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20-06-2018 | Brief Communication | Uitgave 9/2018

Quality of Life Research 9/2018

Refining and supplementing candidate measures of psychological well-being for the NIH PROMIS®: qualitative results from a mixed cancer sample

Quality of Life Research > Uitgave 9/2018
John M. Salsman, Crystal L. Park, Elizabeth A. Hahn, Mallory A. Snyder, Login S. George, Michael F. Steger, Thomas Merluzzi, David Cella
Belangrijke opmerkingen
Portions of this manuscript were previously presented: Salsman, J.M., Park, C.L., Hahn, E.A., Snyder, M.A., George, L., Steger, M.F., & Cella, D. (2014, February). Refining and supplementing candidate measures of psychological well-being for the NIH PROMIS®: Results from a mixed cancer sample. Poster session presented at the American Psychosocial Oncology Society Annual Meeting. Tampa, FL.



The Patient-Reported Outcomes Measurement Information System (PROMIS) is a National Institutes of Health initiative designed to improve patient-reported outcomes using state-of-the-art psychometric methods. The aim of this study is to describe qualitative efforts to identify and refine items from psychological well-being subdomains for future testing, psychometric evaluation, and inclusion within PROMIS.


Seventy-two items from eight existing measures of positive affect, life satisfaction, meaning & purpose, and general self-efficacy were reviewed, and 48 new items were identified or written where content was lacking. Cognitive interviews were conducted in patients with cancer (n = 20; 5 interviews per item) to evaluate comprehensibility, clarity, and response options of candidate items.


A Lexile analysis confirmed that all items were written at the sixth grade reading level or below. A majority of patients demonstrated good understanding and logic for all items; however, nine items were identified as “moderately difficult” or “difficult” to answer. Patients reported a strong preference for confidence versus frequency response options for general self-efficacy items.


Altogether, 108 items were sufficiently comprehensible and clear (34 positive affect, 10 life satisfaction, 44 meaning & purpose, 20 general self-efficacy). Future research will examine the psychometric properties of the proposed item banks for further refinement and validation as PROMIS measures.

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