed

22.

Shafie, A. A., Vasan Thakumar, A., Lim, C. J., Luo, N., Rand-Hendriksen, K., & Md Yusof, F. A. (2019). EQ-5D-5L valuation for the malaysian population. PharmacoEconomics, 37(5), 715–725. https://doi.org/10.1007/s40273-018-0758-7CrossRefPubMed

23.

Faul, F., Erdfelder, E., Lang, A. G., & Buchner, A. (2007). G*Power 3: A flexible statistical power analysis program for the social, behavioral, and biomedical sciences. Behavior Research Methods, 39(2), 175–191. https://doi.org/10.3758/BF03193146CrossRefPubMed

24.

Ishii, H., Takamura, H., Nishioka, Y., Langer, J., Watanabe, M., Kim, H. R., & Crawford, B. (2020). Quality of life and utility values for cost-effectiveness modeling in Japanese patients with type 2 diabetes. Diabetes Therapy, 11(12), 2931–2943. https://doi.org/10.1007/s13300-020-00938-3CrossRefPubMedPubMedCentral

25.

(2019) Clinical Practice Guideline Management Of T2DM 6th Edition. Ministry of Health Malaysia (Vol. 53).

26.

American Diabetes Association. (2018).Diabetes Care. Retrieved from https://www.diabetes.org/

27.

National Institute for Health and Care Excellence [NICE]. (2022).

28.

Pallant, J. (2022). SPSS Survival Manual: A Step by Step Guide to Data Analysis Using IBM SPSS (7th edn).

29.

Sullivan, G. M., & Feinn, R. (2012). Using effect size—or why the P value is not enough. Journal of Graduate Medical Education, 4(3), 279. https://doi.org/10.4300/JGME-D-12-00156.1CrossRefPubMedPubMedCentral

30.

Hayes, A. F., & Cai, L. (2007). Using heteroskedasticity-consistent standard error estimators in OLS regression: An introduction and software implementation. Behavior Research Methods, 39(4), 709–722. https://doi.org/10.3758/BF03192961CrossRefPubMed

31.

Luk, A. O.-Y., Zhang, Y., Ko, G. T. C., Brown, N., Ozaki, R., Tong, P. C. Y., … Chan, J. C. (2014). Health-Related Quality of Life in Chinese Patients with Type 2 Diabetes: An Analysis of the Joint Asia Diabetes Evaluation (JADE) Program. Journal of diabetes & metabolism, 5, 1–7.

32.

Sakamaki, H., Ikeda, S., Ikegami, N., Uchigata, Y., Iwamoto, Y., Origasa, H., Otani, T., & Otani, Y. (2006). Measurement of HRQL using EQ-5D in patients with type 2 diabetes mellitus in Japan. Value Health, 9(1), 47–53. https://doi.org/10.1111/j.1524-4733.2006.00080.xCrossRefPubMed

33.

Yfantopoulos, J., & Chantzaras, A. (2020). Health-related quality of life and health utilities in insulin-treated type 2 diabetes: The impact of related comorbidities/complications. European Journal of Health Economics, 21(5), 729–743. https://doi.org/10.1007/s10198-020-01167-yCrossRef

34.

Sakane, N., Kotani, K., Tsuzaki, K., Nishi, M., Takahashi, K., Murata, T., Yamada, K., Okazaki, K., Yanagisawa, K., Yamada, K., Kuribayashi, N., Totsuka, Y., Hiyoshi, T., Naka, M., Sugimoto, M., Aoki, Y., Waki, M., Furuya, M., & Kitaoka,... Yamamoto T. (2015). Fear of hypoglycemia and its determinants in insulin-treated patients with type 2 diabetes mellitus. Japan Journal of Diabetes Investigation, 6, 567–570. https://doi.org/10.1111/jdi.12340CrossRefPubMed

35.

Izawa, K. P., Watanabe, S., Omiya, K., Yamada, S., Oka, K., Tamura, M., Samejima, H., Osada, N., & Iijima, S. (2005). Health-related quality of life in relation to different levels of disease severity in patients with chronic heart failure. Journal of Japan Physical Therapy Association. https://doi.org/10.1298/jjpta.8.39CrossRef

36.

Jonsson, Å., Orwelius, L., Dahlstrom, U., & Kristenson, M. (2020). Evaluation of the usefulness of EQ-5D as a patient-reported outcome measure using the Paretian classification of health change among patients with chronic heart failure. Journal of Patient-Reported Outcomes. https://doi.org/10.1186/S41687-020-00216-7CrossRefPubMedPubMedCentral

37.

