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Gepubliceerd in: Quality of Life Research 9/2018

05-06-2018 | Brief Communication

The impact of axial spondyloarthritis on quality of life (QoL): a comparison with the impact of moderate to end-stage chronic kidney disease on QoL

Auteurs: Yu Heng Kwan, Warren Fong, Priscilla How, Hwee-Lin Wee, Ying Ying Leung, Jie Kie Phang, Nai Lee Lui, Chuen Seng Tan, Rahul Malhotra, Truls Østbye, Julian Thumboo

Gepubliceerd in: Quality of Life Research | Uitgave 9/2018

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Abstract

Purpose

The purpose of the study was to assess the impact of axial spondyloarthritis (axSpA) on patients’ quality of life (QoL) compared to patients with moderate to end-stage chronic kidney disease (CKD).

Methods

We conducted secondary analysis of QoL data obtained from patients with axSpA and CKD from 2011 to 2014. QoL was assessed using the SF-36 version 2 and KDQoL-SF for patients with axSpA and CKD, respectively. Patients with CKD were subcategorized to CKD-pre-dialysis, hemodialysis (CKD-HD) and peritoneal dialysis (CKD-PD). Linear regression was used to compare QoL between patients with axSpA and CKD after adjusting for age, gender, ethnicity, education level, and marital status.

Results

A total of 765 patients (mean age 54.6, 63.0% males, 69.0% Chinese) were analyzed, of which 188 (24.5%) had axSpA. Patients with axSpA had poorer SF-36 bodily pain (BP) scores (axSpA: reference; CKD-pre-dialysis β: 11.04, p < 0.001; CKD-HD β: 9.52, p < 0.001; CKD-PD β: 10.35, p < 0.001) and higher general health scores (axSpA: reference; CKD-pre-dialysis β: − 7.87, p < 0.001; CKD-HD β: − 7.14, p < 0.001, CKD-PD β: − 7.25, p < 0.001) as compared to patients with CKD. Generally, patients with axSpA had poorer SF-36 scores than patients with CKD-pre-dialysis and similar SF-36 scores compared to patients with CKD-HD or CKD-PD.

Conclusions

The burden of axSpA on QoL is not trivial and is comparable to patients with CKD-HD or CKD-PD.
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Metagegevens
Titel
The impact of axial spondyloarthritis on quality of life (QoL): a comparison with the impact of moderate to end-stage chronic kidney disease on QoL
Auteurs
Yu Heng Kwan
Warren Fong
Priscilla How
Hwee-Lin Wee
Ying Ying Leung
Jie Kie Phang
Nai Lee Lui
Chuen Seng Tan
Rahul Malhotra
Truls Østbye
Julian Thumboo
Publicatiedatum
05-06-2018
Uitgeverij
Springer International Publishing
Gepubliceerd in
Quality of Life Research / Uitgave 9/2018
Print ISSN: 0962-9343
Elektronisch ISSN: 1573-2649
DOI
https://doi.org/10.1007/s11136-018-1900-x

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