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15-09-2022 | ORIGINAL PAPER

Mindfulness-Oriented Recovery Enhancement for Addictive Behavior, Psychiatric Distress, and Chronic Pain: A Multilevel Meta-Analysis of Randomized Controlled Trials

Auteurs: Anna Parisi, R. Lynae Roberts, Adam W. Hanley, Eric L. Garland

Gepubliceerd in: Mindfulness | Uitgave 10/2022

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Abstract

Objectives

Mindfulness-Oriented Recovery Enhancement (MORE) is an integrative intervention designed to ameliorate addiction, chronic pain, and psychiatric symptoms. Although multiple randomized controlled trials (RCTs) have examined the clinical efficacy of MORE, no study has quantitatively synthesized this body of research. Thus, we conducted a meta-analysis of RCTs examining the effects of MORE on addictive behaviors, craving, opioid dose, pain, and psychiatric symptoms.

Methods

Relevant manuscripts were identified through comprehensive searches of four bibliographic databases. Two- and three-level random-effects models were used to generate synthesized effect size estimates, and meta-regressions were performed to examine whether study and sample characteristics influenced the magnitude of aggregate effect sizes.

Results

Our search identified 16 manuscripts reporting data from eight RCTs (N = 816). Moderate to small effects in favor of MORE were observed for addictive behaviors (SMC =  − .54, p = .007), craving (SMC =  − .42, p = .010), opioid dose (MC =  − 17.95, p < .001), chronic pain (SMC =  − .60, p < .001), and psychiatric symptoms (SMC =  − .34, p < .001). MORE’s effects on psychiatric symptoms and craving were not moderated by participant race, gender, age, or income.

Conclusions

Study findings provide empirical evidence of MORE’s efficacy for a wide diversity of individuals, and as such, MORE should now be disseminated broadly throughout the healthcare system.

Meta-analysis Pre-registration: PROSPERO #CRD42022319006

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Metagegevens
Titel
Mindfulness-Oriented Recovery Enhancement for Addictive Behavior, Psychiatric Distress, and Chronic Pain: A Multilevel Meta-Analysis of Randomized Controlled Trials
Auteurs
Anna Parisi
R. Lynae Roberts
Adam W. Hanley
Eric L. Garland
Publicatiedatum
15-09-2022
Uitgeverij
Springer US
Gepubliceerd in
Mindfulness / Uitgave 10/2022
Print ISSN: 1868-8527
Elektronisch ISSN: 1868-8535
DOI
https://doi.org/10.1007/s12671-022-01964-x