Sothornwit, J., Srisawasdi, G., Suwannakin, A., & Sriwijitkamol, A. (2018). Decreased health-related quality of life in patients with diabetic foot problems. Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy, 11, 35–43. https://doi.org/10.2147/DMSO.S154304CrossRefPubMed

38.

Brennan, V. K., Mauskopf, J., Colosia, A. D., Copley-Merriman, C., Hass, B., & Palencia, R. (2015). Utility estimates for patients with Type 2 diabetes mellitus after experiencing a myocardial infarction or stroke: A systematic review. Expert Review of Pharmacoeconomics and Outcomes Research, 15(1), 111–123. https://doi.org/10.1586/14737167.2015.965152CrossRefPubMed

39.

Lambrinou, E., Hansen, T. B., & Beulens, J. W. J. (2019). Lifestyle factors, self-management and patient empowerment in diabetes care. European Journal of Preventive Cardiology, 26(2_Suppl), 55–63. https://doi.org/10.1177/2047487319885455CrossRefPubMed

40.

Butt, M., Ali, A. M., & Bakry, M. M. (2018). Health-related quality of life in poorly controlled Type 2 diabetes patients- association of patients’ characteristics with EQ-5D domains, mean EQ-5D scores, and Visual analog score. Asian Journal of Pharmaceutical and Clinical Research, 11(1), 93–98. https://doi.org/10.22159/ajpcr.2018.v11i1.19120CrossRef

41.

Shafie, A. A., Chhabra, I. K., Wong, J. H. Y., & Mohammed, N. S. (2021). EQ-5D-3L health state utility values in transfusion-dependent thalassemia patients in Malaysia: a cross-sectional assessment. Health and Quality of Life Outcomes, 2021(19), 1. https://doi.org/10.1186/S12955-020-01645-0CrossRef

42.

Puteh, S. E. W., Aizuddin, A. N., Tumian, N. R., Sathar, J., & Selamat, E. M. (2021). Health-related quality of life using EQ-5D among chronic myeloid leukaemia patients in health centres in Klang Valley Malaysia. PLOS ONE, 16(8), e0256804. https://doi.org/10.1371/JOURNAL.PONE.0256804CrossRef

43.

Olsen, J. A., & Misajon, R. (2020). A conceptual map of health-related quality of life dimensions: Key lessons for a new instrument. Quality of Life Research, 29(3), 733–743. https://doi.org/10.1007/s11136-019-02341-3CrossRefPubMed

44.

Finch, A. P., Brazier, J. E., & Mukuria, C. (2018). What is the evidence for the performance of generic preference-based measures? A systematic overview of reviews. The European Journal of health Economics : HEPAC : Health Economics in Prevention and Care, 19(4), 557–570. https://doi.org/10.1007/S10198-017-0902-XCrossRefPubMed

45.

Feng, Y. S., Kohlmann, T., Janssen, M. F., & Buchholz, I. (2021). Psychometric properties of the EQ-5D-5L: A systematic review of the literature. Quality of Life Research, 30(3), 647–673. https://doi.org/10.1007/S11136-020-02688-Y/FIGURES/4CrossRefPubMed

46.

Shim, Y. T., Lee, J., Toh, M. P. H. S., Tang, W. E., & Ko, Y. (2012). Health-related quality of life and glycaemic control in patients with Type 2 diabetes mellitus in Singapore. Diabetic medicine : a journal of the British Diabetic Association. https://doi.org/10.1111/J.1464-5491.2012.03689.XCrossRefPubMed

47.

Arifin, B., Idrus, L. R., van Asselt, A. D. I., Purba, F. D., Perwitasari, D. A., Thobari, J. A., Cao, Q., Krabbe, P. F. M., & Postma, M. J. (2019). Health-related quality of life in Indonesian type 2 diabetes mellitus outpatients measured with the Bahasa version of EQ-5D-5L · Index scores · Type 2 diabetes mellitus · Health-related quality of life · Indonesia. Quality of Life Research, 28, 1179–1190. https://doi.org/10.1007/s11136-019-02105-zCrossRefPubMedPubMedCentral

48.

Wongphan, T., & Bunthamcharoen, K. (2018). Utility weight and quality of life in thai diabetes mellitus patients measured by EQ-5D and Thai DQOL. Journal of Preventive Medicine Association of Thailand, 8(1), 121–135.

49.

Wong, E. L. Y., Xu, R. H., & Cheung, A. W. L. (2020). Measurement of health-related quality of life in patients with diabetes mellitus using EQ-5D-5L in Hong Kong China. Quality of Life Research, 29(7), 1913–1921. https://doi.org/10.1007/s11136-020-02462-0CrossRefPubMedPubMedCentral

50.

