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Physical activity (PA) is positively associated with numerous health benefits among cancer survivors. This study examined insufficiently investigated relationships among PA, health-related quality of life (HRQOL), and bowel function (BF) in rectal cancer survivors.
RC survivors (n = 1063) ≥5 years from diagnosis in two Kaiser permanente regions were mailed a multidimensional survey to assess HRQOL and BF. PA was assessed by a modified Godin Leisure-Time Exercise Questionnaire. PA minutes were categorized into weighted categories based on guidelines: (1) not active (zero PA minutes); (2) insufficiently active (1–149 PA minutes); (3) meeting guidelines (150–299 PA minutes); and (4) above guidelines (≥300 PA minutes). Relationships of PA with HRQOL and BF were evaluated using multiple linear regression, stratified by sex and ostomy status for BF. Types of PA identified as helpful for BF and symptoms addressed were summarized.
Response rate was 60.5%. Of 557 participants, 40% met or exceeded PA guidelines, 34% were not active, and 26% were insufficiently active. Aerobic activities, specifically walking and cycling, were most commonly reported to help BF. Higher PA was associated with better psychological wellbeing and multiple SF12 scales, worse BF scores in men with ostomies, and better BF scores in women.
Meeting or exceeding PA guidelines was associated with higher HRQOL. Although the BF findings are exploratory, they suggest women may benefit from increased PA, whereas men with ostomies may face challenges that require more study. Identifying PA strategies that will lead to improved patient compliance and benefit are needed.
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American Cancer Society. (2016). Cancer Facts & Figures 2016. Atlanta: American Cancer Society. Retrieved January 18, 2017 from http://www.cancer.org/content/dam/cancer-org/research/cancer-facts-and-statistics/annual-cancer-facts-and-figures/2016/cancer-facts-and-figures-2016.pdf.
Battersby, N. J., Juul, T., Christensen, P., Janjua, A. Z., Branagan, G., Emmertsen, K. J., et al. (2016). Predicting the risk of bowel-related quality-of-life impairment after restorative resection for rectal cancer: A multicenter cross-sectional study. Diseases of the Colon & Rectum,59(4), 270–280. CrossRef
Denlinger, C. S., & Engstrom, P. F. (2011). Colorectal cancer survivorship: Movement matters. Cancer Prev Res.,4(4), 502–511. CrossRef
Lemanne, D., Cassileth, B., & Gubili, J. (2013). The role of physical activity in cancer prevention, treatment, recovery, and survivorship. Oncology,27(6), 580–585. PubMed
Phillips, S. M., Alfano, C. M., Perna, F. M., & Glasgow, R. E. (2014). Accelerating translation of physical activity and cancer survivorship research into practice: Recommendations for a more integrated and collaborative approach. Cancer Epidemiology, Biomarkers & Prevention,23(5), 687–699. CrossRef
Siegel, R. L., Jemal, A., & Ward, E. M. (2009). Increase in incidence of colorectal cancer among young men and women in the United States. Cancer Epidemiology, Biomarkers & Prevention,18(6), 1695–1698. CrossRef
Herrinton, L. J., Altschuler, A., McMullen, C. K., Bulkley, J. E., Hornbrook, M. C., Sun, V., et al. (2016). Conversations for providers caring for rectal cancer patients: Comparison of long-term patient-centered outcomes for low rectal cancer patients facing ostomy or sphincter-sparing surgery. CA: A Cancer Journal for Clinicians,66(5), 387–397.
Beijers, A. J., Mols, F., Tjan-Heijnen, V. C., Faber, C. G., van de Poll-Franse, L. V., & Vreugdenhil, G. (2015). Peripheral neuropathy in colorectal cancer survivors: The influence of oxaliplatin administration. Results from the population-based PROFILES registry. Acta Oncologica,54(4), 463–469. PubMedCrossRef
Mohler, M. J., Coons, S. J., Hornbrook, M. C., Herrinton, L. J., Wendel, C. S., Grant, M., et al. (2008). The health-related quality of life in long-term colorectal cancer survivors study: Objectives, methods and patient sample. Current Medical Research and Opinion,24(7), 2059–2070. PubMedPubMedCentralCrossRef
Kushi, L. H., Doyle, C., McCullough, M., Rock, C. L., Demark-Wahnefried, W., Bandera, E. V., et al. (2012). American cancer society guidelines on nutrition and physical activity for cancer prevention: Reducing the risk of cancer with healthy food choices and physical activity. CA: A Cancer Journal for Clinicians,62(1), 30–67.
