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01-02-2015 | Brief Communication | Uitgave 2/2015

Quality of Life Research 2/2015

Quality of life measures in Italian neurosurgical patients: validity of the EUROHIS-QOL 8-item index

Quality of Life Research > Uitgave 2/2015
Silvia Schiavolin, Rui Quintas, Paolo Ferroli, Francesco Acerbi, Stefano Brock, Alberto Cusin, Marco Schiariti, Sergio Visintini, Morgan Broggi, Matilde Leonardi, Alberto Raggi



To assess the validity, reliability and factor structure of the Italian version of the EUROHIS-QOL (European Health Interview Survey-Quality of Life) 8-item index in patients who are potential candidates for neurosurgical procedures.


Cross-sectional study. Patients completed the EUROHIS-QOL 8-item index, a disability and general well-being questionnaire; the Karnofsky performance status scale (KPS) was used as a general measure of functional status. Factor analysis was used to confirm the one-factor structure of the EUROHIS-QOL 8-item index. Reliability was measured using Cronbach’s alpha coefficient, item-total correlation and inter-item correlation. Construct validity was assessed with Pearson’s coefficient (expected to be below 0.70) and known-group analysis, dividing patients between those KPS >90 and KPS ≤90 (the latter expected to report lower QoL).


The one-factor structure was partly confirmed, with two items having low loadings. Cronbach’s alpha was 0.78; item-total correlations were below 0.70; and average inter-item correlation was 0.309. Correlations were all significant and moderate; known-group analysis shows that QoL scores were lower in patients with active symptoms (KPS ≤90).


Our findings partly confirm the factor structure and reliability of the EUROHIS-QOL 8-item index, which suggests that it may be a useful and straightforward quality of life measurement technique in neurosurgical departments.

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