Chen, C., Chen, J.-H., Lai, T.-J., & Ko, Y. Y. (2021). Health utilities in patients with type 2 diabetes in Taiwan. Healthcare (Switzerland). https://doi.org/10.3390/healthcare9121672CrossRefPubMedCentral

51.

World Bank. (2019). Health Expenditure per capita.

52.

Al-Shorbaji, N., & Al-Shorbaji, N. (2021). Improving healthcare access through digital health: The use of information and communication technologies. Healthcare Access. https://doi.org/10.5772/INTECHOPEN.99607CrossRef

53.

Tai, S. Y., He, J. S., Kuo, C. T., & Kawachi, I. (2020). Clinical medicine urban-rural disparities in the incidence of diabetes-related complications in Taiwan: A propensity score matching analysis. Journal of Clinical Medicine. https://doi.org/10.3390/jcm9093012CrossRefPubMedPubMedCentral

54.

Koohi, F., Nedjat, S., Yaseri, M., & Cheraghi, Z. (2017). Quality of life among general populations of different countries in the past 10 years, with a focus on human development index: A Systematic review and meta-analysis. Iranian Journal of Public Health, 46(1), 12.PubMedPubMedCentral

55.

AbuAlhommos, A. K., Alturaifi, A. H., Al-Bin Hamdhah, A. M., Al-Ramadhan, H. H., Al Ali, Z. A., & Al Nasser, H. J. (2022). The health-related quality of life of patients with type 2 diabetes in Saudi Arabia. Patient preference and adherence, 16, 1233. https://doi.org/10.2147/PPA.S353525CrossRefPubMedPubMedCentral

56.

Quah, J. H., Luo, N., Ng, W. Y., How, C. H., & Tay, E. G. (2011). Health-related quality of life is associated with diabetic complications, but not with short-term diabetic control in primary care. Annals of the Academy of Medicine Singapore, 40(6), 276–286.CrossRefPubMed

57.

Svedbo Engström, M., Leksell, J., Johansson, U. B., Borg, S., Palaszewski, B., Franzén, S., Gudbjörnsdottir, S., & Eeg-Olofsson, K. (2019). Health-related quality of life and glycaemic control among adults with type 1 and type 2 diabetes - a nationwide cross-sectional study. Health and quality of life outcomes. https://doi.org/10.1186/S12955-019-1212-ZCrossRefPubMedPubMedCentral

58.

Gebremariam, G. T., Biratu, S., Alemayehu, M., Welie, A. G., Beyene, K., Sander, B., & Gebretekle, G. B. (2022). Health-related quality of life of patients with type 2 diabetes mellitus at a tertiary care hospital in Ethiopia. PLoS ONE. https://doi.org/10.1371/journal.pone.0264199CrossRefPubMedPubMedCentral

59.

Wibowo, Z. K., Mudjanarko, S. W., & Khairina, K. (2022). The relationship between diabetes distress and HbA1C level in type 2 diabetes mellitus therapy patients: a systematic review. Bali Medical Journal, 11(1), 476–484. https://doi.org/10.15562/BMJ.V11I1.2986CrossRef

60.

Kelley, K., Aricak, O. T., Light, R. P., & Agarwal, R. (2007). Proteinuria is a determinant of quality of life in diabetic nephropathy: Modeling lagged effects with path analysis. American journal of nephrology, 27(5), 488–494. https://doi.org/10.1159/000106672CrossRefPubMed

61.

Solli, O., Stavem, K., & Kristiansen, I. S. (2010). Health-related quality of life in diabetes: The associations of complications with EQ-5D scores. Health and Quality of Life Outcomes, 8(1), 18. https://doi.org/10.1186/1477-7525-8-18CrossRefPubMedPubMedCentral

62.

Group UKPDS. (1991). UK prospective diabetes study (UKPDS). Diabetologia, 34(12), 877–890. https://doi.org/10.1007/BF00400195CrossRef

63.

Clarke, P., Gray, A., & Holman, R. (2002). Estimating utility values for health states of type 2 diabetic patients using the EQ-5D (UKPDS 62). Medical Decision Making, 22(4), 340–349. https://doi.org/10.1177/0272989x0202200412CrossRefPubMed

64.

Redekop, W. K., Koopmanschap, M. A., Stolk, R. P., Rutten, G. E. H. M., Wolffenbuttel, B. H. R., & Niessen, L. W. (2002). Health-related quality of life and treatment satisfaction in dutch patients with type 2 diabetes. Diabetes Care, 25(3), 458–463. https://doi.org/10.2337/DIACARE.25.3.458CrossRefPubMed

65.