Godin, G., & Shephard, R. J. (1985). A simple method to assess exercise behavior in the community. Canadian Journal of Applied Sport Science,10(4), 141–146.
Amireault, S., Godin, G., Lacombe, J., & Sabiston, C. M. (2016). The use of the Godin-Shephard Leisure-Tie physical activity questionnaire in oncology research: A systematic review. BMC Medical Research Methodology,15, 60. CrossRef
Doyle, C., Kushi, L. H., Byers, T., Courneya, K. S., Demark-Wahnefried, W., Grant, B., et al. (2006). Nutrition and physical activity during and after cancer treatment: An American Cancer Society guide for informed choices. CA: A Cancer Journal for Clinicians,56(6), 323–353.
Trinh, H., Plotnikoff, R. C., Rhodes, R. E., North, S., & Courneya, K. S. (2011). Associations between physical activity and quality of life in a population-based sample of kidney cancer survivors. Cancer Epidemiology, Biomarkers & Prevention,20(5), 859–868. CrossRef
Speed-Andrews, A. E., Rhodes, R. E., Blanchard, C. M., Culos-Reed, S. N., Friedenreich, C. M., Belanger, L. J., et al. (2012). Medical, demographic and social cognitive correlates of physical activity in a population-based sample of colorectal cancer survivors. European Journal of Cancer Care,21(2), 187–196. PubMedCrossRef
Physical Activity Guidelines for Americans. US Department of Health and Human Services; 2008. Updated March 11,2013; Cited August 26, 2013 from http://www.health.gov/paguidelines/guidelines/default.aspx.
StataCorp. (2015). nptrend. Stata 14 Base Reference Manual. College Station, TX: Stata Press.
Sloan, J., Symonds, T., Vargas-Chanes, D., & Fridley, B. (2003). Practical guidelines for assessing the clinical significance of health-related quality of life changes within clinical trials. Drug Information Journal,37(1), 23–31. CrossRef
Kosinski, M., Zhao, S., Dedhiya, Z., Osterhaus, J. T., & Ware, J. E. (2000). Determining the minimally important changes in generic and disease-specific health-related quality of life questionnaires in clinical trials of rheumatoid arthritis. Arthritis and Rheumatism,43(7), 1478–1487. PubMedCrossRef
Di Fabio, F., Koller, M., Nascimbeni, R., Talarico, C., & Salerni, B. (2008). Long-term outcome after colorectal cancer resection. Patients’ self-reported quality of life, sexual dysfunction and surgeons awareness of patients’ needs. Tumori,94(1), 30–35. PubMed
Ottenbacher, A., Yu, M., Moser, R. P., Phillips, S. M., Alfano, C., & Perna, F. M. (2015). Population estimates of meeting strength training and aerobic guidelines, by gender and cancer survivorship status: Findings from the Health Information National Trends Survey (HINTS). Journal of Physical Activity & Health,12(5), 675–679. CrossRef
Blaney, J. M., Lowe-Strong, A., Rankin-Watt, J., Campbell, A., & Gracey, J. H. (2013). Cancer survivors’ exercise barriers, facilitators and preferences in the context of fatigue, quality of life and physical activity participation: A questionnaire-survey. Psychooncology,22(1), 186–194. PubMedCrossRef
- Physical activity, bowel function, and quality of life among rectal cancer survivors
Robert S. Krouse
Christopher S. Wendel
David O. Garcia
Larissa K. F. Temple
Scott B. Going
Mark C. Hornbrook
Joanna E. Bulkley
Carmit K. McMullen
Lisa J. Herrinton
- Springer International Publishing