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01-05-2008 | Response

Male Brains, Androgen, and the Cognitive Profile in Autism: Convergent Evidence from 2D:4D and Congenital Adrenal Hyperplasia

Auteurs: Christine M. Falter, Kate C. Plaisted, Greg Davis

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 5/2008

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Excerpt

The Extreme Male Brain (‘EMB’) theory of autism and the related proposal concerning elevated prenatal androgen (‘EPA’), account elegantly for some core features of autism, in particular those relating to social cognition. However, our recent findings suggest that other aspects of cognitive performance in autism are neither best characterized as an extreme form of the male profile, nor are determined by prenatal androgens. These results challenge EMB theory, and, together with convergent evidence from studies of Congenital Adrenal Hyperplasia (‘CAH’), also provide an effective challenge to the proposal that autism is triggered by elevated prenatal androgen. …
Literatuur
go back to reference Falter, C.M., Arroyo, M., & Davis, G.J. (2006). Testosterone: Activation or organization of spatial cognition? Biological Psychology, 73, 132–140.PubMedCrossRef Falter, C.M., Arroyo, M., & Davis, G.J. (2006). Testosterone: Activation or organization of spatial cognition? Biological Psychology, 73, 132–140.PubMedCrossRef
go back to reference Falter, C.M., Plaisted, K., & Davis, G. (2007). Visuo-spatial processing in autism—testing the predictions of extreme male brain theory. Journal of Autism and Developmental Disorders [Epub ahed of print]. Falter, C.M., Plaisted, K., & Davis, G. (2007). Visuo-spatial processing in autism—testing the predictions of extreme male brain theory. Journal of Autism and Developmental Disorders [Epub ahed of print].
go back to reference Hines, M., Fane, B.A., Pasterski, V.L., Mathews, G.A., Conway, G.S., & Brook, C. (2003). Spatial abilities following prenatal androgen abnormalities: Targeting and mental rotation performance in individuals with congenital adrenal hyperplasia. Psychoneuroendocrinology, 28, 1010–1026.PubMedCrossRef Hines, M., Fane, B.A., Pasterski, V.L., Mathews, G.A., Conway, G.S., & Brook, C. (2003). Spatial abilities following prenatal androgen abnormalities: Targeting and mental rotation performance in individuals with congenital adrenal hyperplasia. Psychoneuroendocrinology, 28, 1010–1026.PubMedCrossRef
go back to reference Resnick, S.M., Berenbaum, S.A., Gottesman, I.I., & Bouchard, T. (1986) Early hormonal influences on cognitive functioning in congenital adrenal hyperplasia. Developmental Psychology, 22, 191–198.CrossRef Resnick, S.M., Berenbaum, S.A., Gottesman, I.I., & Bouchard, T. (1986) Early hormonal influences on cognitive functioning in congenital adrenal hyperplasia. Developmental Psychology, 22, 191–198.CrossRef
Metagegevens
Titel
Male Brains, Androgen, and the Cognitive Profile in Autism: Convergent Evidence from 2D:4D and Congenital Adrenal Hyperplasia
Auteurs
Christine M. Falter
Kate C. Plaisted
Greg Davis
Publicatiedatum
01-05-2008
Uitgeverij
Springer US
Gepubliceerd in
Journal of Autism and Developmental Disorders / Uitgave 5/2008
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI
https://doi.org/10.1007/s10803-008-0552-z