Sullivan, M. D., Anderson, R. T., Aron, D., Atkinson, H. H., Bastien, A., Chen, G. J., Feeney, P., Gafni, A., Hwang, W., Katz, L. A., Narayan, K. M., Nwachuku, C., O’Connor, P. J., & Zhang, P. (2007). Health-related quality of life and cost-effectiveness components of the action to control cardiovascular risk in diabetes (ACCORD) trial: Rationale and design. American Journal of Cardiology. https://doi.org/10.1016/j.amjcard.2007.03.027CrossRefPubMed

66.

Kiadaliri, A. A., Gerdtham, U. G., Eliasson, B., Gudbjornsdottir, S., Svensson, A. M., Carlsson, K. S., & Wordsworth, S. (2017). Health utilities of type 2 diabetes-Related complications: A cross-sectional study in Sweden. Health and Quality of Life Outcomes, 11, 4939–4952. https://doi.org/10.3390/ijerph110504939CrossRef

67.

Sothornwit, J., Srisawasdi, G., Suwannakin, A., & Sriwijitkamol, A. (2018). Decreased health-related quality of life in patients with diabetic foot problems. Diabetes Metabolic Syndrome and Obesity-Targets and Therapy, 11, 35–43. https://doi.org/10.2147/DMSO.S154304CrossRefPubMedPubMedCentral

68.

Shao, H., Yang, S., Fonseca, V., Stoecker, C., & Shi, L. (2019). Estimating quality of life decrements due to diabetes complications in the United States: The health utility index (HUI) diabetes complication equation. PharmacoEconomics, 37(7), 921–929. https://doi.org/10.1007/s40273-019-00775-8CrossRefPubMedPubMedCentral

69.

Shafie, A. A., Ng, C. H., Thanimalai, S., Haron, N., & Manocha, A. B. (2018). Estimating the utility value of hypoglycaemia according to severity and frequency using the visual analogue scale (VAS) and time trade-off (TTO) survey. Journal of Diabetes and Metabolic Disorders, 17(2), 269–275. https://doi.org/10.1007/s40200-018-0369-zCrossRefPubMedPubMedCentral

70.

Levy, A. R., Christensen, T. L. U., & Johnson, J. A. (2008). Utility values for symptomatic non-severe hypoglycaemia elicited from persons with and without diabetes in Canada and the United Kingdom. Health and Quality of Life Outcomes. https://doi.org/10.1186/1477-7525-6-73CrossRefPubMedPubMedCentral

71.

Fidler, C., Elmelund Christensen, T., Gillard, S., Nordisk, N. A., & Samantha Gillard, D. (2011). Hypoglycemia: An overview of fear of hypoglycemia, quality-of-life, and impact on costs Review Hypoglycemia: An overview of fear of hypoglycemia, quality-of-life, and impact on costs Torsten Elmelund Christensen. Journal of Medical Economics, 14(5), 646–655. https://doi.org/10.3111/13696998.2011.610852CrossRefPubMed

72.

Venkataraman, K., Wee, H. L., Leow, M. K. S., Tai, E. S., Lee, J., Lim, S. C., Tavintharan, S., Wong, T. Y., Ma, S., Heng, D., & Thumboo, J. (2013). Associations between complications and health-related quality of life in individuals with diabetes. Clinical endocrinology, 78(6), 865–873. https://doi.org/10.1111/J.1365-2265.2012.04480.XCrossRefPubMed

73.

Fenwick, E. K., Bansback, N., Gan, A. T. L., Ratcliffe, J., Burgess, L., Wong, T. Y., & Lamoureux, E. L. (2020). Validation of a novel diabetic retinopathy utility index using discrete choice experiments. British Journal of Ophthalmology, 104(2), 188–193. https://doi.org/10.1136/bjophthalmol-2019-313899CrossRefPubMed

Titel: Quantifying health-related quality of life in Malaysian type 2 diabetes: focusing on complication types and severity
Auteurs: Michelle Hwee Pheng Tan
Siew Chin Ong
Annushiah Vasan Thakumar
Norlaila Mustafa
Publicatiedatum: 13-02-2023
Uitgeverij: Springer International Publishing
Gepubliceerd in: Quality of Life Research / Uitgave 7/2023
Print ISSN: 0962-9343
Elektronisch ISSN: 1573-2649
DOI: https://doi.org/10.1007/s11136-023-03360-x

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